Ensuring The Utility And Sustainability Of Tissue Banks: Supporting Translational Research In Australia Through Informed Regulation And Community Engagement.
Funder
National Health and Medical Research Council
Funding Amount
$481,885.00
Summary
Tissue banks provide a critical resource for translational research into the causes and treatment of many diseases affecting children and adults, such as cancer.Their success and contribution to medical research depends on addressing the many unresolved and emerging challenges that impact their work. This is the first national empirical study engaging the Australian research community, legal experts tissue donors and the public about the challenges to tissue banks to inform ethico legal regulati ....Tissue banks provide a critical resource for translational research into the causes and treatment of many diseases affecting children and adults, such as cancer.Their success and contribution to medical research depends on addressing the many unresolved and emerging challenges that impact their work. This is the first national empirical study engaging the Australian research community, legal experts tissue donors and the public about the challenges to tissue banks to inform ethico legal regulation and deliver better health care systems.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170101514
Funder
Australian Research Council
Funding Amount
$372,000.00
Summary
The control of neuroplasticity in the brain. This project aims to determine how neuroplasticity – the brain’s ability to remodel and make new circuits – is controlled in both excitatory and inhibitory neurons. This capacity, vital for all cognitive functions, diminishes as people age. It is imperative to determine neuroplasticity’s mechanisms and how and why they change, but it is not known how both excitatory and inhibitory neurons contribute to neuroplasticity and how these dynamic alterations ....The control of neuroplasticity in the brain. This project aims to determine how neuroplasticity – the brain’s ability to remodel and make new circuits – is controlled in both excitatory and inhibitory neurons. This capacity, vital for all cognitive functions, diminishes as people age. It is imperative to determine neuroplasticity’s mechanisms and how and why they change, but it is not known how both excitatory and inhibitory neurons contribute to neuroplasticity and how these dynamic alterations are controlled. Understanding neuroplasticity is vital for learning, memory and healthy ageing throughout life.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE220100027
Funder
Australian Research Council
Funding Amount
$467,754.00
Summary
Making a life with less: youth underemployment over the life course. This project aims to investigate the experiences and impacts of underemployment on young people. Using high-quality longitudinal data and qualitative interviews, this project expects to generate new, foundational knowledge about the employment pathways young people take following underemployment and the strategies they use to mitigate its effects. In doing so, this project aims to reveal the impacts underemployment has on young ....Making a life with less: youth underemployment over the life course. This project aims to investigate the experiences and impacts of underemployment on young people. Using high-quality longitudinal data and qualitative interviews, this project expects to generate new, foundational knowledge about the employment pathways young people take following underemployment and the strategies they use to mitigate its effects. In doing so, this project aims to reveal the impacts underemployment has on young people’s lives within and outside work, including their relationships, family formation and well-being. This much-needed research aims to provide significant benefits for policymakers and service providers that improve the lives of young people.Read moreRead less
An empirically-derived conceptual framework for designing usable and useful wireless mobile applications. The technological challenges posed by mobile computing devices have taken priority over the issues of appropriate use and usability that will ultimately determine their success in real work environments.
This project investigates these issues, particularly the role played by the context of use in the usability and usefulness of mobile applications.
The project's aims will be realised ....An empirically-derived conceptual framework for designing usable and useful wireless mobile applications. The technological challenges posed by mobile computing devices have taken priority over the issues of appropriate use and usability that will ultimately determine their success in real work environments.
This project investigates these issues, particularly the role played by the context of use in the usability and usefulness of mobile applications.
The project's aims will be realised through ethnographic studies of mobile work practice, representative use scenarios and the development of an empirically grounded conceptual framework that can guide the design of usable mobile applications.
The results will increase the successful utilisation of mobile technology by Australian industries.
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A Biologically Responsive and Anatomically Authentic Human Nasal Model. As respiratory conditions caused by pollutants and viruses become more prevalent, human nasal models to study infection/protection mechanisms and nasal drug/vaccine delivery are increasingly important. This project aims to develop a world-first human nasal model to mimic both anatomical and biological aspects of the nasal cavity and predict the distribution and deposition of fine particles and the resultant biological respon ....A Biologically Responsive and Anatomically Authentic Human Nasal Model. As respiratory conditions caused by pollutants and viruses become more prevalent, human nasal models to study infection/protection mechanisms and nasal drug/vaccine delivery are increasingly important. This project aims to develop a world-first human nasal model to mimic both anatomical and biological aspects of the nasal cavity and predict the distribution and deposition of fine particles and the resultant biological response from the nasal mucosa. The aim is to overcome a key fabrication challenge - to 3D print an anatomically accurate nasal construct with a porous wall on which to grow and mature functional nasal tissue that lines a nasal cavity wall. The benefit would be enabling faster development of more targeted drugs and vaccines.Read moreRead less
Managing at the Margins: Women Making it Work in Precarious Times. This project aims to investigate the economic, social and emotional impacts of precarious work on women. Focusing on the challenges that arise from juggling precarious work with care responsibilities and/or demands from the social support system, the project identifies the strategies women have to manage these demands, and the impacts these demands have on everyday lives across different life stages. By combining otherwise separa ....Managing at the Margins: Women Making it Work in Precarious Times. This project aims to investigate the economic, social and emotional impacts of precarious work on women. Focusing on the challenges that arise from juggling precarious work with care responsibilities and/or demands from the social support system, the project identifies the strategies women have to manage these demands, and the impacts these demands have on everyday lives across different life stages. By combining otherwise separate bodies of literature with innovative quantitative and qualitative data, the project seeks to generate new knowledge about the impacts of precarious work on women and families. This knowledge is expected to inform policies and services to improve women’s lives and promote economic inclusion and social cohesion.Read moreRead less
Special Research Initiatives - Grant ID: SR200200441
Funder
Australian Research Council
Funding Amount
$289,479.00
Summary
Enabling cultures of bushfire readiness in Australian communities. This project aims to improve bushfire preparation by examining how cultural connections to landscape, place and community affect the ways in which people respond to information about bushfire hazards. Australia’s Black Summer showed that many households are inadequately prepared for the ‘new normal’ of faster, fiercer fires. This is particularly concerning on the urban fringe, where rapid development is changing landscapes, and h ....Enabling cultures of bushfire readiness in Australian communities. This project aims to improve bushfire preparation by examining how cultural connections to landscape, place and community affect the ways in which people respond to information about bushfire hazards. Australia’s Black Summer showed that many households are inadequately prepared for the ‘new normal’ of faster, fiercer fires. This is particularly concerning on the urban fringe, where rapid development is changing landscapes, and households face complex socio-economic challenges. The study aims to contribute to the safety of Australians by enabling emergency services to more effectively engage diverse communities in dialogue that promotes bushfire readiness, by connecting with place-based values, aspirations and behaviours.Read moreRead less
Will older workers change their retirement plans in line with the Government’s calls for later retirement? The study will inform and contribute to the integration of retirement policy reform across all tiers of Government. It will especially project probabilities of change in workforce and retirement behaviour, and evaluate the likely efficacy of policy measures aimed at encouraging labour market participation among older workers and reversing current trends to early retirement. The study is tim ....Will older workers change their retirement plans in line with the Government’s calls for later retirement? The study will inform and contribute to the integration of retirement policy reform across all tiers of Government. It will especially project probabilities of change in workforce and retirement behaviour, and evaluate the likely efficacy of policy measures aimed at encouraging labour market participation among older workers and reversing current trends to early retirement. The study is timely because population ageing in Australia is just becoming a factor in labour market considerations, but its effects (which differ markedly by region) will soon escalate. Read moreRead less
Special Research Initiatives - Grant ID: SR1101002
Funder
Australian Research Council
Funding Amount
$21,000,000.00
Summary
Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and ....Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and the ability to control and influence this process. Stem Cells Australia will deliver new methods for stem cell propagation and manipulation, new translational technologies for therapeutic applications, and will prepare Australia’s future stem cell scientific leaders.Read moreRead less
Multi-Country Study on Health Effects of Bushfire Air Pollution. Catastrophic bushfires are a major natural disaster, causing serious air pollution. However, aligning bushfire air pollution and public health policies becomes a significant challenge, because limited studies are available on relationships between bushfire air pollution and human health, particularly for the prolonged exposure. We will characterize the nature of the relationships between bushfire air pollution and mortality/morbidi ....Multi-Country Study on Health Effects of Bushfire Air Pollution. Catastrophic bushfires are a major natural disaster, causing serious air pollution. However, aligning bushfire air pollution and public health policies becomes a significant challenge, because limited studies are available on relationships between bushfire air pollution and human health, particularly for the prolonged exposure. We will characterize the nature of the relationships between bushfire air pollution and mortality/morbidity by developing a multi-country study; and estimate the burden of diseases attributed to bushfire air pollution. This project will provide essential scientific evidence to policy-makers and stakeholders in the development, prioritization and implementation of health protection strategies and policies.
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