Creating a non-invasive window into the mind. This project aims to create better tools to study the human mind. This project expects to generate new knowledge that can be used to non-invasively image neuronal activity. Expected outcomes include the development of unique new Magnetic Resonance Imaging (MRI) instruments to study neuronal activity in both highly controlled laboratory conditions and in humans, with the spatial and temporal resolution needed to study the neuronal circuitry that drive ....Creating a non-invasive window into the mind. This project aims to create better tools to study the human mind. This project expects to generate new knowledge that can be used to non-invasively image neuronal activity. Expected outcomes include the development of unique new Magnetic Resonance Imaging (MRI) instruments to study neuronal activity in both highly controlled laboratory conditions and in humans, with the spatial and temporal resolution needed to study the neuronal circuitry that drives low and high-level brain functions, i.e., creating a window into the mind. In the future, outcomes from this study could improve our understanding of mental disorders, advance computer brain interface technology, and inspire the next paradigm shift in artificial intelligence.Read moreRead less
A Biologically Responsive and Anatomically Authentic Human Nasal Model. As respiratory conditions caused by pollutants and viruses become more prevalent, human nasal models to study infection/protection mechanisms and nasal drug/vaccine delivery are increasingly important. This project aims to develop a world-first human nasal model to mimic both anatomical and biological aspects of the nasal cavity and predict the distribution and deposition of fine particles and the resultant biological respon ....A Biologically Responsive and Anatomically Authentic Human Nasal Model. As respiratory conditions caused by pollutants and viruses become more prevalent, human nasal models to study infection/protection mechanisms and nasal drug/vaccine delivery are increasingly important. This project aims to develop a world-first human nasal model to mimic both anatomical and biological aspects of the nasal cavity and predict the distribution and deposition of fine particles and the resultant biological response from the nasal mucosa. The aim is to overcome a key fabrication challenge - to 3D print an anatomically accurate nasal construct with a porous wall on which to grow and mature functional nasal tissue that lines a nasal cavity wall. The benefit would be enabling faster development of more targeted drugs and vaccines.Read moreRead less
A Micro-Physiological System to Mimic Human Microbiome-Organ Interactions. This project aims to mimic gut microbiome-organ interactions by developing a microbial-gut coculture chip, which can reversibly interface with other organs-on-chips. This is achieved through the systematic integration of highly customisable biofabrication and microfluidic technologies. This project fills a critical technological gap in the availability of an animal-alternative system to investigate microbiome-host interac ....A Micro-Physiological System to Mimic Human Microbiome-Organ Interactions. This project aims to mimic gut microbiome-organ interactions by developing a microbial-gut coculture chip, which can reversibly interface with other organs-on-chips. This is achieved through the systematic integration of highly customisable biofabrication and microfluidic technologies. This project fills a critical technological gap in the availability of an animal-alternative system to investigate microbiome-host interactions, which will greatly complement existing meta-omics approaches. The deliverables include a proof-of-concept system validated for gut-liver axis as well as the creation of new knowledge and framework to assimilate design thinking and advanced manufacturing to elevate tissue engineering into physiology engineering. Read moreRead less
Dopant engineering of diamond for quantum sensing technologies. Doped diamonds are central to a growing range of quantum-sensing technologies for future industries, including medical and defence. These diamonds must be doped with both an electron donors and active 'quantum-defects' to operate. Within existing devices, the electronic donors also create parasitic magnetic noise, due to their magnetic-spin properties. In this project we aim to investigate the growth of diamond with new electronic d ....Dopant engineering of diamond for quantum sensing technologies. Doped diamonds are central to a growing range of quantum-sensing technologies for future industries, including medical and defence. These diamonds must be doped with both an electron donors and active 'quantum-defects' to operate. Within existing devices, the electronic donors also create parasitic magnetic noise, due to their magnetic-spin properties. In this project we aim to investigate the growth of diamond with new electronic donors, aiming for spin-free and thus noise-free dopant properties. This should provide significant benefits to defence capability, through enhanced magnetic anomaly detection in naval environments, and health outcomes, through neural sensing of brain signals at room temperature.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE120101721
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Probing the excited states of organic semiconductor systems with photoinduced absorption spectroscopy. Plastic semiconductors have the potential to revolutionise consumer electronics by enabling cheap, flexible and low power devices. The success of these devices depends on our understanding of the optical and electronic properties of the materials, which this project aims to address through the use of photoinduced absorption spectroscopy.
Synthesis of enriched silicon for long-lived donor quantum states. We have discovered a method to make silicon highly enriched in the desirable spin-zero isotope using readily available ion implantation tools. This “semiconductor vacuum” is essential for building future quantum computer devices using the quantum spin of millions of implanted atoms with revolutionary capabilities. We have demonstrated long-lived implanted donor atom quantum states in prototype material, made possible by the deple ....Synthesis of enriched silicon for long-lived donor quantum states. We have discovered a method to make silicon highly enriched in the desirable spin-zero isotope using readily available ion implantation tools. This “semiconductor vacuum” is essential for building future quantum computer devices using the quantum spin of millions of implanted atoms with revolutionary capabilities. We have demonstrated long-lived implanted donor atom quantum states in prototype material, made possible by the depletion of background spins in natural silicon and now aim to push the enrichment to greater extremes. We will integrate the extreme material into functional devices that use electrically detected electron spin resonance to probe exceptionally durable quantum states and open a near-term pathway to large-scale devices.Read moreRead less
A new in-situ structural measurement capability during nanoindentation. A new in-situ structural measurement capability during nanoindentation. This project aims to develop an in-situ Raman capability to obtain dynamic structural and mechanical behaviour of materials as a function of pressure during nanoindentation; and apply the new capability to directly monitor phase changes in silicon and germanium under pressure and correlate them with the simultaneous electrical responses. Anticipated outc ....A new in-situ structural measurement capability during nanoindentation. A new in-situ structural measurement capability during nanoindentation. This project aims to develop an in-situ Raman capability to obtain dynamic structural and mechanical behaviour of materials as a function of pressure during nanoindentation; and apply the new capability to directly monitor phase changes in silicon and germanium under pressure and correlate them with the simultaneous electrical responses. Anticipated outcomes are new instrumentation to directly probe the pressure-temperature phase diagram, and measure electrical properties of novel end phases in these semiconductors.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170101170
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
Electronic structure on both sides of the Fermi level in molecular material. This project aims to develop an inverse photoemission spectrometer to elucidate the electronic properties of molecular materials. In tandem with traditional photoemission, the spectrometer will measure the electronic structure of small molecules for organic electronics and two-dimensional graphene-analogous polymers, providing information critical to their development and use. The instrument is expected to bring critica ....Electronic structure on both sides of the Fermi level in molecular material. This project aims to develop an inverse photoemission spectrometer to elucidate the electronic properties of molecular materials. In tandem with traditional photoemission, the spectrometer will measure the electronic structure of small molecules for organic electronics and two-dimensional graphene-analogous polymers, providing information critical to their development and use. The instrument is expected to bring critical insight to the burgeoning field of molecular materials, with potential widespread applications from energy conversion to sensing and electronics, with benefits across sectors.Read moreRead less
Development and investigation of functional solid-state nano-pore membranes. This project aims to develop robust membranes with molecular size pores using atomically thin layers and silicon-based materials. Using state-of-the-art characterisation techniques and computer simulations it seeks to derive a fundamental understanding of the membrane formation processes and pore properties. Expected outcomes include industrially compatible fabrication processes that should enable rapid integration of t ....Development and investigation of functional solid-state nano-pore membranes. This project aims to develop robust membranes with molecular size pores using atomically thin layers and silicon-based materials. Using state-of-the-art characterisation techniques and computer simulations it seeks to derive a fundamental understanding of the membrane formation processes and pore properties. Expected outcomes include industrially compatible fabrication processes that should enable rapid integration of the membranes into advanced device applications as well as enhancing national capabilities for materials characterisation. Significant benefits should result from novel applications of the technologies in the areas of medical- and bio-sensing, filtration, and lab-on-the-chip devices.Read moreRead less
Enlightening single rare-earth atoms in scanning-tunnelling microscopy. This project aims to create a tool to systematically engineer optical properties of emitters in solids by understanding and manipulating materials atom by atom. The tool – an optically enhanced scanning tunnelling microscope – is expected to drive future developments in optical technologies. The project expects to deliver an atomic-scale understanding of rare-earth sites optimised for sensing and coherence. The expected outc ....Enlightening single rare-earth atoms in scanning-tunnelling microscopy. This project aims to create a tool to systematically engineer optical properties of emitters in solids by understanding and manipulating materials atom by atom. The tool – an optically enhanced scanning tunnelling microscope – is expected to drive future developments in optical technologies. The project expects to deliver an atomic-scale understanding of rare-earth sites optimised for sensing and coherence. The expected outcomes include highly developed theoretical insights into solid-state emitters and how to control their interactions with light and other fields. The expected benefit based on the ability to engineer optimised emitters for optical sensors and quantum technologies will transform material science from exploration to design.Read moreRead less