Creating a non-invasive window into the mind. This project aims to create better tools to study the human mind. This project expects to generate new knowledge that can be used to non-invasively image neuronal activity. Expected outcomes include the development of unique new Magnetic Resonance Imaging (MRI) instruments to study neuronal activity in both highly controlled laboratory conditions and in humans, with the spatial and temporal resolution needed to study the neuronal circuitry that drive ....Creating a non-invasive window into the mind. This project aims to create better tools to study the human mind. This project expects to generate new knowledge that can be used to non-invasively image neuronal activity. Expected outcomes include the development of unique new Magnetic Resonance Imaging (MRI) instruments to study neuronal activity in both highly controlled laboratory conditions and in humans, with the spatial and temporal resolution needed to study the neuronal circuitry that drives low and high-level brain functions, i.e., creating a window into the mind. In the future, outcomes from this study could improve our understanding of mental disorders, advance computer brain interface technology, and inspire the next paradigm shift in artificial intelligence.Read moreRead less
A Biologically Responsive and Anatomically Authentic Human Nasal Model. As respiratory conditions caused by pollutants and viruses become more prevalent, human nasal models to study infection/protection mechanisms and nasal drug/vaccine delivery are increasingly important. This project aims to develop a world-first human nasal model to mimic both anatomical and biological aspects of the nasal cavity and predict the distribution and deposition of fine particles and the resultant biological respon ....A Biologically Responsive and Anatomically Authentic Human Nasal Model. As respiratory conditions caused by pollutants and viruses become more prevalent, human nasal models to study infection/protection mechanisms and nasal drug/vaccine delivery are increasingly important. This project aims to develop a world-first human nasal model to mimic both anatomical and biological aspects of the nasal cavity and predict the distribution and deposition of fine particles and the resultant biological response from the nasal mucosa. The aim is to overcome a key fabrication challenge - to 3D print an anatomically accurate nasal construct with a porous wall on which to grow and mature functional nasal tissue that lines a nasal cavity wall. The benefit would be enabling faster development of more targeted drugs and vaccines.Read moreRead less
A Micro-Physiological System to Mimic Human Microbiome-Organ Interactions. This project aims to mimic gut microbiome-organ interactions by developing a microbial-gut coculture chip, which can reversibly interface with other organs-on-chips. This is achieved through the systematic integration of highly customisable biofabrication and microfluidic technologies. This project fills a critical technological gap in the availability of an animal-alternative system to investigate microbiome-host interac ....A Micro-Physiological System to Mimic Human Microbiome-Organ Interactions. This project aims to mimic gut microbiome-organ interactions by developing a microbial-gut coculture chip, which can reversibly interface with other organs-on-chips. This is achieved through the systematic integration of highly customisable biofabrication and microfluidic technologies. This project fills a critical technological gap in the availability of an animal-alternative system to investigate microbiome-host interactions, which will greatly complement existing meta-omics approaches. The deliverables include a proof-of-concept system validated for gut-liver axis as well as the creation of new knowledge and framework to assimilate design thinking and advanced manufacturing to elevate tissue engineering into physiology engineering. Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE120101721
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Probing the excited states of organic semiconductor systems with photoinduced absorption spectroscopy. Plastic semiconductors have the potential to revolutionise consumer electronics by enabling cheap, flexible and low power devices. The success of these devices depends on our understanding of the optical and electronic properties of the materials, which this project aims to address through the use of photoinduced absorption spectroscopy.
Discovery Early Career Researcher Award - Grant ID: DE170101170
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
Electronic structure on both sides of the Fermi level in molecular material. This project aims to develop an inverse photoemission spectrometer to elucidate the electronic properties of molecular materials. In tandem with traditional photoemission, the spectrometer will measure the electronic structure of small molecules for organic electronics and two-dimensional graphene-analogous polymers, providing information critical to their development and use. The instrument is expected to bring critica ....Electronic structure on both sides of the Fermi level in molecular material. This project aims to develop an inverse photoemission spectrometer to elucidate the electronic properties of molecular materials. In tandem with traditional photoemission, the spectrometer will measure the electronic structure of small molecules for organic electronics and two-dimensional graphene-analogous polymers, providing information critical to their development and use. The instrument is expected to bring critical insight to the burgeoning field of molecular materials, with potential widespread applications from energy conversion to sensing and electronics, with benefits across sectors.Read moreRead less
Surface modification of semiconducting organic charge transfer complexes with metal nanoparticles to create a new class of multifunctional materials. This project aims to deliver a facile and cheap method to produce a class of nanostructured composite materials to be used in applications which will have environmental and social benefits such as photocatalyst development for water purification, biosensing and the creation of antibacterial fabrics to prevent the spread of infection.
ARC Centre of Excellence for Nanoscale BioPhotonics. The CNBP brings together physicists, chemists and biologists focused on a grand challenge controlling nanoscale interactions between light and matter to probe the complex and dynamic nanoenvironments within living organisms. The emerging convergence of nanoscience and photonics offers the opportunity of using light to interrogate nanoscale domains, providing unprecedentedly localised measurements. This will allow biological scientists to unde ....ARC Centre of Excellence for Nanoscale BioPhotonics. The CNBP brings together physicists, chemists and biologists focused on a grand challenge controlling nanoscale interactions between light and matter to probe the complex and dynamic nanoenvironments within living organisms. The emerging convergence of nanoscience and photonics offers the opportunity of using light to interrogate nanoscale domains, providing unprecedentedly localised measurements. This will allow biological scientists to understand how single cells react to and communicate with their surroundings. This science will underpin a new generation of devices capable of probing the response of cells within individuals to environmental conditions or treatment, creating innovative and powerful new sensing platforms.Read moreRead less