We have discovered a single tumour factor which causes cancer cachexia, a wasting condition that is one of the worst complications of malignancy, for which there is no current effective treatment. We have developed antibodies which effectively block this condition in preclinical models and have produced human/humanised version of this. This application is to characterise these human antibodies to allow us proceed to clinical trials.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0347797
Funder
Australian Research Council
Funding Amount
$263,000.00
Summary
A Versatile High-resolution X-ray Diffractometer for Materials Research. The aim of this project is to establish a state-of-the-art triple-axis x-ray diffraction facility capable of non-destructively analysing complex semiconductor materials and structures investigated by all Australian semiconductor-growing groups. Growers and device engineers will be able to control growth processes accurately and correlate device performance with structural analysis. Modern triple-axis instruments can also b ....A Versatile High-resolution X-ray Diffractometer for Materials Research. The aim of this project is to establish a state-of-the-art triple-axis x-ray diffraction facility capable of non-destructively analysing complex semiconductor materials and structures investigated by all Australian semiconductor-growing groups. Growers and device engineers will be able to control growth processes accurately and correlate device performance with structural analysis. Modern triple-axis instruments can also be used for high-resolution texture analysis and surface reflectivity measurements on numerous types of materials. Thus chemists, geologists, and materials scientists with interests outside of the semiconductor growth community will gain substantial benefit from this instrument for the investigation of materials of technological and economic importance.Read moreRead less
Applying advanced synchrotron radiation-based techniques to determine the connection between the geometric and electronic structure of semiconductor nanocrystals. As the dimensions of nanocrystals become small unique optical and electronic properties are observed, forming the basis of many new technologies. The properties of interest depend on the fine-scale, local details of the nanocrystal structure, which may differ considerably from bulk-like. Advanced synchrotron radiation techniques wil ....Applying advanced synchrotron radiation-based techniques to determine the connection between the geometric and electronic structure of semiconductor nanocrystals. As the dimensions of nanocrystals become small unique optical and electronic properties are observed, forming the basis of many new technologies. The properties of interest depend on the fine-scale, local details of the nanocrystal structure, which may differ considerably from bulk-like. Advanced synchrotron radiation techniques will be used to investigate the relationship between the local geometric and electronic structure of semiconductor nanocrystals. Insight will be provided to their formation and stability, and the important mechanisms of their unique optical and electronic properties will be identified. Such fundamental information is necessary to facilitate innovative application of future nanocrystal technology.Read moreRead less
ARC Centre of Excellence in Exciton Science. This Centre aims to manipulate the way light energy is absorbed, transported and transformed in advanced molecular materials. The research programme spans high-throughput computational screening, single molecule photochemistry and ultrafast spectroscopy and embraces innovative outreach and commercial translation activities. The Centre plans to capture the knowledge generated as new intellectual property, materials processing know-how, and through the ....ARC Centre of Excellence in Exciton Science. This Centre aims to manipulate the way light energy is absorbed, transported and transformed in advanced molecular materials. The research programme spans high-throughput computational screening, single molecule photochemistry and ultrafast spectroscopy and embraces innovative outreach and commercial translation activities. The Centre plans to capture the knowledge generated as new intellectual property, materials processing know-how, and through the creation of new employment opportunities. The expected outcomes and benefits include new Australian technologies in solar energy conversion, energy-efficient lighting and displays, security labelling and optical sensor platforms for defence.Read moreRead less
Non-equilibrium material phases. This project aims to synthesise and characterise exotic materials produced in the laboratory under conditions that replicate those inside planets and stars. Highly non-equilibrium processing methods are needed to find entirely new material forms of elements and compounds created under extreme pressure and temperature. The project will use its laser-based synthesis method to explore and understand the non-equilibrium pathways and develop new materials. Understandi ....Non-equilibrium material phases. This project aims to synthesise and characterise exotic materials produced in the laboratory under conditions that replicate those inside planets and stars. Highly non-equilibrium processing methods are needed to find entirely new material forms of elements and compounds created under extreme pressure and temperature. The project will use its laser-based synthesis method to explore and understand the non-equilibrium pathways and develop new materials. Understanding how these materials form could lead to the next materials revolution. This research will lead to materials that industry sectors can exploit for commercial benefits.Read moreRead less
Boron nitride nanotubes for tunable conductivity. The proposed research in nanotubes falls into the national research priority areas of advanced materials and breakthrough science. This ANU research group has a leading role in Boron Nitride (BN) nanotube research internationally. The proposed collaborative research will enhance this position and further improve the nation's research profile in nanotechnology. New intellectual properties will be generated if the project is successful, which wi ....Boron nitride nanotubes for tunable conductivity. The proposed research in nanotubes falls into the national research priority areas of advanced materials and breakthrough science. This ANU research group has a leading role in Boron Nitride (BN) nanotube research internationally. The proposed collaborative research will enhance this position and further improve the nation's research profile in nanotechnology. New intellectual properties will be generated if the project is successful, which will benefit the commercialization activity of BN nanotubes at ANU. New PhD and undergraduate students will be trained by the proposed cutting edge research project.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0454166
Funder
Australian Research Council
Funding Amount
$1,305,029.00
Summary
Nanoscale Materials Characterization Facility. We request a transmission and a scanning electron microscope, each with specialist electron probes smaller than a nanometre, which can selectively analyse the atomic structure and chemistry of sub-nanometre regions of material.
These capabilities are essential to advance a large range of research projects at the cutting-edge of materials science and engineering, undertaken by Victoria's leading research institutions: five Victorian universities, ....Nanoscale Materials Characterization Facility. We request a transmission and a scanning electron microscope, each with specialist electron probes smaller than a nanometre, which can selectively analyse the atomic structure and chemistry of sub-nanometre regions of material.
These capabilities are essential to advance a large range of research projects at the cutting-edge of materials science and engineering, undertaken by Victoria's leading research institutions: five Victorian universities, the CSIRO, Nanotechnology Victoria Ltd, the Victorian Centre for Advanced Materials Manufacturing and the CRC for Microtechnology. Together they have contributed $2.58 million to this project.
This state-of-the-art facility will include the highest spatial resolution microscope in Australia.
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