A Biologically Responsive and Anatomically Authentic Human Nasal Model. As respiratory conditions caused by pollutants and viruses become more prevalent, human nasal models to study infection/protection mechanisms and nasal drug/vaccine delivery are increasingly important. This project aims to develop a world-first human nasal model to mimic both anatomical and biological aspects of the nasal cavity and predict the distribution and deposition of fine particles and the resultant biological respon ....A Biologically Responsive and Anatomically Authentic Human Nasal Model. As respiratory conditions caused by pollutants and viruses become more prevalent, human nasal models to study infection/protection mechanisms and nasal drug/vaccine delivery are increasingly important. This project aims to develop a world-first human nasal model to mimic both anatomical and biological aspects of the nasal cavity and predict the distribution and deposition of fine particles and the resultant biological response from the nasal mucosa. The aim is to overcome a key fabrication challenge - to 3D print an anatomically accurate nasal construct with a porous wall on which to grow and mature functional nasal tissue that lines a nasal cavity wall. The benefit would be enabling faster development of more targeted drugs and vaccines.Read moreRead less
Towards an Active and Passive L- and P-band soil moisture satellite mission. This project tests alternate configurations for remote sensing of soil moisture using a new state-of-the-art Active/Passive (ie radar/radiometer) P-/L-band (ie microwave) satellite concept through a series of airborne field experiments. Timely soil moisture information is critical to improved water management for food production in the face of climate variability. The challenge is to do this accurately over large areas ....Towards an Active and Passive L- and P-band soil moisture satellite mission. This project tests alternate configurations for remote sensing of soil moisture using a new state-of-the-art Active/Passive (ie radar/radiometer) P-/L-band (ie microwave) satellite concept through a series of airborne field experiments. Timely soil moisture information is critical to improved water management for food production in the face of climate variability. The challenge is to do this accurately over large areas with an appropriate spatio-temporal detail, and for a soil depth that closely approximates the layer which impacts crop/pasture growth and influences management decisions. The longer P-band allows deeper penetration into the soil while the active/passive combination uses the respective resolution and accuracy characteristics.Read moreRead less
Microfluidic technology to help understand physical damage to brain cells. Understanding the organisation, structure and mechanisms of the human brain and nervous system remains one of the biggest challenges of science. This project aims to develop a new cell culture platform to form defined molecular networks of brain cells and to monitor changes throughout the network in response to a small localised injury within the network. This innovative platform will be used to help understand changes wi ....Microfluidic technology to help understand physical damage to brain cells. Understanding the organisation, structure and mechanisms of the human brain and nervous system remains one of the biggest challenges of science. This project aims to develop a new cell culture platform to form defined molecular networks of brain cells and to monitor changes throughout the network in response to a small localised injury within the network. This innovative platform will be used to help understand changes within cells in response to physical damage to networks of brain cells. This is one of the major causes of death and disability in developed nations, and is identified as a risk factor for a range of neurodegenerative diseases including Alzheimer's, Parkinson's and motor neuron disease.Read moreRead less