Generating multi-component scaffolding to influence the differentiation of embryonic stem cells. Nervous system diseases are debilitating and will develop in over 50 per cent of people at some time in their life. This project will develop strategies so that stem cells can be utilised to encourage brain repair for the treatment of Parkinson's disease. The technology developed will also be of benefit for the treatment of other nervous system disorders.
A new energy absorption system for brain injury mitigation. This research aims to propose and investigate a next generation high-energy absorbing helmet pad that will protect the Australian Defence Force soldiers against both ballistic and blast threats. New fundamental knowledge in the area of high-energy absorbing metamaterials will be obtained by using numerical modelling and experimental studies. The expected outcomes of the project include the development of a new wearable energy absorbing ....A new energy absorption system for brain injury mitigation. This research aims to propose and investigate a next generation high-energy absorbing helmet pad that will protect the Australian Defence Force soldiers against both ballistic and blast threats. New fundamental knowledge in the area of high-energy absorbing metamaterials will be obtained by using numerical modelling and experimental studies. The expected outcomes of the project include the development of a new wearable energy absorbing pad which can be used as the next generation combat helmet liners and accessories. The novel high-performance energy absorption system will have a wide range of direct applications in future personal armour, as well as sports gears and elderly healthcare products.Read moreRead less
Engineering functional nerves using microtailored culture systems. The aim of this work is to develop new culture systems for developing and growing nerves outside of the body. The project will generate knowledge and engineering technology for production of neural implants suitable for medical applications. The availability of engineered nerve grafts to repair neural injuries will improve patient health outcomes.
Global trends in oceanic wind speed and wave height. This project will determine whether winds and waves over the world's oceans have changed over the past 30 years. Such information is critically important in understanding global climate change, evaporation, air-sea interaction and to safely design and operate coastal and offshore facilities.
Using nanostructured biomaterials and stem cells to repair spinal cord injuries. There is currently no effective cure for spinal cord injuries and the consequences to the patient are devastating. Spinal cord injuries affects limb, bowel, bladder and sexual function, and many people with these injuries strugle to maintain their independence. Because people can live for many years after spinal cord damage, the financial and social costs are immense, as many are dependent on the help of others for ....Using nanostructured biomaterials and stem cells to repair spinal cord injuries. There is currently no effective cure for spinal cord injuries and the consequences to the patient are devastating. Spinal cord injuries affects limb, bowel, bladder and sexual function, and many people with these injuries strugle to maintain their independence. Because people can live for many years after spinal cord damage, the financial and social costs are immense, as many are dependent on the help of others for their survival. This proposal tackles this urgent problem by applying advanced nanostructured materials with stem cells, to assist the body in the repair of the spinal cord following injury. Read moreRead less
Predicting environmental extremes in a period of climate change. This project has the potential to reduce the uncertainty in the predictions of extreme winds and waves used to design and operate coastal and offshore facilities. Predictions are typically achieved by extrapolating recorded data to predict probable extremes. The uncertainties associated with this approach are very large. This project aims to develop a new approach called ‘large ensemble aggregate’ analysis, which brings together da ....Predicting environmental extremes in a period of climate change. This project has the potential to reduce the uncertainty in the predictions of extreme winds and waves used to design and operate coastal and offshore facilities. Predictions are typically achieved by extrapolating recorded data to predict probable extremes. The uncertainties associated with this approach are very large. This project aims to develop a new approach called ‘large ensemble aggregate’ analysis, which brings together data from alternative model predictions or alternative measurement locations to expand the effective data and avoid the necessity for statistical extrapolation. This approach may significantly reduce the uncertainty in estimating extreme values. This would reduce the cost of constructing coastal and offshore facilities and decrease the risk of catastrophic failure.Read moreRead less
Functionalisation of boron nitride nanotubes: preparation, underlying mechanism and potential sensor applications. Building on Australian expertise in synthesis and characterisations of nanomaterials, this project will carry out comprehensive and systematic research in functionalisation of boron nitride nanotubes and explore their potential applications. The success of this project will enhance Australian international reputation in nanotechnology development and ensure our leading position in t ....Functionalisation of boron nitride nanotubes: preparation, underlying mechanism and potential sensor applications. Building on Australian expertise in synthesis and characterisations of nanomaterials, this project will carry out comprehensive and systematic research in functionalisation of boron nitride nanotubes and explore their potential applications. The success of this project will enhance Australian international reputation in nanotechnology development and ensure our leading position in this highly competitive area. The outcome of this project will promote the potentially functional applications of boron nitride nanotubes in various nanodevices and nanosensors. It will also offer trainings for Australia's future scientists and will further strengthen international scientific collaboration in these fields.Read moreRead less
Towards autonomous structural safety prognostics: integrating in-situ imaging and predictive modelling. This project aims to advance a scientific basis for autonomous safety prognostics by developing predictive models and in-situ damage imaging principles. Development of this new health prognostic approach will overcome the significant challenge of safety assurance of composite structures in the presence of in-service damage, which is largely hidden.
Synthesis of novel phases from Group IV elements under extreme pressure. Materials based on the group IV elements carbon, silicon and germanium are technologically important for a wide range of current applications. When exposed to extreme pressure, these materials can form entirely new phases with novel and potentially useful properties. Since there have been few previous attempts to establish which of the new phases are stable on pressure release and to measure their properties for subsequent ....Synthesis of novel phases from Group IV elements under extreme pressure. Materials based on the group IV elements carbon, silicon and germanium are technologically important for a wide range of current applications. When exposed to extreme pressure, these materials can form entirely new phases with novel and potentially useful properties. Since there have been few previous attempts to establish which of the new phases are stable on pressure release and to measure their properties for subsequent exploitation, this project aims to use novel approaches to address these topics. The expected outcome of this project will be new phases of group IV elements with novel properties that have potential for commercial exploitation.Read moreRead less
Development of Control Methodologies for Drug Dosing in Biomedical Engineering. This research proposal is very relevant to the National Research Priorities in the areas of Frontier Technologies and Breakthrough science. At a broader level, we aim to assist in the development of a national competence in what has been an emerging and promising discipline. The research will develop fundamental and enabling laws and techniques for drug administration to regulate physiological variables such as blood ....Development of Control Methodologies for Drug Dosing in Biomedical Engineering. This research proposal is very relevant to the National Research Priorities in the areas of Frontier Technologies and Breakthrough science. At a broader level, we aim to assist in the development of a national competence in what has been an emerging and promising discipline. The research will develop fundamental and enabling laws and techniques for drug administration to regulate physiological variables such as blood pressure and degree of consciousness in critical care patients.Read moreRead less