Talent Mismatch: Evidence from Australian Administrative Tax Records. The project aims to study the skill composition of the Australian workforce. Changes in the macroeconomic and technology environments make it hard to predict skill shortage. The project expects to develop macroeconomic models quantifying skill-mismatch of university graduates, identify sources of mismatch, highlight gender and generational differences, and estimate associated costs to Australia. The expected outcomes are to he ....Talent Mismatch: Evidence from Australian Administrative Tax Records. The project aims to study the skill composition of the Australian workforce. Changes in the macroeconomic and technology environments make it hard to predict skill shortage. The project expects to develop macroeconomic models quantifying skill-mismatch of university graduates, identify sources of mismatch, highlight gender and generational differences, and estimate associated costs to Australia. The expected outcomes are to help shape policy recommendations on the funding of tertiary education in a changing economic climate. This should provide significant benefits to Australians, as policies shaping the tertiary education system affect individual income and the aggregate economy by determining labour supply and taxpayers' financial burden.Read moreRead less
Creating a non-invasive window into the mind. This project aims to create better tools to study the human mind. This project expects to generate new knowledge that can be used to non-invasively image neuronal activity. Expected outcomes include the development of unique new Magnetic Resonance Imaging (MRI) instruments to study neuronal activity in both highly controlled laboratory conditions and in humans, with the spatial and temporal resolution needed to study the neuronal circuitry that drive ....Creating a non-invasive window into the mind. This project aims to create better tools to study the human mind. This project expects to generate new knowledge that can be used to non-invasively image neuronal activity. Expected outcomes include the development of unique new Magnetic Resonance Imaging (MRI) instruments to study neuronal activity in both highly controlled laboratory conditions and in humans, with the spatial and temporal resolution needed to study the neuronal circuitry that drives low and high-level brain functions, i.e., creating a window into the mind. In the future, outcomes from this study could improve our understanding of mental disorders, advance computer brain interface technology, and inspire the next paradigm shift in artificial intelligence.Read moreRead less
A Biologically Responsive and Anatomically Authentic Human Nasal Model. As respiratory conditions caused by pollutants and viruses become more prevalent, human nasal models to study infection/protection mechanisms and nasal drug/vaccine delivery are increasingly important. This project aims to develop a world-first human nasal model to mimic both anatomical and biological aspects of the nasal cavity and predict the distribution and deposition of fine particles and the resultant biological respon ....A Biologically Responsive and Anatomically Authentic Human Nasal Model. As respiratory conditions caused by pollutants and viruses become more prevalent, human nasal models to study infection/protection mechanisms and nasal drug/vaccine delivery are increasingly important. This project aims to develop a world-first human nasal model to mimic both anatomical and biological aspects of the nasal cavity and predict the distribution and deposition of fine particles and the resultant biological response from the nasal mucosa. The aim is to overcome a key fabrication challenge - to 3D print an anatomically accurate nasal construct with a porous wall on which to grow and mature functional nasal tissue that lines a nasal cavity wall. The benefit would be enabling faster development of more targeted drugs and vaccines.Read moreRead less
From shape to function: how structured RNA defines insect flaviviruses. The goal of this project is to obtain an understanding of how insect-specific flaviviruses (ISFs) utilise viral noncoding RNAs to enable their replication in mosquitoes. These viruses only replicate in mosquitoes, and not in humans or animals. They can be employed as the biocontrol agents for mosquito-borne diseases as they make mosquitoes incapable of disease transmission. However, it is currently unknown how exactly insect ....From shape to function: how structured RNA defines insect flaviviruses. The goal of this project is to obtain an understanding of how insect-specific flaviviruses (ISFs) utilise viral noncoding RNAs to enable their replication in mosquitoes. These viruses only replicate in mosquitoes, and not in humans or animals. They can be employed as the biocontrol agents for mosquito-borne diseases as they make mosquitoes incapable of disease transmission. However, it is currently unknown how exactly insect-specific flaviviruses affect mosquitoes and this information is vital for informed design of ISF-based interventions. The project will generate new knowledge on functions of noncoding RNAs in ISFs that are hypothesised to have immunomodulatory role in mosquitoes. It will also train students and ECRs.Read moreRead less
A Micro-Physiological System to Mimic Human Microbiome-Organ Interactions. This project aims to mimic gut microbiome-organ interactions by developing a microbial-gut coculture chip, which can reversibly interface with other organs-on-chips. This is achieved through the systematic integration of highly customisable biofabrication and microfluidic technologies. This project fills a critical technological gap in the availability of an animal-alternative system to investigate microbiome-host interac ....A Micro-Physiological System to Mimic Human Microbiome-Organ Interactions. This project aims to mimic gut microbiome-organ interactions by developing a microbial-gut coculture chip, which can reversibly interface with other organs-on-chips. This is achieved through the systematic integration of highly customisable biofabrication and microfluidic technologies. This project fills a critical technological gap in the availability of an animal-alternative system to investigate microbiome-host interactions, which will greatly complement existing meta-omics approaches. The deliverables include a proof-of-concept system validated for gut-liver axis as well as the creation of new knowledge and framework to assimilate design thinking and advanced manufacturing to elevate tissue engineering into physiology engineering. Read moreRead less
Reducing health disparities for culturally and linguistically diverse peoples. This project aims to develop a greater understanding of migrants and the factors that predict poor health outcomes related to blood-borne viruses and sexually transmitted infections. The delayed access by migrants to healthcare from culturally and linguistically diverse backgrounds results in late diagnosis, low treatment uptake, and poorer health outcomes, with enhanced risk of infection and increased burden on the h ....Reducing health disparities for culturally and linguistically diverse peoples. This project aims to develop a greater understanding of migrants and the factors that predict poor health outcomes related to blood-borne viruses and sexually transmitted infections. The delayed access by migrants to healthcare from culturally and linguistically diverse backgrounds results in late diagnosis, low treatment uptake, and poorer health outcomes, with enhanced risk of infection and increased burden on the health system. The data collected in this project will assist in developing health services to meet these needs.Read moreRead less
Biomass-derived Carbon Dots Enable Flexible, On-Demand Hydrogen Delivery . Methanol is a promising liquid hydrogen carrier for long distance H2 transportation and exportation, because it is rich in hydrogen content, cheap, recyclable between methanol-formaldehyde and easier to manufacture from renewable resources including biomass waste. The critical bottleneck in adopting methanol as the carrier is the demanding dehydrogenation process. The project aims to create a new class of photocatalyst ba ....Biomass-derived Carbon Dots Enable Flexible, On-Demand Hydrogen Delivery . Methanol is a promising liquid hydrogen carrier for long distance H2 transportation and exportation, because it is rich in hydrogen content, cheap, recyclable between methanol-formaldehyde and easier to manufacture from renewable resources including biomass waste. The critical bottleneck in adopting methanol as the carrier is the demanding dehydrogenation process. The project aims to create a new class of photocatalyst based on biomass-derived carbon nanodots grown on transition metal (di)chalcogenide nanosheets that can effectively enable a light-controlled methanol H2 release of desired quantity. The key outcomes will be a new class of photocatalysts and flexible, on-demand hydrogen delivery technology for liquid hydrogen carriers.Read moreRead less
Why certain viruses don't get along in mosquitoes. The molecular mechanism. The overall goal of this project is to obtain an understanding of how certain insect-only viruses make mosquitoes incapable of transmitting diseases. These viruses, called insect-specific flaviviruses, can be employed as biocontrol agents for mosquito-borne human and veterinary diseases. However as it is currently unknown how exactly they affect mosquitoes, the safety and efficacy of their use can't be predicted. The pro ....Why certain viruses don't get along in mosquitoes. The molecular mechanism. The overall goal of this project is to obtain an understanding of how certain insect-only viruses make mosquitoes incapable of transmitting diseases. These viruses, called insect-specific flaviviruses, can be employed as biocontrol agents for mosquito-borne human and veterinary diseases. However as it is currently unknown how exactly they affect mosquitoes, the safety and efficacy of their use can't be predicted. The proposed project will dissect the very intricate mechanisms of interactions between insect-specific flaviviruses and mosquitoes and explain how exactly they prevent disease transmission. It should generate novel fundamental knowledge, implement innovative methodologies and provide training for students and junior scientist. Read moreRead less
Solar rechargeable batteries for wearable electronics. This project aims to develop a new solar battery as a sustainable power source for future wearable electronics. The research will develop solar rechargeable Zinc-Manganese oxide batteries based on new stretchable microelectrodes and materials engineering for the direct storage of solar energy. Expected outcomes include new classes of planar-type solar batteries, functional microelectrodes and energy materials, as well as new knowledge genera ....Solar rechargeable batteries for wearable electronics. This project aims to develop a new solar battery as a sustainable power source for future wearable electronics. The research will develop solar rechargeable Zinc-Manganese oxide batteries based on new stretchable microelectrodes and materials engineering for the direct storage of solar energy. Expected outcomes include new classes of planar-type solar batteries, functional microelectrodes and energy materials, as well as new knowledge generated from collaborations across materials science, photoelectrochemistry and nanotechnology disciplines. These will not only expand the applications of solar batteries to a new domain of wearable electronics, but also may eventually lead to new industry advances in functional materials for clean energy.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL220100082
Funder
Australian Research Council
Funding Amount
$3,450,896.00
Summary
My Air Space: the Science of Buildings that Make us Thrive. Nothing is more necessary in human life than the air we breathe, mostly indoors where air quality has been relatively overlooked. This project aims to deliver new science and technology as a foundation for optimising indoor atmospheres to improve health, wellbeing, and comfort. Expected outcomes include innovative, efficient, low-cost diagnostic sensing of indoor atmospheres and human–space interactions, real-time detection of airborne ....My Air Space: the Science of Buildings that Make us Thrive. Nothing is more necessary in human life than the air we breathe, mostly indoors where air quality has been relatively overlooked. This project aims to deliver new science and technology as a foundation for optimising indoor atmospheres to improve health, wellbeing, and comfort. Expected outcomes include innovative, efficient, low-cost diagnostic sensing of indoor atmospheres and human–space interactions, real-time detection of airborne pathogens and particles that host them, and cost-effective localised conditioning of spaces for comfort at points of actual use. Benefits should be seen in areas of health, productivity, reduced energy use, and new industries for the design, modernising, and operation of buildings across Australia and beyond.Read moreRead less