Touch and Tension: Molecular Determinants of Human Mechanosensation . Feelings of touch and muscle tension are initiated by mechanosensory neurons found within the peripheral nervous system. Knowledge of human mechanosensory neurons has predominantly relied on rodent studies because of the limited availability of human tissue, which is not ideal. Our team has developed novel technologies for generating human mechanosensory neurons ‘in the dish’. The major aim of this project is to use human stem ....Touch and Tension: Molecular Determinants of Human Mechanosensation . Feelings of touch and muscle tension are initiated by mechanosensory neurons found within the peripheral nervous system. Knowledge of human mechanosensory neurons has predominantly relied on rodent studies because of the limited availability of human tissue, which is not ideal. Our team has developed novel technologies for generating human mechanosensory neurons ‘in the dish’. The major aim of this project is to use human stem cell-derived mechanosensory neurons as a platform to extensively study their molecular and functional properties. The significant benefits are the advancement of knowledge in the human mechanosensory system, which to date has been lacking, and in the long-term progress commercial development of novel drugs.Read moreRead less
Novel nanostructured high energy cathode material. Recently, the demand for rechargeable batteries has exploded due to the enormous increase in the variety and number of miniaturized devices. It is expected that this demand for high capacity rechargeable batteries as energy sources will become even greater in the future. This program is focused to develop novel high performance cathode materials for lithium rechargeable batteries. The outcomes of the project will be of great benefit to develop ....Novel nanostructured high energy cathode material. Recently, the demand for rechargeable batteries has exploded due to the enormous increase in the variety and number of miniaturized devices. It is expected that this demand for high capacity rechargeable batteries as energy sources will become even greater in the future. This program is focused to develop novel high performance cathode materials for lithium rechargeable batteries. The outcomes of the project will be of great benefit to develop new class rechargeable batteries that are economical, lightweight, environmentlly benign and high energy.Read moreRead less
Structural safety guidelines for accidental hydrogen explosion hazards . This project aims to develop structural safety guidelines to mitigate hydrogen explosion hazards which can be identified as a major safety concern due to the higher demand worldwide for sustainable energy sources with no carbon emission. The world’s growing demand for hydrogen and Australia’s National Hydrogen Strategy to develop the industry will make Australia a core player in hydrogen production creating a massive econom ....Structural safety guidelines for accidental hydrogen explosion hazards . This project aims to develop structural safety guidelines to mitigate hydrogen explosion hazards which can be identified as a major safety concern due to the higher demand worldwide for sustainable energy sources with no carbon emission. The world’s growing demand for hydrogen and Australia’s National Hydrogen Strategy to develop the industry will make Australia a core player in hydrogen production creating a massive economic opportunity. However, the high flammability and low ignition energy of hydrogen makes it vulnerable to accidental explosions. Hence, this project will address the lack of safety protocols in Australian Standards related to the handling of hydrogen by producing essential design recommendations.Read moreRead less
Inequality, Prosperity and the Australian Welfare State. This project aims to clarify contested understandings of Australian inequality and the role of economic and social policies in addressing policy challenges going forward. The objective of the project is to generate significantly improved knowledge of inequality in Australia using innovative approaches of data splicing, decomposition, simulation and backcasting to fill research gaps and resolve contested interpretations. We aim to provide a ....Inequality, Prosperity and the Australian Welfare State. This project aims to clarify contested understandings of Australian inequality and the role of economic and social policies in addressing policy challenges going forward. The objective of the project is to generate significantly improved knowledge of inequality in Australia using innovative approaches of data splicing, decomposition, simulation and backcasting to fill research gaps and resolve contested interpretations. We aim to provide a benchmark and robust framework against which policy development after the current crisis can be evaluated. This project aims to provide significant benefits, keeping Australia at the forefront of research on inequality and public policy, strengthening links between researchers and policy makers.
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Integrable Functional and Delay Differential Equations. Major challenges such as predicting epidemics or modelling the dynamics of human movement, rely on our understanding of functional and delay differential equations. This research will provide new methods for prediction and analysis of such models.
Child poverty, labour markets and social transfers. This project aims to discover how earnings and social transfers determine the living standards of disadvantaged families with children, and the constraints that wage rates and employment patterns place on social transfer structures. This project will compare the family incomes of disadvantaged children and how the interaction of wage rates, employment and social policies affect them. It will compare Australian outcomes to those in OECD and midd ....Child poverty, labour markets and social transfers. This project aims to discover how earnings and social transfers determine the living standards of disadvantaged families with children, and the constraints that wage rates and employment patterns place on social transfer structures. This project will compare the family incomes of disadvantaged children and how the interaction of wage rates, employment and social policies affect them. It will compare Australian outcomes to those in OECD and middle income countries. This project expects to understand which labour market and social policies combine to lead to the best economic outcomes for disadvantaged families and children.Read moreRead less
Allocating scarce HIV/AIDS antiretroviral drugs in resource-constrained countries: using modelling to develop tools and analyse consequences of ethics and HIV-epidemiology. This project will benefit communities in some of the poorest countries of the world, suffering greatly from the HIV/AIDS epidemic. This research is important and timely for these nations in deciding how to distribute the limited treatment in an ethical manner to address treatment principles of these countries. However, the me ....Allocating scarce HIV/AIDS antiretroviral drugs in resource-constrained countries: using modelling to develop tools and analyse consequences of ethics and HIV-epidemiology. This project will benefit communities in some of the poorest countries of the world, suffering greatly from the HIV/AIDS epidemic. This research is important and timely for these nations in deciding how to distribute the limited treatment in an ethical manner to address treatment principles of these countries. However, the methods developed can also be applied to other diseases in different regions and people, such as Australian aborigines to increase their quality of health. Specifically, an epidemic of Chlamydia is widespread amongst the aboriginal communities of Australia's Northern Territory. Tools developed in this project will be easily adaptable to address control measures for Chlamydia among this population. Read moreRead less
Understanding spatial trends in HIV/AIDS infections in South Africa and Australia. This project will develop quantitative methods that will be used to inform public health officials in understanding past and current HIV/AIDS epidemics as well as planning for the future of these epidemics. It will understand not only the behavioural and demographic characteristics of importance as risk factors for HIV infection in South Africa, the epicentre of the global HIV pandemic, but also the geographical s ....Understanding spatial trends in HIV/AIDS infections in South Africa and Australia. This project will develop quantitative methods that will be used to inform public health officials in understanding past and current HIV/AIDS epidemics as well as planning for the future of these epidemics. It will understand not only the behavioural and demographic characteristics of importance as risk factors for HIV infection in South Africa, the epicentre of the global HIV pandemic, but also the geographical spatial locations in which HIV cases are likely to emerge in the future. This project will also forecast the future geographical trends in Australia's changing HIV epidemic in order to plan for intervention strategies and prepare clinical practice appropriately.Read moreRead less
Evolutionary models and bioinformatic analyses of genetic variation in pathogens. The benefits of this project are better preparedness for the ever-present threat of infectious disease spread and the stimulation of bioinformatic research in Australia. Epidemics such as the Influenza Pandemic of 1918, which killed over 20 million people, highlight the need to understand and track pathogens that can potentially cause such devastation. Along with the development of molecular technologies, it is imp ....Evolutionary models and bioinformatic analyses of genetic variation in pathogens. The benefits of this project are better preparedness for the ever-present threat of infectious disease spread and the stimulation of bioinformatic research in Australia. Epidemics such as the Influenza Pandemic of 1918, which killed over 20 million people, highlight the need to understand and track pathogens that can potentially cause such devastation. Along with the development of molecular technologies, it is important to maintain active creation of analytical methods that appropriately apply to growing databases. These include methods to understand genetic variation in pathogens. This project will help to keep Australia at the forefront of research in theoretical biology.Read moreRead less
Advanced Nanostructured Ceramic Composites for Ultracapacitors. The global climate changes and the related disastrous events such as heat flows, bushfires, and flooding will endanger the Australian population and our natural environment. The implementation of effective devices and technologies to reduce our carbon footprint is a priority task. The project addresses the issue by development of new ultracapacitor materials for next generation green energy storage devices through engineering and im ....Advanced Nanostructured Ceramic Composites for Ultracapacitors. The global climate changes and the related disastrous events such as heat flows, bushfires, and flooding will endanger the Australian population and our natural environment. The implementation of effective devices and technologies to reduce our carbon footprint is a priority task. The project addresses the issue by development of new ultracapacitor materials for next generation green energy storage devices through engineering and implementation of advanced nanoceramics and nanocomposites created by innovative nanotechnologies. The project will also contribute to other national research priorities such as materials and frontier technologies, reduction of atmospheric pollution, and decrease in the energy dependence of our country on oil.Read moreRead less