Novel Methods For Promoting Organ Development And Growth
Funder
National Health and Medical Research Council
Funding Amount
$390,203.00
Summary
A revolutionary new therapy for treatment of growth restricted fetuses and premature babies is being developed through the administration of Colony Stimulating Factor (CSF-1). We have evidence that CSF-1 therapy can promote kidneys and lungs to continue development and maturation after birth. This exciting new finding allows for the application of CSF-1 therapy for both the treatment of premature babies and unborn babies with kidney defects.
Understanding The Causes Of Childhood Congenital Anomalies Of The Kidney And Urinary Tract
Funder
National Health and Medical Research Council
Funding Amount
$609,748.00
Summary
Congenital anomalies of the kidney and urinary tract (CAKUT) is a common cause of renal failure in children. The majority of patients with CAKUT do not know the underlying cause of their renal anomalies. In this proposal we will characterise the developmental events that are perturbed in three mouse models of CAKUT and identify the causal gene responsible in each mouse model. We will translate this information to the clinic by screening patients with CAKUT for mutations in these newly identified ....Congenital anomalies of the kidney and urinary tract (CAKUT) is a common cause of renal failure in children. The majority of patients with CAKUT do not know the underlying cause of their renal anomalies. In this proposal we will characterise the developmental events that are perturbed in three mouse models of CAKUT and identify the causal gene responsible in each mouse model. We will translate this information to the clinic by screening patients with CAKUT for mutations in these newly identified genes.Read moreRead less
Special Research Initiatives - Grant ID: SR0354622
Funder
Australian Research Council
Funding Amount
$20,000.00
Summary
Genes and Environment in Development. Interactions between the early environment and the genetic regulatory program of the early embryo have major consequences for the development of individuals. The aim of this Network is to harness the resources of leading researchers from the previously distinct disciplines of developmental biology and developmental physiology to better understand developmental regulatory networks and how environmental factors impinge on them. The formation of such a Network ....Genes and Environment in Development. Interactions between the early environment and the genetic regulatory program of the early embryo have major consequences for the development of individuals. The aim of this Network is to harness the resources of leading researchers from the previously distinct disciplines of developmental biology and developmental physiology to better understand developmental regulatory networks and how environmental factors impinge on them. The formation of such a Network is unique, timely and strategic in that it will generate new insights into the mechanisms by which events in early life determine the risk of adverse outcomes in perinatal and adult life.Read moreRead less
ARC/NHMRC Research Network in Genes and Environment in Development. Interactions between the early environment and the genetic regulatory program of the developing organism have major consequences for the lifetime health of individuals. The primary objective of the Network in Genes and Environment in Development is to harness the resources of leading researchers from the currently distinct disciplines of developmental biology and developmental physiology to define key developmental regulatory ne ....ARC/NHMRC Research Network in Genes and Environment in Development. Interactions between the early environment and the genetic regulatory program of the developing organism have major consequences for the lifetime health of individuals. The primary objective of the Network in Genes and Environment in Development is to harness the resources of leading researchers from the currently distinct disciplines of developmental biology and developmental physiology to define key developmental regulatory networks and to address how environmental factors impinge on these regulatory networks. The formation of this National Research Network is unique, timely and strategic. It will generate new insights into the mechanisms by which events in early life determine the risk of adverse outcomes in perinatal and adult life.Read moreRead less
Understanding and Managing the Occupational Health Impacts on Investigators of Internet Child Exploitation. Through developing best practice models for managing vicarious trauma in investigators of Internet child exploitation, the project will result in enhanced job satisfaction and less burnout of workers, and reduced health costs for policing organisations. Thus the project addresses a serious occupational health issue and contributes to the goal of promoting and maintaining good health. Furth ....Understanding and Managing the Occupational Health Impacts on Investigators of Internet Child Exploitation. Through developing best practice models for managing vicarious trauma in investigators of Internet child exploitation, the project will result in enhanced job satisfaction and less burnout of workers, and reduced health costs for policing organisations. Thus the project addresses a serious occupational health issue and contributes to the goal of promoting and maintaining good health. Further, by better managing the occupational health of investigators, the project will enhance the capacity of police organisations to deliver on their mission of investigating and preventing Internet child exploitation. This in turn contributes to the reduced consumption of Internet child exploitation and the associated traumatisation of abused victims. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0561030
Funder
Australian Research Council
Funding Amount
$441,100.00
Summary
Developmental Imaging Facility. This application seeks to establish a facility to undertake expression profiling in vertebrate tissues on a genomic scale and at the highest resolution. Undertaking large scale projects of this nature requires specialised robotics and dedicated infrastructure for microscopy and tissue preparation. This facility will be the first of its type in Australia will permit researchers to perform genomic scale in situ screens, many as part of large international initiative ....Developmental Imaging Facility. This application seeks to establish a facility to undertake expression profiling in vertebrate tissues on a genomic scale and at the highest resolution. Undertaking large scale projects of this nature requires specialised robotics and dedicated infrastructure for microscopy and tissue preparation. This facility will be the first of its type in Australia will permit researchers to perform genomic scale in situ screens, many as part of large international initiatives in developmental and cellular biology. This large-scale, high-resolution expression profiling infrastructure is required to maintain international competitiveness and will dramatically improve our gene discovery, functional assessment and understanding of vertebrate development.Read moreRead less
Predicting health, well-being, and educational success in emerging adults: An 8 year longitudinal study. This project will inform the community about factors that affect the psychological, physical, academic, and employment outcomes of emerging adults. It will improve our knowledge of why some young people do not reach their full potential. The project will provide a comprehensive assessment of factors associated with well-being across several domains. It will better equip and assist professiona ....Predicting health, well-being, and educational success in emerging adults: An 8 year longitudinal study. This project will inform the community about factors that affect the psychological, physical, academic, and employment outcomes of emerging adults. It will improve our knowledge of why some young people do not reach their full potential. The project will provide a comprehensive assessment of factors associated with well-being across several domains. It will better equip and assist professionals to identify early those youth at risk of having poor psychological, health, and employment prospects post-school. The project will inform the development of intervention programs for young people and maximise their overall adjustment and well-being several years later.Read moreRead less
Addressing the teacher exodus: Enhancing early career teacher resilience and retention in changing times. This research will produce new knowledge, strategies, models and recommendations that will help to keep early career teachers in the profession in regional, rural and remote areas. In doing so it will address the problem of teacher shortage that is currently threatening the nation's educational, economic and social outcomes. The research outcomes will have particular credibility at the natio ....Addressing the teacher exodus: Enhancing early career teacher resilience and retention in changing times. This research will produce new knowledge, strategies, models and recommendations that will help to keep early career teachers in the profession in regional, rural and remote areas. In doing so it will address the problem of teacher shortage that is currently threatening the nation's educational, economic and social outcomes. The research outcomes will have particular credibility at the national level because they will be the result of dialogue and collaboration across three universities and six industry partners who are the key stakeholders in teacher employment in two states. In addition, the collaborative approach will facilitate implementation of recommendations at the local, state and national levels.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0347122
Funder
Australian Research Council
Funding Amount
$200,000.00
Summary
Australian Women's Archives Project (AWAP). Australian Women's Archives Project aims to enhance infrastructure for researchers in the field of women's and gender history by constructing appropriate data bases and a range of other electronic sources of information, and by improving the preservation and accessibility of records and archives relevant to this prominent and growing field. Project outcomes will include support for the production of cutting edge academic historical works and simultaneo ....Australian Women's Archives Project (AWAP). Australian Women's Archives Project aims to enhance infrastructure for researchers in the field of women's and gender history by constructing appropriate data bases and a range of other electronic sources of information, and by improving the preservation and accessibility of records and archives relevant to this prominent and growing field. Project outcomes will include support for the production of cutting edge academic historical works and simultaneously, the significant contribution of an essential information resource base for Australian women.
The Australian Women's Archives Project employs innovative technologies and adheres to state-of-the-art international standards for electronic management of historical information. The roles of AWAP's Chief Investigators reflect the use of these new forms of information management: CIs both create and utilise the products of each others' collaborative historical research.
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Special Research Initiatives - Grant ID: SR0354677
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Sustainable terrestrial and riverine systems through integrated assessment and modelling. Australia must take the lead internationally in sustainability assessment and management; it hosts both the problems and expertise, and is proactive in integrating research and management. This Initiative unites, for the first time, leading researchers from all relevant disciplines to advance our knowledge for achieving sustainable terrestrial and riverine systems (STARS). The intended network can produce a ....Sustainable terrestrial and riverine systems through integrated assessment and modelling. Australia must take the lead internationally in sustainability assessment and management; it hosts both the problems and expertise, and is proactive in integrating research and management. This Initiative unites, for the first time, leading researchers from all relevant disciplines to advance our knowledge for achieving sustainable terrestrial and riverine systems (STARS). The intended network can produce assessments, strategies and policy directions that are objective, adaptive and inclusive. It can evaluate trade-offs between sustainability strategies, integrating research and outcomes, making them accessible to managers. It will build a coordinated research capability that directly supports Australia's goal of ecologically sustainable development. Read moreRead less