Role Of Tenascin-C And TLR-4 In Carotid Atherosclerosis Related Stroke
Funder
National Health and Medical Research Council
Funding Amount
$308,071.00
Summary
It is estimated that approximately 10,000 Australians per year suffer from strokes related to neck artery disease. Warning signs often go undiagnosed and unreported. Currently there are no blood tests available for early simple diagnosis and few specific drugs available to reduce the number of strokes. Based on preliminary studies we will investigate the role of a novel protein and its related pathway in stroke. We will also study the value of these proteins as a blood test for this problem.
Cerebrovascular Diseases And Brain Ageing – A Program Of Research Into Novel Mechanisms, Risk Prevention And Innovative Health Care Delivery
Funder
National Health and Medical Research Council
Funding Amount
$466,492.00
Summary
This research is aimed at understanding the ways in which age-related vascular disease affecting the brain leads to walking difficulty, cognitive impairment and falls in older people. It is also designed to discover potentially modifiable risk factors for such vascular disease. Ultimately the goal of this research is to design and conduct trials of interventions aimed at slowing the process of vascular brain ageing.
An International Comparison Of Systems Of Care, Risk Stratification And Outcomes In TIA And Minor Stroke
Funder
National Health and Medical Research Council
Funding Amount
$1,189,790.00
Summary
Transient ischaemic attacks (TIAs: self-limited brief episodes of stroke symptoms) are high-risk events with an approximately 15% risk of stroke within 90-days. Current practice calls for specialist treatment within 1-7 days. But this recommendation (based on 20 year old overseas evidence) may not apply in contemporary Australia. We will conduct a study of patients with TIA that will document their interactions with Australian health systems and inform contemporary Australian practice.