Understanding Causes Of The Rising Incidence Of Thyroid Cancer – What Can Mutations In The BRAF Oncogene Tell Us About Causes And Diagnostic Pathways For Thyroid Cancer?
Funder
National Health and Medical Research Council
Funding Amount
$610,222.00
Summary
The occurrence of thyroid cancer has increased rapidly over the last 25 years but the cause is unknown. The increase may reflect ‘over-diagnosis’ of less harmful cancers or greater exposure to causes of this cancer. Evidence suggests that a gene mutation (BRAF) in thyroid cancers is important in understanding the drivers of the increase. This study will examine the increase in thyroid cancer by investigating causes and diagnostic pathways considering the presence or absence of BRAF mutations.
Improving Cancer Outcomes In Under-studied Cancers By Understanding Their Risk Factors And Patterns Of Cancer Care.
Funder
National Health and Medical Research Council
Funding Amount
$421,747.00
Summary
Cancer is the second leading cause of disease burden in Australia. Much can be done to reduce this burden through effective cancer prevention and ensuring all patients receive optimal evidence-based care. This research focuses on thyroid, kidney and ovarian cancer and aims to increase knowledge of these cancers’ causes and to investigate variation in patient care and its impact on outcomes. Ultimately the objective of the work is to decrease Australia’s cancer burden.
Infant Thyroid Hormone Levels And Long-term Child Educational Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$149,782.00
Summary
Adequate levels of newborn thyroid hormones are essential for brain development.Newborn screening for thyroid hormone deficiency ensures early identification, treatment & prevention of severe intellectual disability.But there is clinical uncertainty in mildly abnormal levels.We will assess thyroid hormone levels & subsequent educational outcomes in 1.5M Australian babies.There is potential to identify infants who, without treatment, may suffer longterm disability & lower educational achievement
Infant Thyroid Hormone Levels And Long-term Child Educational Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$490,495.00
Summary
Adequate levels of newborn thyroid hormones are essential for brain development.Newborn screening for thyroid hormone deficiency ensures early identification, treatment & prevention of severe intellectual disability.But there is clinical uncertainty in mildly abnormal levels.We will assess thyroid hormone levels & subsequent educational outcomes in 1.5M Australian babies.There is potential to identify infants who, without treatment, may suffer longterm disability & lower educational achievement
Sun Exposure, Vitamin D And Photohealth Over The Lifetime
Funder
National Health and Medical Research Council
Funding Amount
$622,655.00
Summary
Australia is a sunny country with a diverse population. Inappropriate sun exposure for skin type leads to skin cancer (mainly in the fair-skinned) and vitamin D deficiency (particularly in the darker-skinned). Potential benefits of sun exposure are broader than vitamin D production, but remain ill-defined. There are few data on appropriate sun exposure for children. This research fellowship builds the evidence to guide sun exposure messages.