Design and Development of a Low-Cost Portable Biofeedback Device for use in Sleep Induction and Relaxation. This project aims to expand on existing knowledge of the various stimuli used in sleep induction such as photic, auditory and weak electromagnetic stimulation and develop a low-cost portable biofeedback prototype. This novel device will be based on adaptive or fuzzy reasoning algorithms, which would be integrated into the existing ambulatory Siesta EEG recording system, produced by Compume ....Design and Development of a Low-Cost Portable Biofeedback Device for use in Sleep Induction and Relaxation. This project aims to expand on existing knowledge of the various stimuli used in sleep induction such as photic, auditory and weak electromagnetic stimulation and develop a low-cost portable biofeedback prototype. This novel device will be based on adaptive or fuzzy reasoning algorithms, which would be integrated into the existing ambulatory Siesta EEG recording system, produced by Compumedics Ltd. The development of this novel real-time biofeedback prototype will encourage further research using this particular technology to apply it in preventative healthcare in Australian community. The outcome of this proposed bioinstrumentation prototype could possibly expand sleep market to new international level.Read moreRead less
Drug particle characterisation. The understanding of drug particle characterizations is one of the key issues in the development of novel nasal sprayers for targeted drug delivery. A comprehensive study is proposed for characterising drug formation in sprayers and particle deposition in nasal cavity using the latest experimental and numerical techniques. A computer-aided design technology will be developed to optimise drug delivery systems. The new technology has great potentials leading to the ....Drug particle characterisation. The understanding of drug particle characterizations is one of the key issues in the development of novel nasal sprayers for targeted drug delivery. A comprehensive study is proposed for characterising drug formation in sprayers and particle deposition in nasal cavity using the latest experimental and numerical techniques. A computer-aided design technology will be developed to optimise drug delivery systems. The new technology has great potentials leading to therapeutic and economic benefits in developing advanced/innovative drug delivery systems and in evaluating the potential biological effects by the drugs to be introduced through the nose.Read moreRead less
OPTIMIZED NASAL DRUG DELIVERY SYSTEMS -- COMPUTER AIDED DESIGN. The aim of this project is to develop a computer-aided design technology to assist in targeted drug delivery through the human nasal cavity which is being recognised to be an excellent alternative route for the administration of medication drugs. The aim will be achieved by conducting computer modelling of nasal flow under realistic physiological conditions and by performing experimental measurements and testing to validate computer ....OPTIMIZED NASAL DRUG DELIVERY SYSTEMS -- COMPUTER AIDED DESIGN. The aim of this project is to develop a computer-aided design technology to assist in targeted drug delivery through the human nasal cavity which is being recognised to be an excellent alternative route for the administration of medication drugs. The aim will be achieved by conducting computer modelling of nasal flow under realistic physiological conditions and by performing experimental measurements and testing to validate computer models. The new technology has great potentials leading to therapeutic and economical benefits in developing advanced/innovative drug delivery systems and in evaluating the potential biological effects by the drugs to be introduced through the nose.Read moreRead less
Combined optical and electrical stimulation of auditory neurons. The bionic ear, which has now helped to improve the hearing of over 200,000 people worldwide, is a great example of Australian innovation success. This project aims to develop the fundamental technology that will underpin the next generation of these devices using a combination of infrared light and electrical signals to stimulate auditory nerves.
Complete blood fractionation using a low-cost microfluidic system. This project aims to understand particle focusing in inertial microfluidic systems to design efficient devices for cell sorting. The field of microfluidics could ultimately advance medical research but device design is primitive. Microfluidic particle separations are not thoroughly simulated before fabrication to predict performance. This project is expected to accelerate progress in design of efficient microfluidic devices. The ....Complete blood fractionation using a low-cost microfluidic system. This project aims to understand particle focusing in inertial microfluidic systems to design efficient devices for cell sorting. The field of microfluidics could ultimately advance medical research but device design is primitive. Microfluidic particle separations are not thoroughly simulated before fabrication to predict performance. This project is expected to accelerate progress in design of efficient microfluidic devices. The knowledge and models developed in this project should help design and develop a microfluidic device for efficient fractionation of complex fluids into valuable components.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE130100922
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Diamond cybernetics: nanocrystalline diamond for interfacing bionic devices with the human nervous system. Bionic devices will soon be used to treat disorders such as epilepsy, Parkinson's and depression. We will use diamond to create high resolution, permanent electrical connections between devices and the human nervous system. These diamond connections will preserve nerve health and make bionic devices more effective and able to last a lifetime.
Quantitative micro-computed tomography for mechanobiological measurement. This project aims to investigate novel measurement approaches for complex cartilage and joint systems by utilising engineering and software design, imaging physics and musculoskeletal biology. Accurate measurement of these living biological systems in action expects to generate new knowledge and a fundamental understanding of their mechanobiological processes. This project will enhance understanding of this complex system ....Quantitative micro-computed tomography for mechanobiological measurement. This project aims to investigate novel measurement approaches for complex cartilage and joint systems by utilising engineering and software design, imaging physics and musculoskeletal biology. Accurate measurement of these living biological systems in action expects to generate new knowledge and a fundamental understanding of their mechanobiological processes. This project will enhance understanding of this complex system and facilitate our capacity to innovate functional solutions in biomedical engineering and biosciences.Read moreRead less
Three-Dimensional Polymer Fibre Scaffolds with Functional Nano-structured Surface. The Partner Organisation to this research, CyGenics Ltd, is a world leader in cell biotechnology. A key challenge faced by the CyGenics and other biotech companies is the provision of tissue scaffolding materials that have the right three-dimensional macroscopic structure plus a suitable nano-structured surface micro-environment, similar to the natural extracellular matrix. This joint project combines expertise in ....Three-Dimensional Polymer Fibre Scaffolds with Functional Nano-structured Surface. The Partner Organisation to this research, CyGenics Ltd, is a world leader in cell biotechnology. A key challenge faced by the CyGenics and other biotech companies is the provision of tissue scaffolding materials that have the right three-dimensional macroscopic structure plus a suitable nano-structured surface micro-environment, similar to the natural extracellular matrix. This joint project combines expertise in polymer fibres, surface engineering and cell culture to tackle the key challenge. The outcome will help position the local polymer fibre and cell culture industries at the forefront of tissue scaffolding materials research and development. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100175
Funder
Australian Research Council
Funding Amount
$347,070.00
Summary
Three-dimensional additive bio-fabrication facility: printing bioprinters. This project aims to develop bioprinting systems that will provide new insights into fundamental biological processes. The 3D Additive Bio-Fabrication Facility - Printing Bioprinters capability will use 3D polymer and metal additive manufacturing technologies to create the next generation of bioprinting methodologies and 3D fabrication tools. It is the aim that these customised additive manufacturing systems will be used ....Three-dimensional additive bio-fabrication facility: printing bioprinters. This project aims to develop bioprinting systems that will provide new insights into fundamental biological processes. The 3D Additive Bio-Fabrication Facility - Printing Bioprinters capability will use 3D polymer and metal additive manufacturing technologies to create the next generation of bioprinting methodologies and 3D fabrication tools. It is the aim that these customised additive manufacturing systems will be used to produce structures wherein living cells are spatially organised in combination with appropriate biomaterials and bioactive components, such as drugs or growth factors, in order to influence subsequent biological behaviour.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE220100302
Funder
Australian Research Council
Funding Amount
$461,300.00
Summary
A long-lasting interface for communicating with the brain. This project aims to address the most urgent challenges in developing the next generation of implantable devices for communicating with the brain. Using a new type of carbon-based electrode, along with light therapy, this project expects to build innovative technologies that can greatly enhance the functionality and longevity of these devices. Expected outcomes include a novel tool that can be implemented to obtain detailed insights into ....A long-lasting interface for communicating with the brain. This project aims to address the most urgent challenges in developing the next generation of implantable devices for communicating with the brain. Using a new type of carbon-based electrode, along with light therapy, this project expects to build innovative technologies that can greatly enhance the functionality and longevity of these devices. Expected outcomes include a novel tool that can be implemented to obtain detailed insights into neural circuits, advancing our understanding of neural function and pioneering feedback and closed-loop neuroscience. This project should provide significant benefits in neuroscience research and the neural interface industry, both of which have the ultimate goal to unlock the mysteries of the brain.Read moreRead less