Information Encoding By Temporal Structure Of Afferent Spike Trains
Funder
National Health and Medical Research Council
Funding Amount
$231,175.00
Summary
Our ability to sense, discriminate and interpret touch stimuli underpins some of the most crucial functions of the human hand that relate to object exploration and manipulation. The fundamental mechanism of how nerve impulses generated by tactile receptors are interpreted by the nervous system is not understood. Only by discovering the underlying neural encoding mechanisms can we appreciate the functional impairments in patients and learn to identify them before they become widespread and irreve ....Our ability to sense, discriminate and interpret touch stimuli underpins some of the most crucial functions of the human hand that relate to object exploration and manipulation. The fundamental mechanism of how nerve impulses generated by tactile receptors are interpreted by the nervous system is not understood. Only by discovering the underlying neural encoding mechanisms can we appreciate the functional impairments in patients and learn to identify them before they become widespread and irreversible.Read moreRead less
Most eye diseases have a genetic contribution, whether rare disorders affecting children such as retinoblastoma or congenital cataracts through to common disorders of older people such as myopia, age-related macular degeneration or glaucoma. We will continue our successful research to find genes that cause these diseases and use this to improve patient care and prevent blindness. We will work out how families can use this genetic information to participate in trials to develop new treatments.
A Multi-national Trial To Predict Treatment Response In Subtypes Of Depression
Funder
National Health and Medical Research Council
Funding Amount
$387,489.00
Summary
Treatment of MDD using trial and error can have serious consequences. It can prolong the patient’s suffering (depression is associated with substantial morbidity, and mortality), prolong their absence from work and other productive activity and increase the burden on their family-carers. This multi-national study will collect genetics, brain function and behavioural data from a large number of participants, allowing for sensitive predictors of response to be determined.
Ablative thermal protection systems. The project will study ablative reentry heat shields by experiments simulating hypervelocity atmospheric flight. The results will enable the design of the advanced spacecraft which are needed to extend mans exploration of the universe. Data will be validated by comparison with flights such as the Japanese Hayabusa asteroid sample return mission.
Rapid Recovery from Radiation-induced Errors in Reconfigurable Hardware. This project aims to develop new methods for implementing satellite-based digital systems using reconfigurable hardware devices. The results aim to extend knowledge on the design of fault-tolerant systems and enable the use of off-the-shelf digital hardware in the implementation of satellite systems. The project aims to develop essential tools to assist in implementing fault-tolerant reconfigurable systems. These tools will ....Rapid Recovery from Radiation-induced Errors in Reconfigurable Hardware. This project aims to develop new methods for implementing satellite-based digital systems using reconfigurable hardware devices. The results aim to extend knowledge on the design of fault-tolerant systems and enable the use of off-the-shelf digital hardware in the implementation of satellite systems. The project aims to develop essential tools to assist in implementing fault-tolerant reconfigurable systems. These tools will be founded on the discovery of techniques needed for modifying a design into a form amenable to error recovery and for implementing the design in hardware. During the course of the project, these techniques will be demonstrated and tested in-orbit on the international QB50 CubeSat program.Read moreRead less
Designing Radiation-Tolerant Reconfigurable Systems for Space. The processing speed, cost and flexibility requirements of future satellite-based applications cannot be satisfied with conventional radiation-hardened processors or custom integrated circuits. This project aims to develop key technology to enable off-the-shelf hardware to be customised for this use without compromising reliability. The project aims to develop the design methods needed to implement a given set of satellite applicatio ....Designing Radiation-Tolerant Reconfigurable Systems for Space. The processing speed, cost and flexibility requirements of future satellite-based applications cannot be satisfied with conventional radiation-hardened processors or custom integrated circuits. This project aims to develop key technology to enable off-the-shelf hardware to be customised for this use without compromising reliability. The project aims to develop the design methods needed to implement a given set of satellite applications on a processing platform composed of application-specific soft processors and accelerator circuits hosted on conventional reconfigurable logic devices. Crucially, the solution architecture is expected to be sufficiently hardened against radiation-induced errors while meeting performance and circuit area constraints.Read moreRead less