Nanoarchitectured multifunctional porous superparamagnetic nanoparticles. This project aims to develop a method for the direct detection of biomarkers based on a new class of highly porous superparamagnetic nanoparticles with peroxidase-like activity. The particles will be used as dispersible capture agents for isolating specific targets in biological samples, and electrocatalytic nanozymes for naked-eye evaluation and electrochemical detection. The project is expected to develop simple, low-cos ....Nanoarchitectured multifunctional porous superparamagnetic nanoparticles. This project aims to develop a method for the direct detection of biomarkers based on a new class of highly porous superparamagnetic nanoparticles with peroxidase-like activity. The particles will be used as dispersible capture agents for isolating specific targets in biological samples, and electrocatalytic nanozymes for naked-eye evaluation and electrochemical detection. The project is expected to develop simple, low-cost, portable devices for the analysis of exosomes and exosomal miRNA in biological samples. The future development of this technology into diagnostic devices will improve patient outcomes by enabling earlier disease diagnosis and improved monitoring of treatment.Read moreRead less
Single molecule sensing on nanopillars: Reading complex molecular circuits. This project aims to develop an entirely new nanotechnology to visualise dynamic molecular circuits in real time, and within any biological sample as small as a single cell. This project expects to generate new knowledge in the field of cell biology and sensor technology, using innovative nanofabrication and nanoscopic fluid flows to advance understanding of the emerging field of single protein molecule interactions in c ....Single molecule sensing on nanopillars: Reading complex molecular circuits. This project aims to develop an entirely new nanotechnology to visualise dynamic molecular circuits in real time, and within any biological sample as small as a single cell. This project expects to generate new knowledge in the field of cell biology and sensor technology, using innovative nanofabrication and nanoscopic fluid flows to advance understanding of the emerging field of single protein molecule interactions in cellular pathways. Expected outcomes include a universal technology platform to detect single molecules in single cells, with potential to deliver valuable intellectual property of commercial interest and economic benefit through technological advancements.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE210101666
Funder
Australian Research Council
Funding Amount
$395,588.00
Summary
Engineering nanoparticles with enhanced adhesion at the nano-bio interfaces. This project aims to develop a next-generation adhesive nanoparticle platform through in-depth understandings of nanoparticle interactions with bio-interfaces. This project expects to generate new knowledge in the multidisciplinary research field at nano-bio-interfaces by using a recently developed nano-colloidal probe technology, instructing the rational design of nanoparticles with enhanced interface adhesive properti ....Engineering nanoparticles with enhanced adhesion at the nano-bio interfaces. This project aims to develop a next-generation adhesive nanoparticle platform through in-depth understandings of nanoparticle interactions with bio-interfaces. This project expects to generate new knowledge in the multidisciplinary research field at nano-bio-interfaces by using a recently developed nano-colloidal probe technology, instructing the rational design of nanoparticles with enhanced interface adhesive properties. Expected outcomes include a family of adhesive nanoparticles designed for nanopesticide and animal feed applications, with the potential to deliver valuable intellectual property of commercial interest and economic benefit through technology advancement.Read moreRead less
A New Platform of Bio-inspired Nanoparticles for Enhanced Cellular Delivery. Delivery of various molecules into cells is crucial in modern medicine. Compared to viral vectors, non-viral vectors are safer delivery vehicles, but their delivery efficiency must be improved before they can be broadly used. Inspired by the surface topography of viruses with high infectivity, this project aims to provide a fundamental understanding of the impact of surface roughness on cellular delivery efficiency; and ....A New Platform of Bio-inspired Nanoparticles for Enhanced Cellular Delivery. Delivery of various molecules into cells is crucial in modern medicine. Compared to viral vectors, non-viral vectors are safer delivery vehicles, but their delivery efficiency must be improved before they can be broadly used. Inspired by the surface topography of viruses with high infectivity, this project aims to provide a fundamental understanding of the impact of surface roughness on cellular delivery efficiency; and to use this knowledge in the designed synthesis of a new family of bio-inspired non-viral nanoparticles with both safety and high cellular delivery efficiency. The new and high performance nano-carriers will become a platform technology with broad bio-applications in gene therapy, cancer therapy and bio-imaging.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160100796
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Superior Adsorption Capability of Nanosheets for Surface Enhanced Raman. This project aims to create nanotechnologies to sense traces of chemical and biological molecules. Surface adsorption is vital to many scientific and industrial fields, but the intrinsic adsorption property of two-dimensional nanomaterials is largely unknown. This project aims to examine the adsorption capability of nanosheets, such as boron nitride, and understand the thickness effect on their adsorption at the molecular s ....Superior Adsorption Capability of Nanosheets for Surface Enhanced Raman. This project aims to create nanotechnologies to sense traces of chemical and biological molecules. Surface adsorption is vital to many scientific and industrial fields, but the intrinsic adsorption property of two-dimensional nanomaterials is largely unknown. This project aims to examine the adsorption capability of nanosheets, such as boron nitride, and understand the thickness effect on their adsorption at the molecular scale. It also aims to demonstrate the use of these nanosheets as substrates in surface-enhanced Raman spectroscopy. Their adsorption capability and other unique properties could improve the sensitivity, efficiency and affordability of this technique in chemical and biological sensing for applications such as air, water and food safety; and pharmaceutical and cosmetic industries.Read moreRead less
Spinning Nanosheets for Versatile Applications. This project seeks to develop a highly versatile and innovative fibre spinning research platform for fabricating multifunctional hybrid fibres with unprecedented mechanical, electrical and electrochemical properties. The novel fibres to be produced can be assembled into macroscale architectures or be weaved into functional textiles that can feed into relevant technologies and Australian industries such as advanced textiles for wearable energy stora ....Spinning Nanosheets for Versatile Applications. This project seeks to develop a highly versatile and innovative fibre spinning research platform for fabricating multifunctional hybrid fibres with unprecedented mechanical, electrical and electrochemical properties. The novel fibres to be produced can be assembled into macroscale architectures or be weaved into functional textiles that can feed into relevant technologies and Australian industries such as advanced textiles for wearable energy storage and conversion, microelectrodes and sensors, and smart medical/biomedical platforms. More importantly, this project will have far reaching implications across a range of research disciplines, and ultimately sectors critical to Australia’s health, social, and economic future.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180100736
Funder
Australian Research Council
Funding Amount
$362,446.00
Summary
High performing multifunctional silicon nanomaterials for bio-applications. This project aims to develop high-performance, multifunctional silicon nanomaterials, and to understand their physicochemical properties for bio-imaging. A range of high-quality multifunctional silicon-based bio-probes with novel fluorescent and magnetic properties will be developed for enhancing bio-imaging. The outcomes of the project will further strengthen Australia’s leading position in the targeted areas of Advance ....High performing multifunctional silicon nanomaterials for bio-applications. This project aims to develop high-performance, multifunctional silicon nanomaterials, and to understand their physicochemical properties for bio-imaging. A range of high-quality multifunctional silicon-based bio-probes with novel fluorescent and magnetic properties will be developed for enhancing bio-imaging. The outcomes of the project will further strengthen Australia’s leading position in the targeted areas of Advanced Materials and Nanotechnology.Read moreRead less
Highly Efficient Nanomotors for Autonomous Cell Recognition and Isolation. This project aims to develop next-generation self-driven nanomotors capable of long-range motion with highly controlled directionality for cell recognition, transportation and separation in complex biological environments, to allow autonomous and seamless cell sorting with high accuracy. The anticipated goal of this project is to advance the field of nanotechnology and advanced manufacturing with potential to support new ....Highly Efficient Nanomotors for Autonomous Cell Recognition and Isolation. This project aims to develop next-generation self-driven nanomotors capable of long-range motion with highly controlled directionality for cell recognition, transportation and separation in complex biological environments, to allow autonomous and seamless cell sorting with high accuracy. The anticipated goal of this project is to advance the field of nanotechnology and advanced manufacturing with potential to support new applications and to value-add Australia’s advanced manufacturing industry, presenting new opportunities for Australian MedTech industries with innovative, disruptive technologies to address its unique needs and to claim Australia’s position within the competitive global market.Read moreRead less
Development of Novel Functionalised Two-dimensional Nanomaterials. This project aims to develop a series of novel 2D nanomaterials and their nanocomposites that have applications ranging from energy storage via a functional separator for batteries to thermal management devices. Developing novel functional 2D nanomaterials is important for several applications including energy storage, composite materials, and thermal management, as well as advancing knowledge in the control design of 2D nanomate ....Development of Novel Functionalised Two-dimensional Nanomaterials. This project aims to develop a series of novel 2D nanomaterials and their nanocomposites that have applications ranging from energy storage via a functional separator for batteries to thermal management devices. Developing novel functional 2D nanomaterials is important for several applications including energy storage, composite materials, and thermal management, as well as advancing knowledge in the control design of 2D nanomaterials and to promote the development of sustainable energy storage and thermal management technologies. The benefits to Australia, will be in addressing energy and environmental concerns by developing new clean and environmentally friendly energy devices and boosting national economic growth.Read moreRead less
Two-dimensional transition metal nitrides for energy applications. This project aims to develop novel nanomaterials for sustainable energy applications such as blue energy generation and energy storage. The focus is to explore novel 2D transition metal nitride nanomaterials and their advanced heterostructures with large specific surface area, high electrical conductivity and chemical stability. The expected outcomes include development of high-performance devices such as osmotic energy harvestin ....Two-dimensional transition metal nitrides for energy applications. This project aims to develop novel nanomaterials for sustainable energy applications such as blue energy generation and energy storage. The focus is to explore novel 2D transition metal nitride nanomaterials and their advanced heterostructures with large specific surface area, high electrical conductivity and chemical stability. The expected outcomes include development of high-performance devices such as osmotic energy harvesting devices for blue energy generation and micro-supercapacitors for energy storage. This should promote the growth of sectors in advanced materials, sustainable energy generation, smart energy storage and manufacturing, bringing efficient energy generation and storage system benefits to the Australia and the world.Read moreRead less