Engineering improved technology for nanoparticle-based adjuvant manufacture. Over the next decade nanotechnology will redefine vaccines for animal and human health. Nanoparticle adjuvants will boost engineered vaccines that use minimal antigens such as recombinant proteins and synthetic peptides. This project aims to develop a platform technology for making and controlling the properties of inulin nanoparticles by optimising the engineering and manufacturing aspects of inulin nanoparticles to fu ....Engineering improved technology for nanoparticle-based adjuvant manufacture. Over the next decade nanotechnology will redefine vaccines for animal and human health. Nanoparticle adjuvants will boost engineered vaccines that use minimal antigens such as recombinant proteins and synthetic peptides. This project aims to develop a platform technology for making and controlling the properties of inulin nanoparticles by optimising the engineering and manufacturing aspects of inulin nanoparticles to fundamentally understand the relationship between physical-chemical properties and efficacy. Completion of this project aims to produce potent nanoparticle-based adjuvants underpinned by novel manufacturing technology, to ultimately facilitate the development of more effective and protective vaccines for animals and humans.Read moreRead less
Radio-magnetic nanoparticles as bimodal positron emission tomography/magnetic resonance imaging contrast agents for dendritic cell tracking. Biomedical imaging is limited by a lack of commercial dual-mode contrast agents, which may be simultaneously used for magnetic resonance (MR) and positron emission tomography (PET) imaging. This project will develop a nanotechnology-based biocompatible dual-mode contrast agent for simultaneous PET and MR imaging, reducing associated side effects.
Improving battery safety with boron nitride nanotube separators. This project aims to improve the safety of lithium ion batteries by developing high –temperature, stable separators. The use of batteries in a hot Australian summer is a major safety issue for our society. This project will develop a new and safe battery technology with the help of boron nitride nanotubes to effectively reduce the risk of thermal runaway of battery cells. The expected outcomes will have a global impact on the safet ....Improving battery safety with boron nitride nanotube separators. This project aims to improve the safety of lithium ion batteries by developing high –temperature, stable separators. The use of batteries in a hot Australian summer is a major safety issue for our society. This project will develop a new and safe battery technology with the help of boron nitride nanotubes to effectively reduce the risk of thermal runaway of battery cells. The expected outcomes will have a global impact on the safety of the current battery technology and the innovative application of boron nitride nanotubes in battery technology. It will position industry on the cutting edge of battery technology required for energy storage development in Australia.Read moreRead less
Next generation hybrid nanomaterials: bispecific antibody-targeted polymers. This project aims to develop and optimise a novel platform technology that will assist in the development of hybrid materials consisting of nanomaterials and biomolecules, which form the basis of many commercial diagnostic devices. A novel antibody, MIL38, will provide the test bed for the technology, which will aim to deliver a platform that is stable under physiological conditions and that enables facile conjugation o ....Next generation hybrid nanomaterials: bispecific antibody-targeted polymers. This project aims to develop and optimise a novel platform technology that will assist in the development of hybrid materials consisting of nanomaterials and biomolecules, which form the basis of many commercial diagnostic devices. A novel antibody, MIL38, will provide the test bed for the technology, which will aim to deliver a platform that is stable under physiological conditions and that enables facile conjugation of nanomaterials with antibodies. This project has the potential to rapidly improve the ligation process between synthetic nanomaterials and biologics, leading to more efficient synthesis of targeted diagnostics. This would provide a significant commercial advantage for any nanomaterials developed for the field, and specifically for this project, expedite translation of MIL38.Read moreRead less
Novel Fuel Materials for Radiation-Free Proton-Boron Fusion Power Source. Laser proton-boron fusion reactions are a radiation-free nuclear energy source but are limited by a low reaction rate due to a lack of efficient fuel materials. This project aims to develop new fuel materials by synthesising isotope boron 11 enriched hydrogen borides and hydrogen adsorbed boron nitride nanosheets using our research experience in hydrogen storage and nanomateials synthesis. The expected outcomes include tw ....Novel Fuel Materials for Radiation-Free Proton-Boron Fusion Power Source. Laser proton-boron fusion reactions are a radiation-free nuclear energy source but are limited by a low reaction rate due to a lack of efficient fuel materials. This project aims to develop new fuel materials by synthesising isotope boron 11 enriched hydrogen borides and hydrogen adsorbed boron nitride nanosheets using our research experience in hydrogen storage and nanomateials synthesis. The expected outcomes include two new hydrogen storage nanomaterials, the associated new synthesis technologies, and a clean and safe nuclear power source, which helps to reduce carbon dioxide emissions.Read moreRead less
Next generation material imaging, spectrometry and fabrication techniques. This project aims to solve a common, fundamental problem limiting the performance of mass spectrometers and high resolution electron microscopes: surface modification caused by unintended chemical reactions due to electron impact. The intended project outcomes will advance current understanding of electron restructuring of surfaces and open the door to next-generation material imaging, spectrometry and fabrication techniq ....Next generation material imaging, spectrometry and fabrication techniques. This project aims to solve a common, fundamental problem limiting the performance of mass spectrometers and high resolution electron microscopes: surface modification caused by unintended chemical reactions due to electron impact. The intended project outcomes will advance current understanding of electron restructuring of surfaces and open the door to next-generation material imaging, spectrometry and fabrication techniques. It will develop a superior detector for mass spectrometry and improve the imaging and nanofabrication capabilities of state-of-the-art electron microscopes. Read moreRead less
Printable technologies for high security documents and consumer products. Printable technologies for high security documents and consumer products. This project aims to develop two next-generation printable security feature technologies to protect users from counterfeiting, which costs the world economy billions in lost revenue and undermines the security of citizens. First, it aims to enhance the security of banknotes by developing printable active device patches with energy harvesting flexible ....Printable technologies for high security documents and consumer products. Printable technologies for high security documents and consumer products. This project aims to develop two next-generation printable security feature technologies to protect users from counterfeiting, which costs the world economy billions in lost revenue and undermines the security of citizens. First, it aims to enhance the security of banknotes by developing printable active device patches with energy harvesting flexible polymers as a power source and thin film graphene/polymer nanomaterial as an electrode/energy storage media. Second, it aims to design invisible carbon nanotube inks for optical authentication via near infrared activation. Both technologies are expected to thwart sophisticated counterfeits, particularly those supported by organised crime.Read moreRead less
Novel Nano-Pesticides for Animal Healthcare. This project aims to develop a new nano-pesticide with improved safety and performance. Ticks and buffalo fly cause over $400 million each year in economic losses to the Australian livestock industry and are currently treated with highly toxic synthetic pesticides. Spinosad, a naturally derived pesticide with low environmental impact and low toxicity, will be loaded into silica hollow spheres which will improve adhesion to skin or hair and protect aga ....Novel Nano-Pesticides for Animal Healthcare. This project aims to develop a new nano-pesticide with improved safety and performance. Ticks and buffalo fly cause over $400 million each year in economic losses to the Australian livestock industry and are currently treated with highly toxic synthetic pesticides. Spinosad, a naturally derived pesticide with low environmental impact and low toxicity, will be loaded into silica hollow spheres which will improve adhesion to skin or hair and protect against ultraviolet degradation. The nano-spinosad pesticide is expected to have enhanced efficacy and effective duration in field conditions compared to conventional pesticides, significantly reducing the cost of pest control.Read moreRead less
Forensic platform technologies for roadside and workplace testing based on nanostructured silicon chips. Roadside drug testing has recently been incorporated into government legislation throughout Australia and abroad. The objective of this project is to develop advanced analysis technologies for implementing effective roadside and workplace testing. The availability of these technologies will increase the safety of Australian drivers and workers.
Scalable high-density hydrogen storage by nano-bubbles in layered materials. Stable and low-cost hydrogen storage and transportation are cornerstones of a global hydrogen economy. This project aims to advance a novel hydrogen storage technology based on highly pressurised nano-bubbles in layered materials. The project expects to expand our fundamental knowledge of the interactions between hydrogen and layered materials. Expected outcomes include a hydrogen storage technology that exhibits a rema ....Scalable high-density hydrogen storage by nano-bubbles in layered materials. Stable and low-cost hydrogen storage and transportation are cornerstones of a global hydrogen economy. This project aims to advance a novel hydrogen storage technology based on highly pressurised nano-bubbles in layered materials. The project expects to expand our fundamental knowledge of the interactions between hydrogen and layered materials. Expected outcomes include a hydrogen storage technology that exhibits a remarkable energy density, high stability and low cost. This should provide significant benefits, such as improving the capacity and robustness of low-cost hydrogen storage and transportation, reducing energy costs and making hydrogen energy a more accessible and sustainable clean energy source for Australia.Read moreRead less