Discovering And Targeting Genes Regulating Skeletal Muscle Function, Metabolism, And Adaptations To Exercise Interventions
Funder
National Health and Medical Research Council
Funding Amount
$431,000.00
Summary
Muscle wasting and decreased in mitochondrial function due to ageing or lack of physical activity are associated with reduced quality of life. The overarching aim is to develop a unique research program focusing on targeting specific genes, and to discover novel genes regulating muscle wasting and mitochondrial (dis)function. I anticipate this approach to assist in the development of targeted and personalised prevention and therapy for diseases associated with muscle (dis)function.
A Future Beyond the Wall: Improving Post-release Employment Outcomes for People Leaving Prison. Engaging in meaningful work has been shown to reduce re-offending by ex-prisoners, but few prison releasees internationally or in Australia gain employment, and successful pathways to employment for this group are poorly researched and understood. This study aims to gather and analyse, for the first time, comparative data from Australian jurisdictions and employment agencies on the relationship betwee ....A Future Beyond the Wall: Improving Post-release Employment Outcomes for People Leaving Prison. Engaging in meaningful work has been shown to reduce re-offending by ex-prisoners, but few prison releasees internationally or in Australia gain employment, and successful pathways to employment for this group are poorly researched and understood. This study aims to gather and analyse, for the first time, comparative data from Australian jurisdictions and employment agencies on the relationship between in-prison and post-prison vocational education and employment programs, employment and recidivism. It aims to identify effective elements, strategies, program and policy directions in offender training and employment. This is a unique partnership amongst key academics in the field, peak national bodies, correctional and employment organisations.Read moreRead less
Innovations in Clinical Education for Physiotherapy Students. Australia has workforce shortages and an ageing population. Physiotherapists are key players in promoting and maintaining good health through their leadership in physical activity and rehabilitation to retain Australians in the workforce and to ensure quality of life for our ageing population. There is a national shortage of physiotherapists. Increasing numbers of physiotherapists are being trained, requiring new models of clinical tr ....Innovations in Clinical Education for Physiotherapy Students. Australia has workforce shortages and an ageing population. Physiotherapists are key players in promoting and maintaining good health through their leadership in physical activity and rehabilitation to retain Australians in the workforce and to ensure quality of life for our ageing population. There is a national shortage of physiotherapists. Increasing numbers of physiotherapists are being trained, requiring new models of clinical training as there is no capacity in conventional training to cope with student numbers. This research will develop and evaluate new models of training incorporating standardised patients (actors) and simulators (mannequins) which increase education capacity. Models are transferable to other health professions.Read moreRead less
Improving neuronal cell function with cell permeable copper complexes. Metal-based drugs offer an exciting new approach to treatment of neurodegeneration. However, little is known about how cells metabolise these drugs and this information is critical for further drug development. This project will determine how metal-based drugs are metabolised by neuronal cells and how this may result in therapeutic benefit.
Young Australians' perspectives on religions and non-religious worldviews. This project aims to elicit diverse young people’s understandings about religion and belief to inform debate about how education assists or impedes intercultural understanding as well as enhancing wellbeing and social inclusion. Australian governments have invested in programs to promote respect for religious diversity and to counter violent extremism, yet there is no coherent, evidence-based understanding of young Austra ....Young Australians' perspectives on religions and non-religious worldviews. This project aims to elicit diverse young people’s understandings about religion and belief to inform debate about how education assists or impedes intercultural understanding as well as enhancing wellbeing and social inclusion. Australian governments have invested in programs to promote respect for religious diversity and to counter violent extremism, yet there is no coherent, evidence-based understanding of young Australians’ perspectives on religions and nonreligious worldviews. Knowing more about young people's perspectives and what influences them could facilitate development of appropriate educational responses equipping schools to help young Australians to live productively in their diverse society.Read moreRead less
Australian art exhibitions 1968-2009: a generation of cultural transformation. The years 1968 to 2009 witnessed a transformation in the way Australians saw the art of their country. This project investigates the impact of increased funding (government and private) and new scholarship on the curating of art exhibitions, and traces the reconfiguration of Australia’s art history that took place in exhibitions during this period.
The invisible farmer: Securing Australian farm women's history. The invisible farmer: Securing Australian farm women's history. This project, believed to be the first national study of farm women in Australia, aims to address their historical and contemporary invisibility by creating an online, publicly accessible, multimedia documentary database that maps the role women play/played in Australian agriculture. Chief investigators in the fields of social work, women's history, cultural informatics ....The invisible farmer: Securing Australian farm women's history. The invisible farmer: Securing Australian farm women's history. This project, believed to be the first national study of farm women in Australia, aims to address their historical and contemporary invisibility by creating an online, publicly accessible, multimedia documentary database that maps the role women play/played in Australian agriculture. Chief investigators in the fields of social work, women's history, cultural informatics and archival practice will collaborate with community, government and cultural organisations to create digital tools for research, public access and community engagement. Reframing the narrative of rural Australia is expected to create greater understanding and awareness of the value of inclusion, reveal structures of gender inequality in rural communities, and enable significant outcomes in research, industry and public policy.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100031
Funder
Australian Research Council
Funding Amount
$1,000,000.00
Summary
Expanding our view of the Universe with the Murchison Widefield Array. Expanding our view of the Universe with the Murchison Widefield Array:
This project aims to build a Phase 2 Murchison Widefield Array (MWA) to boost the capabilities of the Phase 1 MWA by an order of magnitude. The Epoch of Reionisation (EoR), when the first stars and galaxies lit up the universe, is the last unstudied phase of cosmic evolution. The MWA is at the frontier of EoR research and all-sky survey astrophysics, is t ....Expanding our view of the Universe with the Murchison Widefield Array. Expanding our view of the Universe with the Murchison Widefield Array:
This project aims to build a Phase 2 Murchison Widefield Array (MWA) to boost the capabilities of the Phase 1 MWA by an order of magnitude. The Epoch of Reionisation (EoR), when the first stars and galaxies lit up the universe, is the last unstudied phase of cosmic evolution. The MWA is at the frontier of EoR research and all-sky survey astrophysics, is the only low frequency precursor for the Square Kilometre Array (SKA), and is the only SKA precursor delivering science quality data. This project to construct a Phase 2 MWA would double the number of antennas in the array, double the maximum baseline length, and boost our all-sky survey and EoR capabilities. Read moreRead less
Ethnographies of housing: exploring the role of housing officers in public housing service provision. This research examines the everyday practice of public housing officers working in the Victorian Office of Housing. It aims to analyse the ways that workers exercise discretion, and the patterns of meanings that they construct, through their interactions with clients, departmental managers and other human service providers. It is the first ethnographic study of front-line work in housing servi ....Ethnographies of housing: exploring the role of housing officers in public housing service provision. This research examines the everyday practice of public housing officers working in the Victorian Office of Housing. It aims to analyse the ways that workers exercise discretion, and the patterns of meanings that they construct, through their interactions with clients, departmental managers and other human service providers. It is the first ethnographic study of front-line work in housing services in Australia and builds on comparable work done in the United Kingdom and America. The knowledge generated will inform innovation in public housing services, housing policy debates and emerging programs designed to integrate housing with other human services.Read moreRead less
Adaptive Evolution of BRCA1 in Ancestral Mammals. This project investigates adaptive evolution of BRCA1 in the early radiation of mammals. We will test the hypothesis that the evolution of mammary glands and X chromosome inactivation has resulted in modification of the BRCA1 protein sequence as it aquired new roles in these processes. We will also investigate the importance of these changes inducing compensatory changes in other parts of the protein.