Generation Of Protective Immunity Against Severe Influenza Disease In Indigenous Australians
Funder
National Health and Medical Research Council
Funding Amount
$1,630,970.00
Summary
Hospitalisation and death rates from influenza are high in the Indigenous population, especially when a new virus emerges. There is an urgent need for a vaccine that protects against all influenza strains. T cells recognising conserved viral regions elicit such protection. As T cells are restricted by proteins called HLAs, which vary across ethnicities, we will define T cell regions for HLAs prominent in Indigenous Australians and define how to generate protective immunity against influenza.
Call Out and Listen In: A New Way to Detect and Control Invasive Species. This project aims to use novel acoustic techniques to detect and capture invasive frog species to protect native species. Invasive frogs are an under-appreciated but serious ecological problem worldwide, because they are voracious predators and are often toxic to native species. Male frogs call to attract mates, and answer calls they hear. Using new acoustic technologies, these behaviours can be exploited to detect species ....Call Out and Listen In: A New Way to Detect and Control Invasive Species. This project aims to use novel acoustic techniques to detect and capture invasive frog species to protect native species. Invasive frogs are an under-appreciated but serious ecological problem worldwide, because they are voracious predators and are often toxic to native species. Male frogs call to attract mates, and answer calls they hear. Using new acoustic technologies, these behaviours can be exploited to detect species and attract gravid females for removal. This project aims to combine an early warning system (electronic listening) and trap (calling and catching), which can be customised to any invasive frog, and use it to detect and remove cane toads, especially in low density populations.Read moreRead less