Testing a new model for addressing covert racism faced by Indigenous youth . Racism is associated with poor mental health among Indigenous youth (14-25 years). Previous research has examined overt forms of racism but overlooked subtle and covert forms. This project is designed to provide crucial new knowledge on the forms, impacts, and interpersonal context of covert racism among Indigenous youth. We will adapt, to an Indigenous youth context, an international model of microaggressions (brief, d ....Testing a new model for addressing covert racism faced by Indigenous youth . Racism is associated with poor mental health among Indigenous youth (14-25 years). Previous research has examined overt forms of racism but overlooked subtle and covert forms. This project is designed to provide crucial new knowledge on the forms, impacts, and interpersonal context of covert racism among Indigenous youth. We will adapt, to an Indigenous youth context, an international model of microaggressions (brief, daily acts of covert racism) which focuses on the impacts of racism on targets and the roles of non-Indigenous peoples in either sustaining or ameliorating racism. Expected outcomes will be a new model of covert racism to inform future racism research and interventions in Australia and among other First Nations peoples. Read moreRead less
Investigating The Cellular Response To Iron-Depletion: The Trilogy Of ASK1, Thioredoxin And Ribonucleotide Reductase
Funder
National Health and Medical Research Council
Funding Amount
$552,572.00
Summary
Iron is crucial for many essential biological processes. Recently, we demonstrated that iron-depletion can affects important signalling pathways (e.g., JNK and p38) that play important roles in growth arrest and apoptosis. This study is designed to investigate the cellular and molecular effects of iron depletion which currently remains unclear. The research is crucial for understanding: (1) the effects of iron deficiency and (2) for understanding the effects of iron chelators that are used for t ....Iron is crucial for many essential biological processes. Recently, we demonstrated that iron-depletion can affects important signalling pathways (e.g., JNK and p38) that play important roles in growth arrest and apoptosis. This study is designed to investigate the cellular and molecular effects of iron depletion which currently remains unclear. The research is crucial for understanding: (1) the effects of iron deficiency and (2) for understanding the effects of iron chelators that are used for treating various diseases.Read moreRead less
Testing for scale up: An Indigenous social and emotional learning program . This project takes key learnings from prior research that conceptualised, set up, and tested a social and emotional learning program, Skills for Life (SFL), with Aboriginal and Torres Strait Islander students in grades 7-9 in remote Northern Territory and Queensland schools. It aims to: establish the process and necessary conditions for scaling up SFL to diverse remote schools with Aboriginal and Torres Strait Islander s ....Testing for scale up: An Indigenous social and emotional learning program . This project takes key learnings from prior research that conceptualised, set up, and tested a social and emotional learning program, Skills for Life (SFL), with Aboriginal and Torres Strait Islander students in grades 7-9 in remote Northern Territory and Queensland schools. It aims to: establish the process and necessary conditions for scaling up SFL to diverse remote schools with Aboriginal and Torres Strait Islander students across Australia's top end. Further evidence for the program’s effectiveness will also be built by measuring students’ resilience, help seeking, and psychological distress; and teachers’ cultural awareness; quality of teacher-student relationships, and perceptions of students’ emotional and behavioural difficulties. Read moreRead less
Is transport of miRNAs essential for plant development? This project will provide knowledge of how a new class of biologically active molecule (micro RNA) regulates expression of genes at sites in the plant that are critical for growth and development. MicroRNAs are believed to influence the size and shape of plants, how rapidly they grow and how well they produce and fill seeds. These molecules are part of a group of bioactive signals that move throughout the plant, functioning like hormones bu ....Is transport of miRNAs essential for plant development? This project will provide knowledge of how a new class of biologically active molecule (micro RNA) regulates expression of genes at sites in the plant that are critical for growth and development. MicroRNAs are believed to influence the size and shape of plants, how rapidly they grow and how well they produce and fill seeds. These molecules are part of a group of bioactive signals that move throughout the plant, functioning like hormones but directly influencing how well critical genes work. Their exploitation holds great promise for manipulating plant performance and enhancing crop yields. Read moreRead less
Healing Country: integrating knowledge systems to meet climate challenges. Aboriginal and Torres Strait Islander communities are currently experiencing severe environmental challenges related to a changing climate. Led by Aboriginal communities, this project aims to integrate traditional knowledges and environmental and health data to create community story-data maps. These interactive, online maps will be a unique and powerful blend of information, providing a rich evidence base, decision-suppo ....Healing Country: integrating knowledge systems to meet climate challenges. Aboriginal and Torres Strait Islander communities are currently experiencing severe environmental challenges related to a changing climate. Led by Aboriginal communities, this project aims to integrate traditional knowledges and environmental and health data to create community story-data maps. These interactive, online maps will be a unique and powerful blend of information, providing a rich evidence base, decision-support and communication tool to inform the co-design of local climate change mitigation, adaptation and resilience plans. The project aims to give agency to Aboriginal communities in leading a systems change process to reduce environmental risks and strengthen health and wellbeing.Read moreRead less
Assessing supportive care needs of Indigenous cancer survivors' caregivers. This project aims to gather data about the needs of partners and caregivers of Aboriginal and Torres Strait Islander cancer survivors. The project will undertake a comprehensive exploration of the experiences of caregivers and develop a psychometrically tested tool to assist in identifying unmet needs. The project expects to provide new knowledge about the needs of this population and a validated tool to better assess th ....Assessing supportive care needs of Indigenous cancer survivors' caregivers. This project aims to gather data about the needs of partners and caregivers of Aboriginal and Torres Strait Islander cancer survivors. The project will undertake a comprehensive exploration of the experiences of caregivers and develop a psychometrically tested tool to assist in identifying unmet needs. The project expects to provide new knowledge about the needs of this population and a validated tool to better assess these needs. The project will result in improvements in the assessment of unmet supportive care needs in caregivers of Indigenous cancer survivors, leading to more timely interventions, and a better quality of life for patients and caregivers.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160100216
Funder
Australian Research Council
Funding Amount
$345,000.00
Summary
Emotions, language and culture in Arnhem Land (Katherine region). This project aims to increase our understanding of emotional language and cultural practices about emotions among Indigenous Australian groups. Emotion is a fundamental human experience, yet different languages provide very different ways of talking about it. What are the consequences of this? Are these differences culturally constrained? Might differences in the grammar of a language influence the way its speakers express emotion ....Emotions, language and culture in Arnhem Land (Katherine region). This project aims to increase our understanding of emotional language and cultural practices about emotions among Indigenous Australian groups. Emotion is a fundamental human experience, yet different languages provide very different ways of talking about it. What are the consequences of this? Are these differences culturally constrained? Might differences in the grammar of a language influence the way its speakers express emotions, or even the way they experience emotions? This project seeks to describe and compare the way emotions are expressed in five Aboriginal languages of Arnhem Land. Four of these languages are endangered and the project will also provide the urgent documentation needed to preserve them.Read moreRead less
Genome Approaches to Investigate Metabolic Coordination in Plant Cells. Metabolism of C and N in legume nodules requires interaction between the symbiotic bacteria and plant organelles, particularly metabolism in plastids and mitochondria. Fixed N is assimilated through the de novo synthesis of purines in both plastids and mitochondria. However, each of the nine pathway enzymes is encoded by a single gene, indicating each protein is targeted to both organelles. Purine metabolism will provide ....Genome Approaches to Investigate Metabolic Coordination in Plant Cells. Metabolism of C and N in legume nodules requires interaction between the symbiotic bacteria and plant organelles, particularly metabolism in plastids and mitochondria. Fixed N is assimilated through the de novo synthesis of purines in both plastids and mitochondria. However, each of the nine pathway enzymes is encoded by a single gene, indicating each protein is targeted to both organelles. Purine metabolism will provide a model to assess the more general occurrence of dual-targeted proteins in plants. The aim is to identify and eventually exploit the signalling mechanism(s) that mediate communication between plastids and mitochondria.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100125
Funder
Australian Research Council
Funding Amount
$330,000.00
Summary
Oxidative stress bioanalytical facility. The primary national benefit of this application is that it will provide a currently unavailable, state-of-the-art facility for Australian scientists to define precisely how changes in cellular redox state contribute to biological processes relevant to health and diseases. The facility will uniquely complement, and in many cases integrate with existing facilities in this area of research in Australia. It will act as a platform for major national and inter ....Oxidative stress bioanalytical facility. The primary national benefit of this application is that it will provide a currently unavailable, state-of-the-art facility for Australian scientists to define precisely how changes in cellular redox state contribute to biological processes relevant to health and diseases. The facility will uniquely complement, and in many cases integrate with existing facilities in this area of research in Australia. It will act as a platform for major national and international research collaborations, develop cutting-edge technology and unique local skills, and contribute to Australia maintaining a leading position in redox-related research in biology and medicine. In doing so, the facility will increase the likelihood of gaining future, value-adding funding.Read moreRead less