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We aim to find the right treatment for children and adults with inflammatory arthritis to give the best path to symptom relief with least risk of side effects. We will build on our national data-base and biospecimens bank (A3BC-ARAD) to collect a broad range of patient-reported, biological, environmental and health information to unlock the answers using big-data analysis. We will build a resource and workforce to continue to look for cures to deliver the best outcomes for patients and society.
NHMRC Centre Of Research Excellence For Better Outcomes In Coronary Artery Disease
Funder
National Health and Medical Research Council
Funding Amount
$2,500,000.00
Summary
One Australian suffers a heart attack every 10 min, many without any prior warning. What contributes to atherosclerosis beyond traditional risk factors, and how to manage patients that suffer a heart attack despite no risk factors is not well known. This CRE will establish new biomarkers and clinical pathways for detection of subclinical atherosclerosis as well as secondary prevention strategies whilst fostering the cardiovascular research leaders of the future.
Centre Of Research Excellence In Cardiovascular Outcomes Improvement
Funder
National Health and Medical Research Council
Funding Amount
$2,500,000.00
Summary
Quality, safety and the effectiveness of providing prevention and treatments to those with cardiovascular disease is the focus of research of the CRE in Cardiovascular Outcomes Improvement. Utilizing data derived from clinical registries and large patient databases of patients receiving various treatments for heart problems, we will investigate what factors are important in delivering cost-effective favorable outcomes. The centre will train future leaders in cardiovascular research focusing on
Australasian Cerebral Palsy Clinical Trials Network (AusCP-CTN): Optimising Interventions And Effective Services For Children With Cerebral Palsy
Funder
National Health and Medical Research Council
Funding Amount
$2,499,287.00
Summary
Cerebral Palsy (CP) is common and disability can be progressive so the heathcare burden is immense (0.14% GDP). Our Clinical trials network will improve early detection and develop new interventions to improve physical, cognitive and health outcomes for children with CP and their families. Recruitment from the national CP Register will address clinically important questions and test implementation of effective treatments. New Clinical Practice Guidelines will ensure translation internationally.
Dental Health Services Research For Improved Oral Health Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$2,641,484.00
Summary
This research will generate new knowledge to improve health outcomes by investigating expenditure and financing of dental care, dental practice performance, and the impact of dental services on oral health outcomes. This is needed for health policy to deliver dental care that promotes good oral health, to identify characteristics of the dental delivery system that deliver productive outputs with good outcomes, and testing oral health outcomes in relation to the type of dental care received.
Australian Resuscitation Outcomes Consortium [AUS-ROC] CRE
Funder
National Health and Medical Research Council
Funding Amount
$2,668,571.00
Summary
The Australian Resuscitation Outcomes Consortium (Aus-ROC) will be modelled on the highly successful North American Resuscitation Outcomes Consortium. The mission of Aus-ROC will be to conduct clinical trials and observational studies into the emergency management of out-of-hospital cardiopulmonary arrest. Building on our existing collaborative partnerships, our goal is to improve patient outcomes and build the research capacity in prehospital emergency care.
Centre For Research Excellence In Developmental And Epileptic Encephalopathies
Funder
National Health and Medical Research Council
Funding Amount
$2,500,000.00
Summary
We will study the clinical, genetic and psychological aspects of patients with the most severe group of epilepsies, the Developmental and Epileptic Encephalopathies (DEEs). We will define the clinical spectrum of each genetic DEE, improve health outcomes through understanding the natural history of these diseases, build an integrated model of care, produce family resources and assess health economic impacts. This program will ensure Australia is poised for emerging Precision Medicine trials.
The Victorian Centre For Applied Biostatistics (VCAB): Building Core Methodological Capacity For Population Health
Funder
National Health and Medical Research Council
Funding Amount
$2,497,184.00
Summary
Biostatistics is the scientific discipline that focusses on the methods used to design and analyse research studies on human health. Doctors and other researchers conduct increasingly complex studies to identify best approaches for the prevention and treatment of disease, and these studies must be underpinned by sound biostatistical methods. This Centre will develop a critical mass of expertise in this under-resourced area around a program of methodological research, translation and training.
The Centre for Research Excellence in Discovering Indigenous Strategies to improve Cancer Outcomes Via Engagement, Research Translation and Training (DISCOVER-TT) aims to reduce the marked disparities in diagnosis, treatment and survival for Indigenous Australians with cancer. DISCOVER-TT’s co-ordinated, collaborative, Indigenous-led research program will feature extensive stakeholder engagement to ensure its work is relevant and applicable, and will enhance research capacity by developing early ....The Centre for Research Excellence in Discovering Indigenous Strategies to improve Cancer Outcomes Via Engagement, Research Translation and Training (DISCOVER-TT) aims to reduce the marked disparities in diagnosis, treatment and survival for Indigenous Australians with cancer. DISCOVER-TT’s co-ordinated, collaborative, Indigenous-led research program will feature extensive stakeholder engagement to ensure its work is relevant and applicable, and will enhance research capacity by developing early-career researchers.Read moreRead less
Improving The Lives Of Young People With Type 1 Diabetes Using State-of-the-Art Therapies
Funder
National Health and Medical Research Council
Funding Amount
$2,599,598.00
Summary
T1D profoundly affects the lives of an increasing number of young people and their families. H The proposed centre acknowledges these challenges and recognises the urgent need for a comprehensive and holistic approach involving a broad range of expertise, methodologies and collaboration. The centre will utilize clinical expertise of the CI’s, generating new knowledge for the successful development and use of technology in closed loop and semi-closed systems in young people with T1D.