Discovery And Development Of Better Pain Treatments
Funder
National Health and Medical Research Council
Funding Amount
$9,613,850.00
Summary
Many forms of pain remain poorly treated, leading to significant quality of life and economic losses. This Program grant will discover and characterise new peptides from cone snails and spiders that modulate specific channels in nerves that are critical to the transmission of pain signals to the brain. Using advanced chemical and structural approaches, promising leads will be optimised for potency and stability and evaluated in disease and pathway-specific models of pain to establish their clini ....Many forms of pain remain poorly treated, leading to significant quality of life and economic losses. This Program grant will discover and characterise new peptides from cone snails and spiders that modulate specific channels in nerves that are critical to the transmission of pain signals to the brain. Using advanced chemical and structural approaches, promising leads will be optimised for potency and stability and evaluated in disease and pathway-specific models of pain to establish their clinical potential.Read moreRead less
Taking Time: Work-family time pressure, time quality and healthy activities. Australian families report very high time stress. This project explores links between parental time pressure, health and wellbeing, innovatively capturing individual, family and social perspectives. Using new measures, it analyses time diary data from ten countries to discover how amount, composition and gender share of work-family time affect parents' time quality and healthy activities across different societal contex ....Taking Time: Work-family time pressure, time quality and healthy activities. Australian families report very high time stress. This project explores links between parental time pressure, health and wellbeing, innovatively capturing individual, family and social perspectives. Using new measures, it analyses time diary data from ten countries to discover how amount, composition and gender share of work-family time affect parents' time quality and healthy activities across different societal contexts. It also examines whether there are differences in outcomes by socio-economic status and family structure, in Australia and cross-nationally. The results are expected to inform policy, to promote health and wellbeing, and to encourage sustainable employment-childcare practices.Read moreRead less
Impact of parents' employment on children's well-being: The influence of employment quality, time and activities with children, and parenting practices. Most Australian children now grow-up in families where both their mother and their father are employed. Using a new national dataset, this research examines how parents' working conditions are related to children's well-being. It is proposed that parents' availability, resources, and family functioning mediate between parental employment and chi ....Impact of parents' employment on children's well-being: The influence of employment quality, time and activities with children, and parenting practices. Most Australian children now grow-up in families where both their mother and their father are employed. Using a new national dataset, this research examines how parents' working conditions are related to children's well-being. It is proposed that parents' availability, resources, and family functioning mediate between parental employment and child outcomes. The Growing-Up in Australia study (available in 2005) surveys 10,000 children, combining measures of child well-being, existing validated measures of work conditions and family functioning, with a new child-focused diary that measures time and activities undertaken with children. New knowledge generated will inform future policy development.Read moreRead less
Critical perspectives on serodiscordance in family life. This project aims to produce the first empirical picture of Australian families affected by HIV, hepatitis C or hepatitis B, to shed light on how families manage adversity in diverse households and community contexts. The project plans to conduct qualitative research with individuals, families and other stakeholders to reveal the interplay between diversity in family forms and understandings and experiences of serodiscordance, or mixed inf ....Critical perspectives on serodiscordance in family life. This project aims to produce the first empirical picture of Australian families affected by HIV, hepatitis C or hepatitis B, to shed light on how families manage adversity in diverse households and community contexts. The project plans to conduct qualitative research with individuals, families and other stakeholders to reveal the interplay between diversity in family forms and understandings and experiences of serodiscordance, or mixed infection status. In developing a critical theory of serodiscordance that departs from the biomedical emphasis on ‘risk management’, novel insights are anticipated on accommodating difference and disruption, managing secrets and stigma, and responsibilising care and treatment within families. The project also anticipates the generation of new and important knowledge regarding the contributions of families to community wellbeing.Read moreRead less
Experiences of addiction, treatment and recovery: An online resource for members of the public, health professionals and policymakers. Alcohol and other drug addiction is a major health and social issue in Australia. Treatment success rates are modest and little is known about how people experience and manage addiction and the stigma that accompanies it. This project will generate new knowledge on alcohol and other drug addiction by applying a proven qualitative methodology to these issues for t ....Experiences of addiction, treatment and recovery: An online resource for members of the public, health professionals and policymakers. Alcohol and other drug addiction is a major health and social issue in Australia. Treatment success rates are modest and little is known about how people experience and manage addiction and the stigma that accompanies it. This project will generate new knowledge on alcohol and other drug addiction by applying a proven qualitative methodology to these issues for the first time. It will produce an effective, innovative online resource for affected Australians, their family and friends, and the wider Australian community including health professionals and policymakers.Read moreRead less
Violence Against Women - A Media Intervention. This project aims to by explore the link between the internal operations of news media organisations, news media outputs and their impact on community attitudes to violence against women. Current literature indicates that the paucity and tone of news reporting of violence against women perpetuates harmful attitudes towards women. International and Australian research has consistently identified community attitudes as a key causal factor in violence ....Violence Against Women - A Media Intervention. This project aims to by explore the link between the internal operations of news media organisations, news media outputs and their impact on community attitudes to violence against women. Current literature indicates that the paucity and tone of news reporting of violence against women perpetuates harmful attitudes towards women. International and Australian research has consistently identified community attitudes as a key causal factor in violence against women. However, there is a lack of research into the impact of newsroom operations, including gender politics, on news media outputs, and the impact of those outputs on community attitudes. The proposed research and intervention project seek to address this shortfall.Read moreRead less
Cultural competence in supporting Cambodians recovering from conflict. This project will (1) reduce the impact of conflict for the next generation, a key to a healthy start to life and ageing well (2) guide interventions in regional settings (3) inform guidelines for refugee programs in Australia (4) highlight culture as redressing weakened traditional support structures of survivors of war in Australia and the region, supporting the Government's welfare reform and participation agendas (5) equi ....Cultural competence in supporting Cambodians recovering from conflict. This project will (1) reduce the impact of conflict for the next generation, a key to a healthy start to life and ageing well (2) guide interventions in regional settings (3) inform guidelines for refugee programs in Australia (4) highlight culture as redressing weakened traditional support structures of survivors of war in Australia and the region, supporting the Government's welfare reform and participation agendas (5) equip Australia to understand insecurities of globalisation and what survivors of war can be driven to do - unless their culture is used as an asset rather than a source of terror (6) enhance Australia's capacity to engage with its cultural environment (7) enhance capacity for AusAID to interpret itself to the rest of the world.Read moreRead less
Meals on Wheels: building towards a new social experiment for our times. This project contributes directly to the National Research Priority, promoting and maintaining good health: ageing well, ageing productively, through developing evidence-based knowledge on which to build future volunteer business models. With the rapid ageing of the Australian population, it is imperative that volunteer-based organisations, such as Meals on Wheels, innovate to continue to deliver essential community service ....Meals on Wheels: building towards a new social experiment for our times. This project contributes directly to the National Research Priority, promoting and maintaining good health: ageing well, ageing productively, through developing evidence-based knowledge on which to build future volunteer business models. With the rapid ageing of the Australian population, it is imperative that volunteer-based organisations, such as Meals on Wheels, innovate to continue to deliver essential community services in a sustainable and cost-effective way. Meals on Wheels is integral within community care for frail, older people and those with disabilities, keeping people in their own homes and out of institutional care. Using national and international examples, the research has the potential to be adopted by the broad community services sector in Australia.Read moreRead less
Special Research Initiatives - Grant ID: SR0354852
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Sustainable Regions for a Competitive Australia. How can metropolitan, rural and remote regions balance economic and job growth, with environmental and social sustainability? This Initiative establishes a Network of researchers to work collaboratively on questions of environmental best practice, community development, regional governance, labour markets, economic development and technology transfer. The Network's vision is to find ways to use existing and future research to help make Australia ....Sustainable Regions for a Competitive Australia. How can metropolitan, rural and remote regions balance economic and job growth, with environmental and social sustainability? This Initiative establishes a Network of researchers to work collaboratively on questions of environmental best practice, community development, regional governance, labour markets, economic development and technology transfer. The Network's vision is to find ways to use existing and future research to help make Australia's regions more competitive on world markets and more environmentally sustainable, and to help build stronger regional communities. The Network cuts across traditional discipline boundaries to find integrated solutions to the real problems confronting Australian regions.Read moreRead less
Belonging and sexual citizenship among gender and sexual minority youth. In the context of well-documented threats to the mental health and well-being of minority young people, this project will examine the experiences of two different generations of gender and sexual minority youth growing up in Australia, and the sources of support they have found most useful. Innovative contextual analysis will involve documentary and archival research alongside individual and group interviews. Through a focu ....Belonging and sexual citizenship among gender and sexual minority youth. In the context of well-documented threats to the mental health and well-being of minority young people, this project will examine the experiences of two different generations of gender and sexual minority youth growing up in Australia, and the sources of support they have found most useful. Innovative contextual analysis will involve documentary and archival research alongside individual and group interviews. Through a focus on the promotion of well-being and participatory citizenship in a rapidly changing social world, the findings aim to contribute new theory concerning transitions from youth to adulthood, improved methodology for the study of marginal and sometimes hard-to-reach populations, and better quality policy and practice.Read moreRead less