Structural And Functional Analysis Of A Cancer-linked Co-regulator Complex
Funder
National Health and Medical Research Council
Funding Amount
$729,571.00
Summary
We seek to understand the mechanisms by which genes are switched on and off throughout our lifetime. A number of multi-component protein machines are involved in this process but their make-up and mechanism of action is not understood. We will investigate the structure and function of one of these machines that has been strongly linked to cancer.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100074
Funder
Australian Research Council
Funding Amount
$580,000.00
Summary
Data Co-operative Platform for Social Impact and Wellbeing. The Data Cooperative (Co-Op) Platform for Social Impact and Wellbeing aims to make data-driven research and decision-making in the social sciences more effective and efficient by developing infrastructure to support data integration and harmonisation of diverse data resources. Social research relies on a vast array of data types and sources, both open and confidential, making data analysis complex and time-consuming. This project will d ....Data Co-operative Platform for Social Impact and Wellbeing. The Data Cooperative (Co-Op) Platform for Social Impact and Wellbeing aims to make data-driven research and decision-making in the social sciences more effective and efficient by developing infrastructure to support data integration and harmonisation of diverse data resources. Social research relies on a vast array of data types and sources, both open and confidential, making data analysis complex and time-consuming. This project will drive innovation across a range of critical social issues that require integrated data for research and social innovation including healthcare, better outcomes for disadvantaged and vulnerable groups, resilient urban, rural and regional communities, and increasing our capacity to respond to climate change. Read moreRead less
Wild Man from Borneo: species, race, representation. This project addresses the representation of species boundaries in Western accounts of the orangutan in the 19th and 20th centuries. Darwinian theory raised the possibility that animals could ?evolve?. Orangutans seemed ?closest? to humans and therefore raised key questions about the border between humans and animals. These questions were addressed in a vast range of scientific, popular, imaginative and juvenile literature. Even when ecolo ....Wild Man from Borneo: species, race, representation. This project addresses the representation of species boundaries in Western accounts of the orangutan in the 19th and 20th centuries. Darwinian theory raised the possibility that animals could ?evolve?. Orangutans seemed ?closest? to humans and therefore raised key questions about the border between humans and animals. These questions were addressed in a vast range of scientific, popular, imaginative and juvenile literature. Even when ecological models of the environment shifted attention from evolutionary potential to ecological role, orangutans retained a special status as ?sentinel? species. This project will produce a monograph examining the construction, maintenance and erosion of ideas of species boundaries.Read moreRead less
Mobile Indonesians: social differentiation and digital literacies in the twenty first century. This is the first dedicated study of the social implications of mobile telephony's recent and rapid popularisation throughout the country. This project will study metropolitan, urban and rural users to understand how mobile phones create the new and unexpected social networks which will shape tomorrow's Indonesians.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE140100148
Funder
Australian Research Council
Funding Amount
$460,000.00
Summary
TrISMA - Tracking Infrastructure for Social Media Analysis. Tracking infrastructure for social media analysis: The tracking infrastructure for social media analysis (TrISMA) project establishes state-of-the-art technical and organisational infrastructure for the tracking of public communication by Australian users of social media, at large scale, in real time, and for the long term, addressing a significant gap in national research infrastructure. Social media are increasingly embedded in the Au ....TrISMA - Tracking Infrastructure for Social Media Analysis. Tracking infrastructure for social media analysis: The tracking infrastructure for social media analysis (TrISMA) project establishes state-of-the-art technical and organisational infrastructure for the tracking of public communication by Australian users of social media, at large scale, in real time, and for the long term, addressing a significant gap in national research infrastructure. Social media are increasingly embedded in the Australian media ecology, and systematic analyses of how public communication takes place via social media provide rich insights into a range of issues and debates of high importance to our society.Read moreRead less
ARC Research Network in Spatially Integrated Social Science. The ARC Research Network in Spatially Integrated Social Science (SISS) builds Australia's capacity and capability for innovative, collaborative, cross-disciplinary effort to investigate the impacts of change on the behaviour and well-being of people and the fortunes of places. SISS theories and research tools permit the integration of diverse and complex databases, the generation of new synthetic datasets, the incorporation of spatial ....ARC Research Network in Spatially Integrated Social Science. The ARC Research Network in Spatially Integrated Social Science (SISS) builds Australia's capacity and capability for innovative, collaborative, cross-disciplinary effort to investigate the impacts of change on the behaviour and well-being of people and the fortunes of places. SISS theories and research tools permit the integration of diverse and complex databases, the generation of new synthetic datasets, the incorporation of spatial concepts into statistical analysis and modelling, powerful visualisation of information, and the building spatial decision support systems, to provide an improved evidence base and better informed decision-making to address the significant challenges facing Australia's people and its places.Read moreRead less
So what do you do? Graduates in the Creative and Cultural Industries. This project plans to analyse national graduate employment in Australia’s creative and cultural industries, and compare the utility of 'creative' and 'cultural' models for tracking employment outcomes. Although the image of work in the creative and cultural industries is attractive to students and course planners alike, international evidence suggests graduates face very poor employment prospects. The project plans to use a pr ....So what do you do? Graduates in the Creative and Cultural Industries. This project plans to analyse national graduate employment in Australia’s creative and cultural industries, and compare the utility of 'creative' and 'cultural' models for tracking employment outcomes. Although the image of work in the creative and cultural industries is attractive to students and course planners alike, international evidence suggests graduates face very poor employment prospects. The project plans to use a proven model for mapping creative graduates to compare the value of creative degrees for the creative workforce in two nations, Australia and the United Kingdom; and to use sophisticated quantitative analysis of national datasets and interviews to produce a comprehensive study of creative graduate work.Read moreRead less
Memories of utopia: Destroying the past to create the future (300-650 CE). This project aims to examine the evidence for competing utopian ideologies in early Christianity, which was a prelude to the later clash with Islam from the seventh century onward. Evidence from pagan-Jewish-Christian conflicts in Late Antiquity (300-650 CE) shows that violent destruction of the past is not exclusive to fringe religious groups. These past conflicts are relevant for understanding the conflict in the Middle ....Memories of utopia: Destroying the past to create the future (300-650 CE). This project aims to examine the evidence for competing utopian ideologies in early Christianity, which was a prelude to the later clash with Islam from the seventh century onward. Evidence from pagan-Jewish-Christian conflicts in Late Antiquity (300-650 CE) shows that violent destruction of the past is not exclusive to fringe religious groups. These past conflicts are relevant for understanding the conflict in the Middle East, precisely because analysis of the sources shows that, in intra- and inter-religious conflicts in Late Antiquity in this same geographic region, violent destruction of the past was a propensity in mainstream religion.Read moreRead less
Urban Imaginaries/Cultural Landscapes: An Asia-Pacific Transnational and Cross-Cultural Research Collaboration. The aim of the program is to foster research collaboration between the ANU's Humanities Research Centre and Lingnan University's Cultural Research and Development Program by examining public culture, transnational culture, urban landscapes and urban cultural identities in the contemporary Asia-Pacific and Australian context. We will do this by extending ties with researchers from the ....Urban Imaginaries/Cultural Landscapes: An Asia-Pacific Transnational and Cross-Cultural Research Collaboration. The aim of the program is to foster research collaboration between the ANU's Humanities Research Centre and Lingnan University's Cultural Research and Development Program by examining public culture, transnational culture, urban landscapes and urban cultural identities in the contemporary Asia-Pacific and Australian context. We will do this by extending ties with researchers from the region including early career and students and by developing a comparative cross-cultural methodology capable of encompassing specific socio-historical patterns and processes of dynamically changing public cultural formations in contemporary urban centres in the Asia-Pacific, including Australia. Specific outcomes include a book, e-journal and a multi-media exhibition.
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Unsaturation of vapour pressure inside leaves: fundamental, but unknown. This project aims to determine when and to what extent the air inside leaves becomes unsaturated with water vapour. All current interpretation and modelling of leaf gas exchange assumes saturation under all circumstances. Compelling evidence has been obtained that suggests this is not true under moderate air vapour pressure deficits. A novel technique will be employed to assess the water vapour concentration of the air insi ....Unsaturation of vapour pressure inside leaves: fundamental, but unknown. This project aims to determine when and to what extent the air inside leaves becomes unsaturated with water vapour. All current interpretation and modelling of leaf gas exchange assumes saturation under all circumstances. Compelling evidence has been obtained that suggests this is not true under moderate air vapour pressure deficits. A novel technique will be employed to assess the water vapour concentration of the air inside leaves based on stable isotope analysis of carbon dioxide and water vapour exchanged between leaves and air. The project is expected to provide fundamental knowledge about how stomata regulate photosynthesis and water use, with significant implications for modelling vegetation function and for improving the performance of crop plants.Read moreRead less