Glycan-based prebiotic approaches to increase food safety in Australia. Since the launch of the first Australian Animal Sector National Antimicrobial Resistance Plan (2018) several approaches have been suggested to reduce the use antibiotics in agriculture, however no alternatives to antibiotics have been suggested or trialled. In this proposal we aim to develop a novel glycan-based prebiotic strategy to reduce Campylobacter jejuni colonisation in chicken and poultry by disrupting important glyc ....Glycan-based prebiotic approaches to increase food safety in Australia. Since the launch of the first Australian Animal Sector National Antimicrobial Resistance Plan (2018) several approaches have been suggested to reduce the use antibiotics in agriculture, however no alternatives to antibiotics have been suggested or trialled. In this proposal we aim to develop a novel glycan-based prebiotic strategy to reduce Campylobacter jejuni colonisation in chicken and poultry by disrupting important glycan-glycan interactions. Outcomes of this proposal is a cost-effective antibiotic- and vaccine-independent animal feed supplement strategy that will decrease the risk of human food-borne illness and therefore promoting food safety and public health in Australia. Read moreRead less
Australian Laureate Fellowships - Grant ID: FL230100104
Funder
Australian Research Council
Funding Amount
$3,400,000.00
Summary
Bringing Equality Home: A New Gender Agenda. Compared to other countries, Australia has slipped backwards in achieving gender equality and is in danger of falling further behind. This jeopardises opportunities for all Australians and undermines social cohesion and economic progress. This project aims to provide the theoretical and empirical foundations to reverse this trend. The expected outcomes will be a new theory of gender inequality, a new approach that foregrounds the explanatory importanc ....Bringing Equality Home: A New Gender Agenda. Compared to other countries, Australia has slipped backwards in achieving gender equality and is in danger of falling further behind. This jeopardises opportunities for all Australians and undermines social cohesion and economic progress. This project aims to provide the theoretical and empirical foundations to reverse this trend. The expected outcomes will be a new theory of gender inequality, a new approach that foregrounds the explanatory importance of caregiving and domestic work and new insights into the life course stages where gender inequality is most malleable. This will provide significant benefits including the impetus for new research, policy initiatives and capacity to build a more equal, stronger and prosperous Australia.Read moreRead less
How parents manage climate anxiety: coping and hoping for the whole family. This project studies how Australian parents manage climate anxiety for themselves and their families. Using mixed-methods/mixed-media approaches, it examines whether an increase in climate disasters is accelerating the spread of collective anxiety amongst families, how parents manage this anxiety for their children and partners, and if there are associated mental health burdens and gendered inequities in this management. ....How parents manage climate anxiety: coping and hoping for the whole family. This project studies how Australian parents manage climate anxiety for themselves and their families. Using mixed-methods/mixed-media approaches, it examines whether an increase in climate disasters is accelerating the spread of collective anxiety amongst families, how parents manage this anxiety for their children and partners, and if there are associated mental health burdens and gendered inequities in this management. It also looks at climate anxiety management across generations and climate histories, drawing out pessimistic/optimistic narratives about the future to enable action, resilience, and hope. It will produce an evidence base and photo-voice/documentary resources to help parents and support organisations combat climate anxiety.Read moreRead less
Early Career Industry Fellowships - Grant ID: IE230100410
Funder
Australian Research Council
Funding Amount
$452,085.00
Summary
Bridging the gap between rockfall theory and engineering practice. Fragmentation is often observed post rockfall events and it is recognised as a critical aspect of adequate rockfall risk management. Yet, rockfall fragmentation is a complex phenomenon still poorly understood and not properly considered in engineering practice. This project aims at developing a theoretical and stochastic fragmentation framework, based on high-quality and comprehensive experimental data, in collaboration with lead ....Bridging the gap between rockfall theory and engineering practice. Fragmentation is often observed post rockfall events and it is recognised as a critical aspect of adequate rockfall risk management. Yet, rockfall fragmentation is a complex phenomenon still poorly understood and not properly considered in engineering practice. This project aims at developing a theoretical and stochastic fragmentation framework, based on high-quality and comprehensive experimental data, in collaboration with leading international industry partners that provide advanced geotechnical design tools to practitioners around the world. The outcomes of the project will bridge the gap between rockfall theory and engineering practice. It will allow for more cost-effective and safer design of rockfall protection structures.Read moreRead less
A community based social identity approach to loneliness. Loneliness across Australia is a deep concern. Social prescribing is a novel community-based approach to managing loneliness, however it is unclear when and in what circumstances it is effective. This project aims to test a social identity approach to loneliness, incorporating longitudinal, cross-sectional, and experimental methods to understand how best to engage isolated people in group programs. The expected benefits of this project ar ....A community based social identity approach to loneliness. Loneliness across Australia is a deep concern. Social prescribing is a novel community-based approach to managing loneliness, however it is unclear when and in what circumstances it is effective. This project aims to test a social identity approach to loneliness, incorporating longitudinal, cross-sectional, and experimental methods to understand how best to engage isolated people in group programs. The expected benefits of this project are to produce a validated social prescribing model that can be implemented in multiple settings across Australia in order to reduce loneliness, strengthen communities, and guide more appropriate uses of health services.Read moreRead less
Exploring volcanic arcs as factories of critical minerals. Volcanoes at destructive plate boundaries (magmatic arcs) host most global copper deposits, critical for renewable energy and in unprecedented rising demand. This project aims to use high-resolution geochemical zoning of erupted crystals to uncover how magmatic processes lead to copper mineralisation and explosive volcanic eruption in arc volcanoes. The expected outcome is new knowledge on the inner workings of volcanoes and their copper ....Exploring volcanic arcs as factories of critical minerals. Volcanoes at destructive plate boundaries (magmatic arcs) host most global copper deposits, critical for renewable energy and in unprecedented rising demand. This project aims to use high-resolution geochemical zoning of erupted crystals to uncover how magmatic processes lead to copper mineralisation and explosive volcanic eruption in arc volcanoes. The expected outcome is new knowledge on the inner workings of volcanoes and their copper enrichment potential. Anticipated applications are refined exploration targeting for copper and improved volcano hazard assessment. This will benefit the Asia-Pacific region and enhance the capacity of mining companies in the global race to produce metals of the future.Read moreRead less
Mathematical Decision Support to Optimise Hospital Capacity and Utilisation. Hospital planners and executives regularly contend with challenging capacity related decisions. Decisions relating to prioritisation, allocation and sharing of resources have a profound impact on productivity, efficiency and patient outcomes. There is a lack of data-driven or quantitative decision support to make well-informed capacity related decisions of a strategic or tactical nature in a single hospital, or across a ....Mathematical Decision Support to Optimise Hospital Capacity and Utilisation. Hospital planners and executives regularly contend with challenging capacity related decisions. Decisions relating to prioritisation, allocation and sharing of resources have a profound impact on productivity, efficiency and patient outcomes. There is a lack of data-driven or quantitative decision support to make well-informed capacity related decisions of a strategic or tactical nature in a single hospital, or across a regional healthcare system. This project aims to deliver decision support for holistic hospital capacity assessment and planning optimisation. This will yield significant benefits for the health sector, providing a tool to optimise the allocation of resources and provision of infrastructure for regional hospital services.Read moreRead less
Confronting everyday harms: preventing abuse of people with disability. The findings of the Disability Royal Commission necessitate new approaches to prevent violence, abuse, neglect and exploitation. Framed by recognition theory, this project proposes empirical research with young people with cognitive disability, using a new concept of ‘everyday harms’ in their paid relationships. The results will inform early responses to poor quality interactions in disability support. The strategic alliance ....Confronting everyday harms: preventing abuse of people with disability. The findings of the Disability Royal Commission necessitate new approaches to prevent violence, abuse, neglect and exploitation. Framed by recognition theory, this project proposes empirical research with young people with cognitive disability, using a new concept of ‘everyday harms’ in their paid relationships. The results will inform early responses to poor quality interactions in disability support. The strategic alliances with the government, industry and community partners will develop a practice framework to prevent everyday harms and the escalation to abuse, and to promote safety and wellbeing. The research has policy benefits for capacity-building in the sector to act on the rights and voices of people with disability. Read moreRead less
Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The pr ....Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The project will provide fundamental advances in our knowledge of the nutrient transport during pregnancy that is required to produce a healthy baby.Read moreRead less
Deciphering the regulatory principles of metazoan development. This proposal aims to elucidate how regulatory elements in the genome, known as enhancers, determine the identity and function of animal tissues. Currently, it is believed that enhancers cannot be traced across evolutionarily distant animals. The project uses novel concepts, computational and molecular approaches to identify deeply conserved enhancers. It further dissects the mechanism of function by proteomics and high-throughput ge ....Deciphering the regulatory principles of metazoan development. This proposal aims to elucidate how regulatory elements in the genome, known as enhancers, determine the identity and function of animal tissues. Currently, it is believed that enhancers cannot be traced across evolutionarily distant animals. The project uses novel concepts, computational and molecular approaches to identify deeply conserved enhancers. It further dissects the mechanism of function by proteomics and high-throughput genomics. The expected outcomes will overturn our current view on enhancer evolution and reposition our understanding of how enhancers are functionally encoded in the genome. The work is an important contribution to understanding cellular complexity and species evolution with wide-ranging impact in genetics.Read moreRead less