Design of Welded Steel Tubular Connections. Steel tubes are widely used in building, road transportation, defence, recreation, and agriculture industries. The proposed program will develop static design procedures for welded tubular connections to ensure safe and economic structures. The program will also investigate the behaviour of a popular tubular connection utilizing very high strength steel tubes to extend the existing design scope and enhance the utilization of Australian produced innovat ....Design of Welded Steel Tubular Connections. Steel tubes are widely used in building, road transportation, defence, recreation, and agriculture industries. The proposed program will develop static design procedures for welded tubular connections to ensure safe and economic structures. The program will also investigate the behaviour of a popular tubular connection utilizing very high strength steel tubes to extend the existing design scope and enhance the utilization of Australian produced innovative tubular sections. The notch toughness of steel tubes will also be investigated to avoid fracture failure of welded connections under dynamic loading. The program will build strong ongoing collaboration between University of Toronto and Monash University.Read moreRead less
Interaction of Local and Distortional Buckling in Thin-Walled High Strength Steel Sections. Recent research at the University of Sydney has shown that the local and distortional buckling modes in thin-walled high strength steel sections may have adverse interaction. Cold-Formed steel sections of this type are used in residential construction, ceiling systems, partitioning systems in offices and other light gauge applications. The project will develop mathematical models of the interaction beha ....Interaction of Local and Distortional Buckling in Thin-Walled High Strength Steel Sections. Recent research at the University of Sydney has shown that the local and distortional buckling modes in thin-walled high strength steel sections may have adverse interaction. Cold-Formed steel sections of this type are used in residential construction, ceiling systems, partitioning systems in offices and other light gauge applications. The project will develop mathematical models of the interaction behaviour of sections of this type for a wide range of section geometries. A major outcome will be design methods which accurately quantify the interaction behaviour based on the models. Testing will be undertaken to support the theoretical developments and to calibrate the design models.Read moreRead less
Structural behaviour of innovative hollow flange steel members subject to local and lateral distortional buckling effects. This project will investigate the local and lateral distortional buckling behaviour of a new generation of innovative and cost-effective thin and high strength steel hollow flange sections (HFS) being developed using a unique dual weld and roll-forming technology. It will use experiments and advanced numerical modelling to develop fundamental behavioural and design data for ....Structural behaviour of innovative hollow flange steel members subject to local and lateral distortional buckling effects. This project will investigate the local and lateral distortional buckling behaviour of a new generation of innovative and cost-effective thin and high strength steel hollow flange sections (HFS) being developed using a unique dual weld and roll-forming technology. It will use experiments and advanced numerical modelling to develop fundamental behavioural and design data for HFS flexural members. Effects of web corrugations and punched holes will also be investigated. The research will enable innovative applications using HFS in the building industry in Australia and overseas. It will bring significant economic benefits to the industry partner, steel building industry, and Australia.Read moreRead less
Structural Behaviour of Innovative LiteSteel Beams, their Design Improvements and Applications. This project will develop a significant knowledge base, accurate design models and innovative application methods for the new LSB, which will be fully used by the collaborating partner in marketing them in Australia and overseas. Both construction and manufacturing industry sectors will benefit through the increased use of the innovative and lightweight hollow flange sections. Using the new sections a ....Structural Behaviour of Innovative LiteSteel Beams, their Design Improvements and Applications. This project will develop a significant knowledge base, accurate design models and innovative application methods for the new LSB, which will be fully used by the collaborating partner in marketing them in Australia and overseas. Both construction and manufacturing industry sectors will benefit through the increased use of the innovative and lightweight hollow flange sections. Using the new sections and the wealth of design information from this research, Australian engineers can develop cost-effective and safer building systems. Community at large, in particular rural and regional communities will gain through cheaper building systems, additional employment in LSB manufacturing and design, and opportunities locally and overseas.Read moreRead less
Artificial Synthesis Of The Type III Secretion System Translocon. A New Approach To Vaccine Design
Funder
National Health and Medical Research Council
Funding Amount
$668,742.00
Summary
Today hospitals are plagued with bacterial infections that do not respond to antibiotics. The problem exists because although antibiotics are effective at killing bacteria, this paradoxically also helps the drug-resistant bacteria thrive. We will pioneer a completely new approach to vaccine design that allows us to construct a vaccine that protects us from bacterial infection without killing the bacteria. The vaccine should therefore be far less susceptible to drug resistance.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100118
Funder
Australian Research Council
Funding Amount
$600,000.00
Summary
Nuclear magnetic resonance spectroscopy facilities for the Sydney region. The determination of molecular structure is crucial in the chemical and biomolecular sciences, leading to the development of new drugs and other types of molecules and providing an understanding of how molecules interact with each other. The requested equipment will provide the ability for researchers in the Sydney region to advance our knowledge at this fundamental level by expanding the number and types of experiments th ....Nuclear magnetic resonance spectroscopy facilities for the Sydney region. The determination of molecular structure is crucial in the chemical and biomolecular sciences, leading to the development of new drugs and other types of molecules and providing an understanding of how molecules interact with each other. The requested equipment will provide the ability for researchers in the Sydney region to advance our knowledge at this fundamental level by expanding the number and types of experiments that can be performed.Read moreRead less
A reliable physical model of molecular motion in crystals. The scientific benefits would flow, in the first instance, to the large national and international communities of scientists whose research makes use of the results of X-ray diffraction experiments. Applications of the research to amino acids and peptides will benefit investigations into the structure and molecular dynamics of biological systems, including proteins and enzymes. Studies of charge densities in crystals will obtain a standa ....A reliable physical model of molecular motion in crystals. The scientific benefits would flow, in the first instance, to the large national and international communities of scientists whose research makes use of the results of X-ray diffraction experiments. Applications of the research to amino acids and peptides will benefit investigations into the structure and molecular dynamics of biological systems, including proteins and enzymes. Studies of charge densities in crystals will obtain a standard tool for improved modelling of molecular motion, resulting in physically more realistic charge density functions, and hence greater insight into the relationship between properties of crystals and their constituent molecules.Read moreRead less
Reliability and design of 3D printed metal structures. The project will produce a design framework for additively manufactured (3D printed) metal structures. The project will develop open source algorithms for predicting (i) mechanical properties of 3D printed metals for given printing parameters and (ii) internal stresses and distortions arising from the printing process. Underpinned by experiments on structural components and structural reliability analyses, models will be calibrated for the n ....Reliability and design of 3D printed metal structures. The project will produce a design framework for additively manufactured (3D printed) metal structures. The project will develop open source algorithms for predicting (i) mechanical properties of 3D printed metals for given printing parameters and (ii) internal stresses and distortions arising from the printing process. Underpinned by experiments on structural components and structural reliability analyses, models will be calibrated for the nonlinear analysis of 3D printed structures, and a methodology will be set out for designing 3D printed metal structures with acceptably low probability of failure. The project will enable structural engineers to safely and efficiently design 3D printed metal structures and components.Read moreRead less
Developing auxetic composite system for protective engineering applications. This project intends to explore the possibilities of extending the latest developments in auxetic technologies to the protective design of engineering structures. Auxetic materials become thicker perpendicular to the applied force when stretched. Specifically, the project plans to develop a novel auxetic composite system with a focus on protecting civil and defence infrastructure from extreme loads. It is expected that ....Developing auxetic composite system for protective engineering applications. This project intends to explore the possibilities of extending the latest developments in auxetic technologies to the protective design of engineering structures. Auxetic materials become thicker perpendicular to the applied force when stretched. Specifically, the project plans to develop a novel auxetic composite system with a focus on protecting civil and defence infrastructure from extreme loads. It is expected that the system’s superior energy dissipating capability will broaden its application beyond civil infrastructure, such as armoured vehicles, protective sports gear and body armour. The project also plans to develop a multiscale numerical modelling and topological optimisation framework to accelerate the adoption of this advanced composite system.Read moreRead less