Australian Laureate Fellowships - Grant ID: FL140100179
Funder
Australian Research Council
Funding Amount
$2,800,000.00
Summary
Controlling gene expression with synthetic RNA-binding proteins. Controlling gene expression with synthetic RNA-binding proteins. The growth and development of living organisms is largely determined by the genes they contain, but converting the genetic information into biological activity requires intermediary processes involving RNA and proteins that bind to and process RNA. This project aims to understand how the largest class of RNA-binding protein in plants recognise their target RNAs and ai ....Controlling gene expression with synthetic RNA-binding proteins. Controlling gene expression with synthetic RNA-binding proteins. The growth and development of living organisms is largely determined by the genes they contain, but converting the genetic information into biological activity requires intermediary processes involving RNA and proteins that bind to and process RNA. This project aims to understand how the largest class of RNA-binding protein in plants recognise their target RNAs and aims to develop custom-designed proteins for switching genes on or off. This technology will be used to create new hybrid cereal varieties and will also be valuable for applications in human health, such as the correction of genetic mutations.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL200100057
Funder
Australian Research Council
Funding Amount
$3,311,491.00
Summary
Dynamic Proteins for Nutritious Future Crops. This project aims to understand the processes and genes that regulate synthesis and degradation of proteins in wheat and barley plants. This project will develop methodologies and a new field of research for optimising protein stability in crops. Its significance lies in defining new ways to control protein abundance to increase crop performance and quality and increase the value of recombinant proteins for biotech industries. Expected outcomes will ....Dynamic Proteins for Nutritious Future Crops. This project aims to understand the processes and genes that regulate synthesis and degradation of proteins in wheat and barley plants. This project will develop methodologies and a new field of research for optimising protein stability in crops. Its significance lies in defining new ways to control protein abundance to increase crop performance and quality and increase the value of recombinant proteins for biotech industries. Expected outcomes will enable the protein abundance in plant cells to be designed and control selective protein degradation in plants for the first time. Benefits will include building biotechnology capacity in WA, brokering new collaborations and providing an ideal training environment for students and postdocs.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL180100196
Funder
Australian Research Council
Funding Amount
$2,253,312.00
Summary
Development of multi-hazard resilient and sustainable infrastructure. This project aims to develop next generation construction of multi-hazard resilient structures for the safety and wellbeing of the public, society and economy, as well as structural health monitoring techniques for effective engineering asset management. Sustainable infrastructure development involves the use of green materials to reduce greenhouse gas emission, and new technologies to reduce construction and life-cycle mainte ....Development of multi-hazard resilient and sustainable infrastructure. This project aims to develop next generation construction of multi-hazard resilient structures for the safety and wellbeing of the public, society and economy, as well as structural health monitoring techniques for effective engineering asset management. Sustainable infrastructure development involves the use of green materials to reduce greenhouse gas emission, and new technologies to reduce construction and life-cycle maintenance cost. The project will use new green materials and techniques to prefabricate structural components which can be easily assembled and dismantled to meet the requirement for adaptation to technology advancement, urban planning and climate change. The project will advance the construction practice for sustainable infrastructure development.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL180100087
Funder
Australian Research Council
Funding Amount
$2,539,442.00
Summary
Predictive simulation of crystallisation. This project aims to create new methodologies for quantitatively predicting the result of crystallisation processes, which are central to industries from pharmaceutical and food manufacture through to minerals processing. The outcomes will include the commercialisation of new technologies for computer modelling, economic impact in several key industries, and capacity building in analytical skills. Target project applications includes accelerating the dev ....Predictive simulation of crystallisation. This project aims to create new methodologies for quantitatively predicting the result of crystallisation processes, which are central to industries from pharmaceutical and food manufacture through to minerals processing. The outcomes will include the commercialisation of new technologies for computer modelling, economic impact in several key industries, and capacity building in analytical skills. Target project applications includes accelerating the development cycle for pharmaceuticals and reducing scale formation within both oil/gas pipelines and desalination plants.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL120100049
Funder
Australian Research Council
Funding Amount
$3,229,566.00
Summary
A new paradigm for quantifying the resilience of marine calcifiers to ocean acidification and global warming. This multi-disciplinary research project will determine the future of coral reefs and marine calcifiers in response to rising carbon dioxide and ocean acidification. This will enable best-practice adaptive management at local and regional-scales for marine-dependent industries, and provide new hope for some of our greatest natural assets, coral reefs.