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Healthy Living After Stroke: An Online Intervention For Improving Stroke Survivor Health Behaviours And Quality Of Life
Funder
National Health and Medical Research Council
Funding Amount
$590,958.00
Summary
This study will test whether an online healthy lifestyles program helps survivors of stroke to live healthier lives, improve their quality of life and prevent a second stroke.
COMPARE- Constraint Induced Or Multi-Modal Aphasia Rehabilitation: An RCT Of Therapy For Stroke Related Chronic Aphasia
Funder
National Health and Medical Research Council
Funding Amount
$1,035,668.00
Summary
COMPARE is a 3 arm national randomised controlled trial comparing two types of intensive speech pathology treatment to usual care, for people with language disability 6 months to 3 years following stroke. After stratification by aphasia severity, participants are randomised to Multi-modality Aphasia Therapy, Constraint Induced Aphasia Therapy, or usual care. Cognitive, language, and speech assessments at baseline will enable sophisticated predictors of treatment responsiveness to be defined.
An Australasian, Multi-centre, Randomized, Double-blind, Placebo-controlled Trial Of The Efficacy Of Fluoxetine In Improving Functional Recovery After Acute Stroke
Funder
National Health and Medical Research Council
Funding Amount
$2,306,367.00
Summary
Stroke is one of the top three causes of disability. Treatments that improve recovery after stroke are lacking. We reviewed the world literature and found a number of very small studies which, together, suggest that the antidepressant drug, fluoxetine, may improve the recovery in stroke patients. AFFINITY is a large trial in 1600 Australians and New Zealanders with stroke which aims to find out whether taking fluoxetine for 6 months after a stroke improves recovery compared to a placebo.
Optimising Upper Limb Recovery Following Stroke: A Randomised Controlled Trial Of The Effects Of Botulinum Toxin-A Combined With Intensive Rehabilitation Compared To Botulinum Toxin-A Alone
Funder
National Health and Medical Research Council
Funding Amount
$1,070,230.00
Summary
The devastating loss of movement in the hand after stroke could potentially be addressed, but we currently lack of research investigating treatment interventions. This randomised controlled trial will compare the routine interventions of botulinum toxin to botulinum toxin plus best-practice therapy for both cost and clinical outcome. Findings from this trial will provide the necessary information to make decisions about what will improve spasticity and function in the hand and arm after stroke.
Very Early Rehabilitation In SpEech: An RCT Of Aphasia Therapy After Stroke
Funder
National Health and Medical Research Council
Funding Amount
$742,000.00
Summary
Aphasia affects one in three stroke survivors. It interferes with talking, understanding speech, reading and writing. Aphasia is devastating. Research suggests that very early aphasia therapy improves recovery of talking and understanding. However, over 70% of people with aphasia do not get very early treatment. This study promotes a “use it” or “lose it” approach to brain recovery and aims to show that very early aphasia therapy is beneficial and cost effective.
Circuit Class Therapy For Rehabilitation Clients. A Pragmatic Randomized Controlled Trial Of Therapy Intensity (CIRCIT).
Funder
National Health and Medical Research Council
Funding Amount
$526,361.00
Summary
Loss of independence is common after stroke, and may lead to reduced quality of life and admission to nursing home care. We will investigate if an increased amount of rehabilitation following stroke leads to improved mobility. Two ways of delivering more intense rehabilitation will be compared with usual care to find out which leads to improved physical mobility, and how they compare economically. This will allow health service providers to optimise services and will benefit people with stroke.
Affordable Technology To Improve Physical Activity Levels And Mobility Outcomes In Rehabilitation
Funder
National Health and Medical Research Council
Funding Amount
$1,465,653.00
Summary
Repetitive exercise is a crucial part of rehabilitation for people with impaired mobility but current exercise levels are insufficient for optimal outcomes. Affordable exercise-based video- and computer game technology could enable additional exercise for rehabilitation patients at a relatively low cost. We propose a randomised trial to establish the impact on physical activity and mobility of the addition of these technologies to usual care for people admitted to rehabilitation wards.
Neural Mechanisms Of Language Facilitation In Aphasia Due To Transcranial Direct Current Stimulation.
Funder
National Health and Medical Research Council
Funding Amount
$523,192.00
Summary
This project will assess the underlying neural mechanisms by which neurostimulation improves impaired language functions after stroke (aphasia). This will be accomplished by using a novel combination of functional magnetic resonance imaging and simultaneous transcranial direct current stimulation (tDCS) administered to different brain regions. These studies will provide crucial information necessary to optimise future clinical trials that combine tDCS with language therapy.
IMproving Physical ACtivity With Treadmill Training Following Stroke: The Stroke-IMPACT Trial
Funder
National Health and Medical Research Council
Funding Amount
$736,065.00
Summary
Stroke is a leading cause of disability amongst Australians. After stroke, activity levels are low, with few people able to exercise at an intensity which will reduce the risk of future cardiovascular events. This project examines the effectiveness of combining a high intensity treadmill training program with a self management approach to improve activity levels, mobility, cardiovascular risk profile in stroke survivors, increasing their independence and reducing the burden of care.
Can Real-time Biofeedback Of Foot Clearance Data Be Used To Assist With Gait Rehabilitation Following Stroke?
Funder
National Health and Medical Research Council
Funding Amount
$587,143.00
Summary
A new intervention for falls-risk minimization is proposed by providing additional visual sensory information to increase foot-ground clearance in order to walk more safely.A randomised controlled trial will be employed to assess the effects of biofeedback on foot-ground clearance during gait training. The outcome will be innovative biofeedback-based gait training that could significantly enhance existing stroke rehabilitation programs.