Pacific Labour and Australian Horticulture. This 18-month research project will investigate the costs and benefits of increasing labour mobility between the Pacific and Australia, including the feasibility of a seasonal labour program to employ agricultural workers from Pacific Island nations in the Swan Hill/Mildura region during periods of peak labour demand. It will forge a ground-breaking collaboration between an international development agency and local government to investigate how such a ....Pacific Labour and Australian Horticulture. This 18-month research project will investigate the costs and benefits of increasing labour mobility between the Pacific and Australia, including the feasibility of a seasonal labour program to employ agricultural workers from Pacific Island nations in the Swan Hill/Mildura region during periods of peak labour demand. It will forge a ground-breaking collaboration between an international development agency and local government to investigate how such a scheme might contribute simultaneously to economic and social development in Pacific Island nations (through remittances and skills transfers) and in regional Australia (by improving the labour supply to key horticultural industries).Read moreRead less
Fundamental theoretical investigation of the chemomechanical properties of clays. Australia faces significant environmental challenges, one of the most important being soil degradation. The aim of this project is to develop new and state-of-the art mathematical models describing the behaviour of clays in soils. This proposal addresses five fundamental problems in clay soil behaviour that have so far remained unanswered. The primary outcomes of this project will be new theoretical insights into t ....Fundamental theoretical investigation of the chemomechanical properties of clays. Australia faces significant environmental challenges, one of the most important being soil degradation. The aim of this project is to develop new and state-of-the art mathematical models describing the behaviour of clays in soils. This proposal addresses five fundamental problems in clay soil behaviour that have so far remained unanswered. The primary outcomes of this project will be new theoretical insights into the chemomechanical properties of clay soils, so providing the understanding required to intelligently engineer and manage our natural and built environments.Read moreRead less
A multi-scale approach to investigate desiccation cracking in clayey soils. The project plans to develop a model of the mechanism of drying shrinkage and associated cracking in soils. Soil desiccation cracking can adversely affect the stability and performance of many vital geo-infrastructures. For example, desiccation cracks have contributed to dam and slope failures incurring significant damages. Our understanding of the mechanism of drying shrinkage cracking and ways to control or avoid such ....A multi-scale approach to investigate desiccation cracking in clayey soils. The project plans to develop a model of the mechanism of drying shrinkage and associated cracking in soils. Soil desiccation cracking can adversely affect the stability and performance of many vital geo-infrastructures. For example, desiccation cracks have contributed to dam and slope failures incurring significant damages. Our understanding of the mechanism of drying shrinkage cracking and ways to control or avoid such cracking in soils is not yet fully developed. This project aims to advance knowledge of the nature of crack initiation and propagation in clayey soils induced by moisture evaporation, through the use of advanced experimental and modelling techniques. Outcomes are expected to lead to new continuum models for reliable prediction of soil desiccation cracking.Read moreRead less
A complex systems approach to granular rheology: interconnecting topology, stability, dynamics and function. The response of granular materials (e.g. soil, rocks) to applied stresses and strains will be characterised in detail. Information mined from experimental and simulation tests will be used to develop robust predictive models of granular behaviour, crucial for effective earthquake mitigation as well as greener mining and construction technologies.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0667984
Funder
Australian Research Council
Funding Amount
$210,000.00
Summary
Near Excitation Raman Micro Spectrometer. The unique properties of nanomaterials have recently been fully realized, and their use has resulted in new technologies, transforming industrial processes. Our research teams at Griffith, Monash and Queensland University of Technology develop optimal, nanostructured materials for technological applications. To maintain a competitive edge in this research, we require a near excitation Raman spectrometer. Used in-situ, it rapidly yields structural infor ....Near Excitation Raman Micro Spectrometer. The unique properties of nanomaterials have recently been fully realized, and their use has resulted in new technologies, transforming industrial processes. Our research teams at Griffith, Monash and Queensland University of Technology develop optimal, nanostructured materials for technological applications. To maintain a competitive edge in this research, we require a near excitation Raman spectrometer. Used in-situ, it rapidly yields structural information on the materials, enabling their formation and function to be better understood. This information will allow enhanced design and synthesis of nanomaterials, producing advanced products and processes for the energy, biotechnology, environmental and mining fields.Read moreRead less
Removal and degradation of microplastics using halloysite nanocomposite. The project aims to utilize halloysite clay combined with novel highly magnetized nanoparticles for the removal and degradation of microplastics in the contaminated water system. The project expects to fabricate cheap and environmentally-friendly materials using innovative chemical synthesis and surface modification for adsorption and decomposition of microplastics utilizing both high surface area of halloysite nanotubes a ....Removal and degradation of microplastics using halloysite nanocomposite. The project aims to utilize halloysite clay combined with novel highly magnetized nanoparticles for the removal and degradation of microplastics in the contaminated water system. The project expects to fabricate cheap and environmentally-friendly materials using innovative chemical synthesis and surface modification for adsorption and decomposition of microplastics utilizing both high surface area of halloysite nanotubes and catalytic activity of transition metals. This project will facilitate collaboration between multidisciplinary researchers and a vibrant group of industrial participants to advance next-generation composite materials for water treatment and ensure the supply of clean water for healthy living.Read moreRead less
Nanoporous bioaffinity adsorbents for separations in the pharmaceutical industry. This proposal aims to develop new high performance adsorbents for bioprocess engineering based on templated nanoporous silica materials. This research will lead to significant advances in advanced materials and adsorbent technology, downstream processing for the biotechnology industries, and understanding of highly specific affinity interactions used for difficult bioseparations. It will have important benefits for ....Nanoporous bioaffinity adsorbents for separations in the pharmaceutical industry. This proposal aims to develop new high performance adsorbents for bioprocess engineering based on templated nanoporous silica materials. This research will lead to significant advances in advanced materials and adsorbent technology, downstream processing for the biotechnology industries, and understanding of highly specific affinity interactions used for difficult bioseparations. It will have important benefits for processes involving protein purification, such as bioplasma processing, as well as flow on effects to other applications of adsorbent technology such as food processing and water treatment. The new adsorbents will lead to reductions in the costs, energy usage and waste generation of Australian industries.Read moreRead less
Modelling TRPV4 Skeletal Disorders Using Human IPSCs
Funder
National Health and Medical Research Council
Funding Amount
$1,171,187.00
Summary
Inherited skeletal disorders are a significant disease burden. Many gene mutations have been defined but we only have limited understanding about how they cause the disease. We will use patient skin cells and new in vitro re-programing technology to induce them to form cartilage cells to produce “disease in a dish” models of human skeletal disorders. These models will allow us to answer questions about how specific mutations cause disease and identify potential therapies
Improving Muscular Dystrophy By Targeting The ADAMTS5 Metalloproteinase
Funder
National Health and Medical Research Council
Funding Amount
$658,571.00
Summary
Muscular dystrophy is a devastating childhood disorder. There is no cure and no effective therapy to stop the disease progressing to early death. Our pilot data show that muscular dystrophy in a mouse model is dramatically improved when the Adamts5 gene is inactivated. ADAMTS5 is an enzyme that remodels the extracellular matrix around cells. This suggests that inhibiting ADAMTS5 may be a new way to treat muscular dystrophy. We will test this idea in mice with muscular dystrophy
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100006
Funder
Australian Research Council
Funding Amount
$500,000.00
Summary
X-ray Microscopy Facility for Imaging Geo-materials (XMFIG). The X-ray Microscopy Facility for Imaging Geo-Materials (XMFIG) will allow the investigation, with near-synchrotron capabilities, of the three dimensional internal structures and chemical compositions of geo-materials under relevant environmental conditions by engineers, geologists and materials scientists.