Melanoma incidence continues to rise & it remains a leading cause of cancer death in young adults. Prevention & early detection are foundations of disease control. Drug treatments for advanced disease have recently begun to extend survival but remain ineffective in many. Utilising the extensive resources of Melanoma Institute Australia (world's largest melanoma treatment centre), this research seeks to improve outcomes of patients with difficult to treat & aggressive melanomas.
Molecular Determinants Of Progression And Treatment Response In Melanoma
Funder
National Health and Medical Research Council
Funding Amount
$467,068.00
Summary
Melanoma, a skin malignancy of pigment cells, is a major Australian health problem and is the commonest cancer in young adults. This project utilises the resources of the world’s largest melanoma treatment service and aims to develop a scientific basis for 1) improved management of individuals at high risk for melanoma progression, and 2) improved treatment of patients with early and disseminated melanoma, in an era of rapid change in the prospects of successfully treating this dangerous cancer.
Determinants Of The Outcomes From Infectious Diseases
Funder
National Health and Medical Research Council
Funding Amount
$585,269.00
Summary
This Fellowship will allow Professor Lloyd to continue clinical and laboratory research in two areas: firstly, in relation to prevention of transmission of hepatitis C infection, and scale up of antiviral treatments, particularly amongst prisoners. Secondly, in studies investigating the biological basis of chronic fatigue states following acute infection or cancer treatment, and also in development of effective treatment for chronic fatigue states.
Advancing Novel Brain Stimulation Treatment For Severe Depression
Funder
National Health and Medical Research Council
Funding Amount
$575,662.00
Summary
The aim of the proposed research is to substantially escalate the development of a range of novel brain stimulation treatments for patients with severe treatment resistant depression (TRD). For example, to expand a substantive research program aimed at further developing methods for the application of repetitive transcranial magnetic stimulation (rTMS) in patients with depression.
Determinants Of The Outcomes From Infectious Diseases
Funder
National Health and Medical Research Council
Funding Amount
$532,630.00
Summary
Professor Lloyd will continue studies of the factors which lead to varied clinical outcomes from common infectious diseases. The outcomes include chronic or persistent illness, rather than prompt recovery. The factors being studied include aspects of the microbes causing the infection; and aspects of the individual suffering from infection, including genetic make-up, immune defences, and treatment responses. The infections studied include common "flu-like" illnesses, as well as hepatitis C.