AVERT-DOSE (Determining Optimal Early Rehabilitation After StrokE): A Multi-arm Covariate-adjusted, Response-adaptive Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$4,359,564.00
Summary
AVERT-DOSE is an international, investigator-led clinical trial, developed in Australia but recruiting >2500 patients from 6 countries around the world. In this trial we will establish the optimal model of early mobility rehabilitation for people with acute stroke. The protocols we develop will be suitable for adoption in clinical practice in developed and developing countries and help reduce the unacceptably high personal and community burden of stroke-related disability world wide.
Reduction Of Breast Lymphoedema Symptoms Secondary To Breast Cancer: A Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$600,395.00
Summary
Breast lymphoedema is a consequence of treatment for breast cancer that is not typically discussed, despite more than 1/3 of women with lymphoedema reporting symptoms in the breast. To date, no study has investigated the impact of exercise on breast lymphoedema symptoms. The aim of this study is to determine if a general exercise program is safe, acceptable and effective in reducing symptoms for women with breast lymphoedema.
Clinical Trial Of Rehabilitation After Ankle Fracture
Funder
National Health and Medical Research Council
Funding Amount
$443,348.00
Summary
Over 20,500 Australians fracture their ankle each year. Initially the fracture is managed with cast immobilisation, sometimes after surgery. Pain, stiffness, weakness and swelling are disabling consequences of fracture and cast immobilisation, and can prevent return to work and sport. This trial will determine the effects and cost of rehabilitation (a physiotherapy exercise program) implemented after cast removal, and enable provision of evidence-based treatment for this very common problem.