Predicting the value and use of urban land. This project aims to develop a comprehensive, robust and user-friendly set of modelling tools to predict land values more accurately. Accurate predictions of land values reduce state government revenue risks and improve resource management. The expected outcome of this project is the development of modelling tools which, can be used to study land use allocation, infrastructure delivery and government taxation revenue. This should provide significant be ....Predicting the value and use of urban land. This project aims to develop a comprehensive, robust and user-friendly set of modelling tools to predict land values more accurately. Accurate predictions of land values reduce state government revenue risks and improve resource management. The expected outcome of this project is the development of modelling tools which, can be used to study land use allocation, infrastructure delivery and government taxation revenue. This should provide significant benefits such as the development of new econometric theory, advanced computational methods and evidence-based guidelines for policymakers.Read moreRead less
Statistical methods for quantifying variation in spatiotemporal areal data. This project aims to develop new statistical methods for extracting insights into spatial and temporal variation in areal data. These tools will extend the Australian Cancer Atlas which provides small area estimates for 20 cancers across Australia. The project is significant because it will allow government and other organisations to reap dividends from investment in collecting spatial information and it will enable mode ....Statistical methods for quantifying variation in spatiotemporal areal data. This project aims to develop new statistical methods for extracting insights into spatial and temporal variation in areal data. These tools will extend the Australian Cancer Atlas which provides small area estimates for 20 cancers across Australia. The project is significant because it will allow government and other organisations to reap dividends from investment in collecting spatial information and it will enable modelled small-area estimates to be released without compromising confidentiality. The expected outcomes include new statistical knowledge and new insights into cancer. The results will benefit the many disciplines, managers and policy makers that make decisions based on geographic data mapped over space and time. Read moreRead less
New hyphenated chromatographic and spectroscopic methods for oil analysis. This project aims to use novel chemical separation methods combined with spectroscopy to identify useful markers in olive oil and essential oil to ensure purity, quality and authenticity, which are all ongoing issues in these industries in Australia and overseas. The project plans to compare and integrate results of multidimensional gas chromatography combined with mass spectrometry and Fourier transform infrared analyses ....New hyphenated chromatographic and spectroscopic methods for oil analysis. This project aims to use novel chemical separation methods combined with spectroscopy to identify useful markers in olive oil and essential oil to ensure purity, quality and authenticity, which are all ongoing issues in these industries in Australia and overseas. The project plans to compare and integrate results of multidimensional gas chromatography combined with mass spectrometry and Fourier transform infrared analyses with data libraries to generate precise molecular identification. The outcome is expected to help monitor adulteration of oils and maintain the high quality standards of Australian produce.Read moreRead less
Innovative approach to design a new osseointegrated implant for transfemoral amputees with better resistance to fractures. Transfemoral amputees fitted with an osseointegrated implant are experiencing numerous valuable benefits compare to their previous method conventional attachment. However, 40% of them present an early loosening of the implant or ruptures of the abutment. These problems are related to the load regime acting on the fixation system during post-operative rehabilitation and daily ....Innovative approach to design a new osseointegrated implant for transfemoral amputees with better resistance to fractures. Transfemoral amputees fitted with an osseointegrated implant are experiencing numerous valuable benefits compare to their previous method conventional attachment. However, 40% of them present an early loosening of the implant or ruptures of the abutment. These problems are related to the load regime acting on the fixation system during post-operative rehabilitation and daily life activities. In this project, the direct measurement of the actual load applied on the abutment during:
· the load bearing exercises is essential to refine the post- operative rehabilitation program.
· every-day activities is crucial to improve the design and
testing of the implants and abutments.Read moreRead less
Borderline Personality as Social Phenomena. Mental disorders attract social stigma and those diagnosed are widely misunderstood. This project aims to collect and analyse accounts of people living with Borderline Personality Disorder (BPD) - mainly women - and perspectives of social support practitioners. The intended outcome is to provide a sophisticated understanding of BPD as a social phenomenon, develop sociological evidence based on lived experiences and generate Australian digital resources ....Borderline Personality as Social Phenomena. Mental disorders attract social stigma and those diagnosed are widely misunderstood. This project aims to collect and analyse accounts of people living with Borderline Personality Disorder (BPD) - mainly women - and perspectives of social support practitioners. The intended outcome is to provide a sophisticated understanding of BPD as a social phenomenon, develop sociological evidence based on lived experiences and generate Australian digital resources including narratives of BPD, creative outputs and practitioner perspectives. The anticipated goal of this project is to inform policy and community responses addressing stigma and marginalisation, and the improvement of social support for those affected by BPD.Read moreRead less
Gaining insights into mine waste dumps to avoid environmental legacies. The project aims to develop new methods for identifying pollution source hotspots and pathways inside mine waste rock dumps. This addresses the national need for effective management of Acid and Metalliferous Drainage (AMD), which is now a critical consideration in the viability of new mines and in confronting pollution legacies of old mines. The research will develop and test innovative methods of geophysical and geochemica ....Gaining insights into mine waste dumps to avoid environmental legacies. The project aims to develop new methods for identifying pollution source hotspots and pathways inside mine waste rock dumps. This addresses the national need for effective management of Acid and Metalliferous Drainage (AMD), which is now a critical consideration in the viability of new mines and in confronting pollution legacies of old mines. The research will develop and test innovative methods of geophysical and geochemical analysis and their integration that provide 3-dimensional mapping of key physical and chemical features of the dump. Expected outcomes include greater confidence in the ability of the mining industry to manage its AMD liability. Read moreRead less
Enhancing social research in Australia using dual-frame telephone surveys. The growing surge in mobile phones and mobile-phone only households has had a significant impact on the representativeness of social surveys and accuracy of social outcome measures. This project will develop methods for generating sampling lists of both types of telephone numbers to improve population coverage and accuracy of outcome measures.
Protein biosensors for detecting smoke exposure of grapes. Bush fires and controlled burns that take place in the vicinity of vineyards can lead to grape contamination with tasteless phenolic glucosides. Their hydrolysis during wine making leads to “smoke taint” – an unpleasant medicinal taste that can render wine undrinkable. We will apply a combination of organic synthesis, protein engineering and directed evolution to develop protein-based biosensors of phenolic glucosides. These biosensors w ....Protein biosensors for detecting smoke exposure of grapes. Bush fires and controlled burns that take place in the vicinity of vineyards can lead to grape contamination with tasteless phenolic glucosides. Their hydrolysis during wine making leads to “smoke taint” – an unpleasant medicinal taste that can render wine undrinkable. We will apply a combination of organic synthesis, protein engineering and directed evolution to develop protein-based biosensors of phenolic glucosides. These biosensors will be used to devise a simple portable colorimetric test that can be performed in the vineyard or the winery. The ability to rapidly determine the level of grape contamination with phenolic glucosides would give Australian wine growers and wine makers a powerful tool to mitigate the effects of bushfires.Read moreRead less
Integrative brain imaging technologies. This project aims to develop quantitative metabolic imaging using simultaneous magnetic resonance imaging (MRI) and positron emission tomography (PET). The current generation of MR-PET scanners are capable of simultaneously acquiring MRI and PET data to enable quantitative anatomical, physiological and metabolic imaging. The project aims to develop new MRI methods for quantitative anatomical mapping, MR-based motion correction of dynamic PET scan data, and ....Integrative brain imaging technologies. This project aims to develop quantitative metabolic imaging using simultaneous magnetic resonance imaging (MRI) and positron emission tomography (PET). The current generation of MR-PET scanners are capable of simultaneously acquiring MRI and PET data to enable quantitative anatomical, physiological and metabolic imaging. The project aims to develop new MRI methods for quantitative anatomical mapping, MR-based motion correction of dynamic PET scan data, and joint estimation of physiological and metabolic organ activity. These advances will create innovative imaging technologies for advanced biomedical imaging research with a particular emphasis in healthy ageing.
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Bone tissue engineering using innovative tubular dual-layered nanofiber meshes. Lifetime risks for long-bone fractures in Caucasians over the age of 50 are 17 per cent for women and 6 per cent for men. A clear therapeutic need exists to address the ever-increasing problems of diminished productivity and reduced quality of life associated with bone disorders as the population ages. To address this challenge, the project’s multidisciplinary, international team will develop technologies to heal tib ....Bone tissue engineering using innovative tubular dual-layered nanofiber meshes. Lifetime risks for long-bone fractures in Caucasians over the age of 50 are 17 per cent for women and 6 per cent for men. A clear therapeutic need exists to address the ever-increasing problems of diminished productivity and reduced quality of life associated with bone disorders as the population ages. To address this challenge, the project’s multidisciplinary, international team will develop technologies to heal tibial defects. Furthermore, it will establish Australia's prominence in the tissue engineering field, training the next generation of young scientists and engineers. This technology will be of interest to numerous research groups and companies worldwide and will foster international collaboration, placing Australia at the forefront of this emerging field.Read moreRead less