The Inhibition Of Biotin Protein Ligase As A New Source Of Antibiotics
Funder
National Health and Medical Research Council
Funding Amount
$750,167.00
Summary
We have become so accustomed to treating bacterial infections with antibiotics that it is hard to imagine life without them. However, the emergence of drug-resistance is creating a global health care crisis. Recently, there has not been enough attention paid to replacing old antibiotics with new products to combat drug resistance. Our team is addressing this challenge. We have discovered a new class of antibiotic that is unlike any other drug in clinical use.
Developing Inhibitors Of An Essential Histidine Kinase In Staphylococcus Aureus
Funder
National Health and Medical Research Council
Funding Amount
$578,352.00
Summary
Staphylococcus aureus (Golden staph) has been termed a "superbug" because of its persistent ability to acquire resistance to a wide range of antibiotics. Once considered primarily a hospital-acquired pathogen, many patients are now being infected with antibiotic-resistant Golden staph outside of hospitals. The primary aim of this research program is to develop new antibiotics to treat antibiotic-resistant strains of Staphylococcus aureus and related pathogens.