Promoting Recovery After Neurotrauma: Basic Science, Clinical Trials And Community Engagement
Funder
National Health and Medical Research Council
Funding Amount
$356,269.00
Summary
To promote recovery after neurotrauma by controlling the spread of damage and by maximising function in surviving circuits. The work involves animal models & nanotechnology as well as clinical rehabilitation trials in humans with spinal cord injury.
3D Histological And MRI Atlases Of Brain And Spinal Cord For Research And Clinical Practice
Funder
National Health and Medical Research Council
Funding Amount
$876,005.00
Summary
This project uses imaging techniques to produce the next generation of maps of the central nervous system. It will advance our understanding of the organisation and structure of the brain and spinal cord of humans and experimental animals, paving the way for the development of psychotherapeutic drugs and more accurate interventions on the human brain. The new maps will help those who study the brain of patients with diseases such as Alzheimer’s, Parkinson’s or animal models of these diseases.
I am a neuroscientist investigating the functional roles of neurotrophic factors in nervous diseases such as Alzheimer’s disease and spinal cord injury. I am also interested in the mechanisms of how these factors are involved in neural development.
Stem Cell Niches: Biology And Therapeutic Applications
Funder
National Health and Medical Research Council
Funding Amount
$640,210.00
Summary
This research aims to identify how stem cells are regulated in the body in order to improve therapies for blood disorders and abnormal bone formation after severe traumas. Targeting molecules that deregulate stem cells will lead to improved treatments for diseases with outcomes including improved treatments for blood stem cell transplantation, improved therapy in cancer patients and reduced complications of spinal cord injuries.
My work investigates the neural output to human inspiratory muscles and how it is related to mechanical effectiveness for breathing. The aim is to discover how this relationship can change with respiratory disorders such as chronic obstructive pulmonary disease and obstructive sleep apnoea. I also examine the changes in breathing muscle control in people with spinal cord injury. This work promises new understanding of the basic control of respiration and how it changes with disease.