Bridging the meaning gap: A computational approach to semantic variation. This project aims to create and validate a new class of large language models that capture and partially explain semantic variation between people. We will (1) measure nuanced differences in word meaning and linguistic experience across individuals; (2) develop computational models that incorporate this variation; and (3) evaluate the extent to which the models capture behavioural and cognitive differences related to polit ....Bridging the meaning gap: A computational approach to semantic variation. This project aims to create and validate a new class of large language models that capture and partially explain semantic variation between people. We will (1) measure nuanced differences in word meaning and linguistic experience across individuals; (2) develop computational models that incorporate this variation; and (3) evaluate the extent to which the models capture behavioural and cognitive differences related to political affiliation, gender, and culture. This will advance our understanding of the nature and origin of individual differences as well as improve the calibration of AI systems for under-represented groups. These advances will support eventual applied outcomes in health, domestic security, and resilience to misinformation. Read moreRead less
Fairness in Natural Language Processing. Natural language processing (NLP) has achieved spectacular commercial successes in recent years, and has been deployed across an ever-increasing breadth of devices and application areas. At the same time, there has been stark evidence to indicate that naively-trained models amplify biases in training data, and perform inconsistently across text relating to different demographic groupings of individuals. This project aims to systematically quantify the ext ....Fairness in Natural Language Processing. Natural language processing (NLP) has achieved spectacular commercial successes in recent years, and has been deployed across an ever-increasing breadth of devices and application areas. At the same time, there has been stark evidence to indicate that naively-trained models amplify biases in training data, and perform inconsistently across text relating to different demographic groupings of individuals. This project aims to systematically quantify the extent of such biases, and develop models that are both more socially equitable, as well as less prone to expose private data in the learned representations. In doing so, it will make NLP more accessible to new populations of users, and remove socio-technological barriers to NLP uptake.Read moreRead less
Using visual science to reduce the dangers of night driving. This project aims to develop novel tests of visual function relevant to the modern night driving environment. Night driving is challenging for all drivers and has been linked to poor visibility under low light conditions. This project will characterise the visual challenges of the modern night driving environment, develop visual tests that incorporate the dynamic light levels typical of night-time roads and assess the association of th ....Using visual science to reduce the dangers of night driving. This project aims to develop novel tests of visual function relevant to the modern night driving environment. Night driving is challenging for all drivers and has been linked to poor visibility under low light conditions. This project will characterise the visual challenges of the modern night driving environment, develop visual tests that incorporate the dynamic light levels typical of night-time roads and assess the association of these tests with night driving performance. The outcomes will contribute new knowledge regarding dynamic visual processing and the ageing visual system and will inform vision testing, potential interventions to improve visual function for night driving and reduce the dangers of night driving.Read moreRead less
Central Representation of Electroacoustic Stimuli. Cochlear implantation, initially only provided to profoundly deaf individuals, is now routine in people with substantial residual hearing. Although stimulation via a cochlear implant and hearing aid in the same ear has been shown to improve speech understanding, particularly in noise, and to increase the aesthetic quality of sound, almost nothing is known about the physiological mechanisms underlying these benefits. The broad aim of our project ....Central Representation of Electroacoustic Stimuli. Cochlear implantation, initially only provided to profoundly deaf individuals, is now routine in people with substantial residual hearing. Although stimulation via a cochlear implant and hearing aid in the same ear has been shown to improve speech understanding, particularly in noise, and to increase the aesthetic quality of sound, almost nothing is known about the physiological mechanisms underlying these benefits. The broad aim of our project is to address this deficiency by measuring the patterns of neural activity evoked by speech sounds across the tonotopic axis in the inferior colliculus and auditory cortex and assess the extent to which the pattern of neural activity allows discrimination between the different speech sounds.Read moreRead less
Novel mechanisms for regulating the retinal vasculature. Tight control of the retinal vasculature is crucial for maintaining normal vision. Unlike most blood vessels in the body, those in the retina and brain receive no direct neural control. Rather they rely on support cells to communicate the needs of neurons. This project aims to examine the mechanisms by which resident immune cells, called microglia, regulate retinal capillaries in response to neural activity. New knowledge examining a novel ....Novel mechanisms for regulating the retinal vasculature. Tight control of the retinal vasculature is crucial for maintaining normal vision. Unlike most blood vessels in the body, those in the retina and brain receive no direct neural control. Rather they rely on support cells to communicate the needs of neurons. This project aims to examine the mechanisms by which resident immune cells, called microglia, regulate retinal capillaries in response to neural activity. New knowledge examining a novel mechanism will be generated. This information is crucial for enhancing our understanding of how blood vessels are controlled in the retina and brain and will guide the development of novel ways of examining blood vessel function.Read moreRead less
Automated assessment of data quality in biological knowledge resources. This project aims to develop methods for identifying poor quality data in biological databases. Research in biomedicine is underpinned by massive databases of biological data. Data quality is largely managed through manual curation, but automated methods to assess quality are critically needed. This project expects to develop a suite of computational tools for assessing biological data quality, utilising an innovative approa ....Automated assessment of data quality in biological knowledge resources. This project aims to develop methods for identifying poor quality data in biological databases. Research in biomedicine is underpinned by massive databases of biological data. Data quality is largely managed through manual curation, but automated methods to assess quality are critically needed. This project expects to develop a suite of computational tools for assessing biological data quality, utilising an innovative approach based on network analysis of database record connectivity. These tools will enable quantifying data quality at scale. Researchers, evidence-based decision-makers in biomedicine, and the analytical or predictive tools that use this data will make more reliable inferences and decisions.Read moreRead less
Neural plasticity in older adult human vision. This project aims to expand our understanding of age related changes in brain function, specifically plasticity. The project will increase knowledge of the role of an inhibitory neurotransmitter GABA in visual plasticity. Expected outcomes include new knowledge regarding the regulation of brain function in adulthood, enabling future research and planning for societal benefit to older Australia.
Constraint-based Reasoning for Multi-agent Pathfinding. Automation is a transformative technology for logistics -- using robots to manipulate inventory allows warehouses to be more efficient, and larger-scale, than ever before. But doing this in practice requires efficient, reliable methods for coordinating ever-larger fleets of robots. These problems are extremely difficult, and current approaches either scale poorly or give weak or no guarantees on solution quality. The project will develop t ....Constraint-based Reasoning for Multi-agent Pathfinding. Automation is a transformative technology for logistics -- using robots to manipulate inventory allows warehouses to be more efficient, and larger-scale, than ever before. But doing this in practice requires efficient, reliable methods for coordinating ever-larger fleets of robots. These problems are extremely difficult, and current approaches either scale poorly or give weak or no guarantees on solution quality. The project will develop transformative approaches to multi-agent pathfinding which can handle industrial size problems, and handle all of the complications that arise in practical applications. This will deliver improved cost-effectiveness and productivity to automated warehouse logistics and other agent coordination problems.Read moreRead less
Time Series Classification for Complex Dynamic Global Problems. This project aims to increase understanding of complex dynamic processes by creating new ways of analysing large quantities of data collected over time. These new approaches will be specifically designed to greatly improve the understanding obtained from time varying data for trillions of global earth observation data points in an application-agnostic way that is applicable to many tasks. The outcomes are expected to advance the the ....Time Series Classification for Complex Dynamic Global Problems. This project aims to increase understanding of complex dynamic processes by creating new ways of analysing large quantities of data collected over time. These new approaches will be specifically designed to greatly improve the understanding obtained from time varying data for trillions of global earth observation data points in an application-agnostic way that is applicable to many tasks. The outcomes are expected to advance the theory and practice of time-series data analysis and transform the analysis of complex dynamics. This should support innovation in industry, commerce, government and research and magnify benefit from many data investments including the $1 billion Australian governments invest annually in satellite imaging.Read moreRead less
Ultra-low fouling active surfaces. This project aims to develop chemistries and fabrication approaches through innovative materials evaluation to develop ultra-low fouling active electrode surfaces. Development of ultra-low fouling surfaces will have significant impact in a range of applications where system or device failure is attributed to fouling. The growing field of bionics, where implantable electronic devices interface directly with the nervous system, is one such device. The expected ou ....Ultra-low fouling active surfaces. This project aims to develop chemistries and fabrication approaches through innovative materials evaluation to develop ultra-low fouling active electrode surfaces. Development of ultra-low fouling surfaces will have significant impact in a range of applications where system or device failure is attributed to fouling. The growing field of bionics, where implantable electronic devices interface directly with the nervous system, is one such device. The expected outcomes will be an understanding of the material requirements that lead to the elimination of protein and cell accumulation at surfaces that degrades the performance and lifetime of these implants. The findings will benefit any application where fouling is a problem.Read moreRead less