A community based social identity approach to loneliness. Loneliness across Australia is a deep concern. Social prescribing is a novel community-based approach to managing loneliness, however it is unclear when and in what circumstances it is effective. This project aims to test a social identity approach to loneliness, incorporating longitudinal, cross-sectional, and experimental methods to understand how best to engage isolated people in group programs. The expected benefits of this project ar ....A community based social identity approach to loneliness. Loneliness across Australia is a deep concern. Social prescribing is a novel community-based approach to managing loneliness, however it is unclear when and in what circumstances it is effective. This project aims to test a social identity approach to loneliness, incorporating longitudinal, cross-sectional, and experimental methods to understand how best to engage isolated people in group programs. The expected benefits of this project are to produce a validated social prescribing model that can be implemented in multiple settings across Australia in order to reduce loneliness, strengthen communities, and guide more appropriate uses of health services.Read moreRead less
Mathematical Decision Support to Optimise Hospital Capacity and Utilisation. Hospital planners and executives regularly contend with challenging capacity related decisions. Decisions relating to prioritisation, allocation and sharing of resources have a profound impact on productivity, efficiency and patient outcomes. There is a lack of data-driven or quantitative decision support to make well-informed capacity related decisions of a strategic or tactical nature in a single hospital, or across a ....Mathematical Decision Support to Optimise Hospital Capacity and Utilisation. Hospital planners and executives regularly contend with challenging capacity related decisions. Decisions relating to prioritisation, allocation and sharing of resources have a profound impact on productivity, efficiency and patient outcomes. There is a lack of data-driven or quantitative decision support to make well-informed capacity related decisions of a strategic or tactical nature in a single hospital, or across a regional healthcare system. This project aims to deliver decision support for holistic hospital capacity assessment and planning optimisation. This will yield significant benefits for the health sector, providing a tool to optimise the allocation of resources and provision of infrastructure for regional hospital services.Read moreRead less
Confronting everyday harms: preventing abuse of people with disability. The findings of the Disability Royal Commission necessitate new approaches to prevent violence, abuse, neglect and exploitation. Framed by recognition theory, this project proposes empirical research with young people with cognitive disability, using a new concept of ‘everyday harms’ in their paid relationships. The results will inform early responses to poor quality interactions in disability support. The strategic alliance ....Confronting everyday harms: preventing abuse of people with disability. The findings of the Disability Royal Commission necessitate new approaches to prevent violence, abuse, neglect and exploitation. Framed by recognition theory, this project proposes empirical research with young people with cognitive disability, using a new concept of ‘everyday harms’ in their paid relationships. The results will inform early responses to poor quality interactions in disability support. The strategic alliances with the government, industry and community partners will develop a practice framework to prevent everyday harms and the escalation to abuse, and to promote safety and wellbeing. The research has policy benefits for capacity-building in the sector to act on the rights and voices of people with disability. Read moreRead less
Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The pr ....Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The project will provide fundamental advances in our knowledge of the nutrient transport during pregnancy that is required to produce a healthy baby.Read moreRead less
Deciphering the regulatory principles of metazoan development. This proposal aims to elucidate how regulatory elements in the genome, known as enhancers, determine the identity and function of animal tissues. Currently, it is believed that enhancers cannot be traced across evolutionarily distant animals. The project uses novel concepts, computational and molecular approaches to identify deeply conserved enhancers. It further dissects the mechanism of function by proteomics and high-throughput ge ....Deciphering the regulatory principles of metazoan development. This proposal aims to elucidate how regulatory elements in the genome, known as enhancers, determine the identity and function of animal tissues. Currently, it is believed that enhancers cannot be traced across evolutionarily distant animals. The project uses novel concepts, computational and molecular approaches to identify deeply conserved enhancers. It further dissects the mechanism of function by proteomics and high-throughput genomics. The expected outcomes will overturn our current view on enhancer evolution and reposition our understanding of how enhancers are functionally encoded in the genome. The work is an important contribution to understanding cellular complexity and species evolution with wide-ranging impact in genetics.Read moreRead less
Child health and developmental inequities: Evidence for precision policy. The project aims to use cutting edge analytic approaches applied to existing data to identify how policy interventions related to parents’ mental health, preschool programs, and the built environment can be optimised to reduce inequities in children’s mental, academic, and physical health outcomes. The project will be informed by our partners and advisers from across government portfolios and service delivery, ensuring tha ....Child health and developmental inequities: Evidence for precision policy. The project aims to use cutting edge analytic approaches applied to existing data to identify how policy interventions related to parents’ mental health, preschool programs, and the built environment can be optimised to reduce inequities in children’s mental, academic, and physical health outcomes. The project will be informed by our partners and advisers from across government portfolios and service delivery, ensuring that the evidence generated has contemporary policy relevance. The project expects to identify clear and actionable policy pathways to reduce child inequities in Australia, which can benefit decision makers by helping them to direct limited public funds towards intervention opportunities that will have the greatest impact.Read moreRead less
Visualising genetic mosaicism during development. Genetic diversity is the variation in DNA sequence among individuals. We now know that there are also differences in the DNA sequences of cells within the same individual, known as genetic mosaicism. The aims of this proposal are 1) to develop a system to visualise genetic mosaicism 2) arising during embryonic development and 3) in the brain, driven by mobile DNA activity. The expected outcome of this proposal is an unprecedented understanding of ....Visualising genetic mosaicism during development. Genetic diversity is the variation in DNA sequence among individuals. We now know that there are also differences in the DNA sequences of cells within the same individual, known as genetic mosaicism. The aims of this proposal are 1) to develop a system to visualise genetic mosaicism 2) arising during embryonic development and 3) in the brain, driven by mobile DNA activity. The expected outcome of this proposal is an unprecedented understanding of the scope and consequences of mobile DNA-driven mosaicism. This work will have significant impacts in developmental genetics and neurogenetics, and has the benefit of introducing an innovative experimental system with the potential to spark international scientific collaboration and recognition.Read moreRead less
Removal of Perfluorinated Chemicals Using New Fluorinated Polymer Sorbents. Per- and polyfluoroalkyl substances (PFAS) are a family of highly persistent chemicals that are linked to a number of human diseases, however existing approaches for removal of PFAS are highly inefficient. This project aims to develop and evaluate novel, reusable polymer sorbents for effective PFAS removal. The polymer sorbents will enable efficient, selective and continuous sorption of PFAS, while maintaining excellent ....Removal of Perfluorinated Chemicals Using New Fluorinated Polymer Sorbents. Per- and polyfluoroalkyl substances (PFAS) are a family of highly persistent chemicals that are linked to a number of human diseases, however existing approaches for removal of PFAS are highly inefficient. This project aims to develop and evaluate novel, reusable polymer sorbents for effective PFAS removal. The polymer sorbents will enable efficient, selective and continuous sorption of PFAS, while maintaining excellent environmental stability for long-term implementation in practical devices. The project will develop novel polymer sorbents to revolutionize the remediation of PFAS with high technical, economic and environmental feasibility, creating a pathway to a PFAS-free world, and ultimately protecting the natural environment.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE220100903
Funder
Australian Research Council
Funding Amount
$451,885.00
Summary
Charitable triad: How donors, beneficiaries, & fundraisers influence giving. This project aims to test a new model of charitable giving to examine how donors, beneficiaries, and fundraisers together influence donor decisions. Until now, no holistic model has existed to explain donor behaviour: past research has focused on donors but neglected beneficiaries and fundraisers. This project is expected to provide evidence for a new bedrock theory of philanthropy. Findings can also inform practitioner ....Charitable triad: How donors, beneficiaries, & fundraisers influence giving. This project aims to test a new model of charitable giving to examine how donors, beneficiaries, and fundraisers together influence donor decisions. Until now, no holistic model has existed to explain donor behaviour: past research has focused on donors but neglected beneficiaries and fundraisers. This project is expected to provide evidence for a new bedrock theory of philanthropy. Findings can also inform practitioner toolkits, offering advice to nonprofits on how to raise money effectively by understanding how the particular organisation and its beneficiaries can influence donor decisions. By helping ensure the survival of charities, this research will contribute to the delivery of essential social services that benefit many Australians.Read moreRead less