Low Strength Silver Fluoride Solutions As Clinically Effective Bacteriostatic And Cariostatic Agents
Funder
National Health and Medical Research Council
Funding Amount
$147,800.00
Summary
Scientific evidence indicates that low concentrations of silver are effective in countering bacteria involved in dental decay, and that solutions of silver fluoride are effective in stopping progression of dental decay. This study aims to determine the effectiveness of low strength silver fluoride solutions in the clinical management of dental decay in children. Such solutions may provide a simplified technique for controlling dental decay in populations which lack traditional resources
Fluoridation Of Water Supplies In Remote Indigenous Communities In The NT: Requirements, Feasibility & Cost Effectivenes
Funder
National Health and Medical Research Council
Funding Amount
$72,559.00
Summary
The project has two major objectives: 1) to identify Indigenous communities that are likely to benefit most from fluoridation of the water supply, and 2) to examine the feasibility and impact of introducing a small scale fluoridation plant into at least one community. The first will be achieved through accurately mapping natural levels of fluoride in the water supply of Indigenous communities across the Northern Territory, and examining the oral health status of children in these communities. Th ....The project has two major objectives: 1) to identify Indigenous communities that are likely to benefit most from fluoridation of the water supply, and 2) to examine the feasibility and impact of introducing a small scale fluoridation plant into at least one community. The first will be achieved through accurately mapping natural levels of fluoride in the water supply of Indigenous communities across the Northern Territory, and examining the oral health status of children in these communities. The second will be achieved by installing a fluoridation plant in one or more communities that have been lobbying for fluoridation of their water supplies, and monitoring the maintenance requirements and costs of the plant, and the changes in dental health status in school children over a period of two to three years.Read moreRead less
Physiological Function Of Nedd4-2 In Regulating The Epithelial Sodium Channel And Cystic Fibrosis Transmembrane Conductance Regulator
Funder
National Health and Medical Research Council
Funding Amount
$949,572.00
Summary
Optimal transport of sodium and chloride ions is essential for the maintenance of electrolyte balance, blood volume, blood pressure and lung function. We are studying the control of a key sodium channel (the epithelial sodium channel) and a key chloride channel (cystic fibrosis transmembrane conductance regulator) by an enzyme called Nedd4-2. This project will enable us to understand how Nedd4-2 regulates these two ion channels and to study the pathological consequences of the loss of Nedd4-2.
Randomised Control Trial Of Effectiveness Of Silver Fluoride In Managing Deciduous Dental Caries In Remote Aboriginal Communities
Funder
National Health and Medical Research Council
Funding Amount
$695,220.00
Summary
This study seeks to test a non-invasive treatment for dental decay in young children which may prevent the progression of the decay further into the tooth. This treatment is currently used in some areas. Dental decay is very common in young children in remote communities where access to dental care is often limited. The treatment may reduce pain and oral and facial infections sometimes leading to hospitalisation.