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Impact Of Disrupted Sleep And Rhythms During Pregnancy On The Mother And Her Offspring
Funder
National Health and Medical Research Council
Funding Amount
$796,979.00
Summary
Sleep disruption and circadian rhythm disturbances are emerging as a significant public health issue for all shift workers. The objective of this study is to further define and understand the effects of disrupted sleep rhythms specifically during pregnancy on the mother’s metabolism and the long term impact on the metabolic health of her offspring. The long term aim is to use the research outcomes to develop strategies for prevention of the harm to mother and child.
Does Caffeine Affect The Development Of The Very Immature Brain: Dose Response Relationship?
Funder
National Health and Medical Research Council
Funding Amount
$668,386.00
Summary
Premature birth is a major health problem worldwide. Preterm babies often develop apnoea of prematurity (AOP), which is commonly treated with caffeine. Trials indicate that preterm babies treated with low dose caffeine have less neurodevelopmental disabilities at 18 months. Higher doses of caffeine are often needed to reduce AOP but the risk of this is unknown. We will study the short and long-term effects of increasing doses of caffeine on the developing brain in a long-gestation species.