Age and Gender Related Changes in Motor Control of the Upper Airway Muscle Genioglossus During Sleep. Obstructive Sleep Apnoea (OSA) is the repetitive obstruction of the airway during sleep. Obstructions occur because muscles of the upper airway fail to keep the airway open during inspiration. The disorder is associated with cardiovascular disease and cognitive and behavioural impairment. The prevalence of the disorder increases in older adults, contributing to age-related health and behavioural ....Age and Gender Related Changes in Motor Control of the Upper Airway Muscle Genioglossus During Sleep. Obstructive Sleep Apnoea (OSA) is the repetitive obstruction of the airway during sleep. Obstructions occur because muscles of the upper airway fail to keep the airway open during inspiration. The disorder is associated with cardiovascular disease and cognitive and behavioural impairment. The prevalence of the disorder increases in older adults, contributing to age-related health and behavioural problems. However, age-related changes differ in men and women. We believe the high prevalence of OSA in older adults is due to age and gender related changes in the activity of muscles in the upper airway. We will study the behaviour of the upper airway muscle genioglossus during sleep in young, middle-aged and older men and women.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE150100406
Funder
Australian Research Council
Funding Amount
$375,936.00
Summary
Cognitive Compensation in Ageing. Decline in cognitive control can have a devastating effect on an individual's capacity to live a high quality and safe independent life. It is an untested assumption that older adults can compensate for age-related changes in cognitive control function to perform at the same level as younger adults. This project aims to be the first to test this widely-held assumption and will examine changes in cognitive control and the emergence of compensation over the adult ....Cognitive Compensation in Ageing. Decline in cognitive control can have a devastating effect on an individual's capacity to live a high quality and safe independent life. It is an untested assumption that older adults can compensate for age-related changes in cognitive control function to perform at the same level as younger adults. This project aims to be the first to test this widely-held assumption and will examine changes in cognitive control and the emergence of compensation over the adult lifespan (20 to 90 years). The project aims to establish whether cognitive compensation is an effective mechanism to maintain cognitive control function into old age and will inform future strategies to help older individuals live more successful and productive independent lives for longer.Read moreRead less
Brides and Grandmothers: Challenges for Older Filipinos in Australia. This project investigates the settlement, acculturation experiences, and psychological wellbeing of older Filipino women who arrived in Australia under different circumstances. Some have migrated to Australia as young brides to marry Australian citizens and some as grandmothers to be reunited with family members. Five hundred older Filipino women, and a group of 100 men living in rural and urban areas, will participate in the ....Brides and Grandmothers: Challenges for Older Filipinos in Australia. This project investigates the settlement, acculturation experiences, and psychological wellbeing of older Filipino women who arrived in Australia under different circumstances. Some have migrated to Australia as young brides to marry Australian citizens and some as grandmothers to be reunited with family members. Five hundred older Filipino women, and a group of 100 men living in rural and urban areas, will participate in the project. The findings will enhance the understanding of the social and psychological needs of this special group of migrants and will assist in the planning of immigration policies and culturally appropriate health services for older migrants.Read moreRead less
Examining the relationship between error processing, cognitive control and emotion: a cognitive neuroscience approach. The proposed research aims to contribute to current scientific thinking on how the processing of errors influences self-monitoring and cognitive performance. The ability to monitor one's cognitive performance deteriorates with normal ageing, and is particularly affected in a range of clinical conditions, where it is a reliable predictor of a poor prognostic outcome. This project ....Examining the relationship between error processing, cognitive control and emotion: a cognitive neuroscience approach. The proposed research aims to contribute to current scientific thinking on how the processing of errors influences self-monitoring and cognitive performance. The ability to monitor one's cognitive performance deteriorates with normal ageing, and is particularly affected in a range of clinical conditions, where it is a reliable predictor of a poor prognostic outcome. This project aims to clarify understanding of the cognitive and neural processes underlying self-monitoring, as an important first step to improving rehabilitation and management methods for age-related impairments such as Alzheimer's disease, and prominent mental health conditions such as schizophrenia.Read moreRead less
Improving cognitive function in the elderly. The ageing population has been identified as one of the major issues facing contemporary Australian society. For Australia, human ageing has significant societal, economic and, importantly, personal/human costs. The economic costs associated with ageing reflect decreased productivity as well as a higher incidence of a variety of illnesses including cardiovascular and respiratory disease and, importantly, neurological conditions such as Parkinson's dis ....Improving cognitive function in the elderly. The ageing population has been identified as one of the major issues facing contemporary Australian society. For Australia, human ageing has significant societal, economic and, importantly, personal/human costs. The economic costs associated with ageing reflect decreased productivity as well as a higher incidence of a variety of illnesses including cardiovascular and respiratory disease and, importantly, neurological conditions such as Parkinson's disease (PD) and Alzheimer's disease (AD). We will complete two large scale studies examining the efficacy of twelve months administration of two pharmacologically active supplements in reducing the cognitive effects of aging in elderly participants.
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Cardiovascular and Respiratory Activity During Sleep Onset. Going to sleep requires that behavioural and physiological activities be modified. This is achieved by the integrated activity of sleep mechanisms and the circadian system. In this project we will investigate the nature of the regulatory control exerted by sleep mechanisms over respiration and cardiovascular activity at sleep onset, how sleep control interacts with circadian influence, and the nature of cardio-respiratory activity when ....Cardiovascular and Respiratory Activity During Sleep Onset. Going to sleep requires that behavioural and physiological activities be modified. This is achieved by the integrated activity of sleep mechanisms and the circadian system. In this project we will investigate the nature of the regulatory control exerted by sleep mechanisms over respiration and cardiovascular activity at sleep onset, how sleep control interacts with circadian influence, and the nature of cardio-respiratory activity when sleep control is removed at an arousal from sleep. It is anticipated that a better understanding of the regulatory control exerted by sleep over other systems will improve our understanding of sleep disorders.Read moreRead less
Respiratory and Cardiovascular Activation at Arousal from Sleep. An arousal from sleep, no matter how brief, is assciated with increased activity in the respiratory and cardiac systems. Under normal circumstances the response is considered adaptive. However, in disorders of sleep in which individuals arouse frequently and their sleep is fragmented, such as in Obstructive Sleep Apnea, the phenomenon has been linked to hypertension. While the clinical consequences of sleep fragmentation are now ap ....Respiratory and Cardiovascular Activation at Arousal from Sleep. An arousal from sleep, no matter how brief, is assciated with increased activity in the respiratory and cardiac systems. Under normal circumstances the response is considered adaptive. However, in disorders of sleep in which individuals arouse frequently and their sleep is fragmented, such as in Obstructive Sleep Apnea, the phenomenon has been linked to hypertension. While the clinical consequences of sleep fragmentation are now apparent, the mechanism that causes the increase in physiological activity at each arousal, is not known. The aim of this project will provide insight into the mechanism that produces the activation response and provide a basis for minimising the cardiac consequences of sleep disorders.Read moreRead less
Learning from errors: examining the neural mechanisms underlying performance monitoring and adaptive behaviour. This project aims to contribute to current scientific thinking on how the brain mechanisms underlying error processing influence adaptive behaviour. Self-recognition of errors deteriorates in many clinical conditions and is a predictor of poor prognostic outcome. However, it remains unclear how such dysfunction leads to the failure to adapt behaviour.
Wellbeing in the elderly: the role of respect. Due to advances in health care, many more Australians are living to old age. It is important to ensure that older people, who comprise a significant proportion of the population, maintain high levels of quality of life (QOL). One of the factors that impact on QOL of older people is the respect afforded to them. This project will determine the issues related to respect for older people in Australia, and produce an evidence-based strategy for encoura ....Wellbeing in the elderly: the role of respect. Due to advances in health care, many more Australians are living to old age. It is important to ensure that older people, who comprise a significant proportion of the population, maintain high levels of quality of life (QOL). One of the factors that impact on QOL of older people is the respect afforded to them. This project will determine the issues related to respect for older people in Australia, and produce an evidence-based strategy for encouraging Australians to adopt more positive attitudes and behaviours related to increasing levels of respect for older people. It is expected that the project will reduce the level of ageism and enhance the status of older people in Australia.Read moreRead less
Diverse Teams and Health Care - Problem or Cure? Research that is able to improve the quality of work life and patient care of health care professionals is vital to communities around Australia where work pressures placed on healthcare professionals are at an all time high as are shortages of qualified personnel. The research team brings together leading edge researchers in healthcare management, diversity, teamwork and workplace management. The project will result in a comprehensive descripti ....Diverse Teams and Health Care - Problem or Cure? Research that is able to improve the quality of work life and patient care of health care professionals is vital to communities around Australia where work pressures placed on healthcare professionals are at an all time high as are shortages of qualified personnel. The research team brings together leading edge researchers in healthcare management, diversity, teamwork and workplace management. The project will result in a comprehensive description of the types of diverse teams working in hospitals, policy and practice and will make recommendations for diversity management in the healthcare system, and the development of new international research collaborations in hospital research and development.Read moreRead less