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Discovery Early Career Researcher Award - Grant ID: DE230100377
Funder
Australian Research Council
Funding Amount
$423,659.00
Summary
Facilitating control of Queensland fruit fly and other insect pests. This project aims to address the need for a Queensland fruit fly male-only sterile release strain for the national Sterile Insect Technique program to control this devastating Australian horticulture pest. By combining two molecular technologies in a new strain that responds to temperature cues to trigger development of only male flies, this project expects to produce twice as many sterile males for release to mate with wild fe ....Facilitating control of Queensland fruit fly and other insect pests. This project aims to address the need for a Queensland fruit fly male-only sterile release strain for the national Sterile Insect Technique program to control this devastating Australian horticulture pest. By combining two molecular technologies in a new strain that responds to temperature cues to trigger development of only male flies, this project expects to produce twice as many sterile males for release to mate with wild females in fruit fly outbreak areas, preventing production of the next generation. Expected outcomes include significant reduction in production costs and increased efficiency of the national sterile release program, facilitating control of this damaging pest to protect Australia's billion dollar horticultural industry.Read moreRead less
Countdown to death: defining new signalling events preceding cell death . This proposal aims to understand how programmed cell death molecular machineries promote innate immune responses and proliferation by identifying new molecules that regulate these fundamental biological processes. This project expects to enhance our basic understanding of cell death, cell proliferation and innate immunity using innovative approaches and to build interdisciplinary collaborations. The new generated knowledge ....Countdown to death: defining new signalling events preceding cell death . This proposal aims to understand how programmed cell death molecular machineries promote innate immune responses and proliferation by identifying new molecules that regulate these fundamental biological processes. This project expects to enhance our basic understanding of cell death, cell proliferation and innate immunity using innovative approaches and to build interdisciplinary collaborations. The new generated knowledge in these critical processes will be fertile ground to develop innovative applications in biomedical industries. This this will have a positive impact on the health and economy of Australian society.Read moreRead less