Assessment Of Remote Ischemic Conditioning On Post-cardiac Arrest Myocardial Dysfunction By Magnetic Resonance Imaging, Invasive Coronary Hemodynamic Measurements And Markers Of Inflammation
Funder
National Health and Medical Research Council
Funding Amount
$265,881.00
Summary
Cardiac arrest and heart attack continue to cause unacceptably high mortality and morbidity. Even following successful resuscitation many people do not recover due to the inflammation caused by a lack of blood flow. We will investigate remote ischemic conditioning, utilizing a combination of world class imaging with heart MRI, flow monitors directly in heart arteries and markers of inflammation, We aim to determine the impact and recovery to the heart, brain and circulation of this new therapy.
Safer Fluid Resuscitation- Which (type), What (to Expect) And How (mechanisms)
Funder
National Health and Medical Research Council
Funding Amount
$189,384.00
Summary
Intravenous fluid administration to patients is the most common clinical intervention, often done to help sick patents get better, however paradoxically it is associated with worsening oxygen levels and increased death rates. In humans and animal I have demonstrated increased respiratory dysfunction with its administration. This study aims to understand the efficacy, compare different types of fluids and establish safer fluid administration thereby decreasing patient suffering and death rates.