The Australian Research Data Commons (ARDC) invites you to participate in a short survey about your
interaction with the ARDC and use of our national research infrastructure and services. The survey will take
approximately 5 minutes and is anonymous. It’s open to anyone who uses our digital research infrastructure
services including Reasearch Link Australia.
We will use the information you provide to improve the national research infrastructure and services we
deliver and to report on user satisfaction to the Australian Government’s National Collaborative Research
Infrastructure Strategy (NCRIS) program.
Please take a few minutes to provide your input. The survey closes COB Friday 29 May 2026.
Complete the 5 min survey now by clicking on the link below.
Over the next 5 years my team and I plan to study parasite invasion and blood cell enslavement to guide the design of better vaccines and medicines. Malaria as a deadly parasitic disease caused by large-scale infection of the body’s red blood cells. To design more effective vaccines and improved drugs to globally eliminate malaria we need to improve our understanding of how parasites infect and enslave our blood cells so they can grow rapidly and avoid our immune system.
Optimising Treatment And Prevention Strategies To Accelerate Malaria Elimination
Funder
National Health and Medical Research Council
Funding Amount
$2,163,220.00
Summary
Elimination of malaria requires the assessment of interventions that not only treat individual infections successfully but also prevent disease at a population level. My proposal brings together data science approaches and mathematical modelling to develop new methods to assess antimalarial treatments and radical population interventions, and identify markers of drug resistance, accelerating malaria elimination efforts and building capacity in this emerging cross-disciplinary field.
We will investigate malaria, a parasitic disease that kills over 630,000 people a year. We will explore the function of proteins responsible for cleaving and activating a cascade of proteins important in infection of humans and transmission of the parasite to mosquitoes. We will characterize the proteins involved in these critical events, as they are potential targets for drugs.
Structural Biology Of Malaria Parasite Invasion And Antibodies-mediated Inhibition
Funder
National Health and Medical Research Council
Funding Amount
$1,562,250.00
Summary
Malaria results in significant mortality but an effective vaccine does not yet exist. The Rh5-CyRPA-Ripr complex is essential for malaria parasite to invade erythrocytes and is the leading vaccine candidate. We aim to visualise the atomic details of the Rh5-CyRPA-Ripr complex during parasite invasion of erythrocytes and how antibodies neutralise this key protein complex. This information will advance knowledge on malaria parasite invasion, which will help to design an effective malaria vaccine.
Advancing The Radical Cure Of Plasmodium Vivax Malaria Through Optimal Antimalarial Regimens
Funder
National Health and Medical Research Council
Funding Amount
$566,164.00
Summary
Forty percent of the global population are at risk of vivax malaria and its associated morbidity. Complete cure of vivax malaria can result in severe anaemia caused by adverse effects of primaquine in vulnerable individuals. My research will provide important evidence for national malaria programs and clinicians, identifying the optimal dosing regimen across different ages and locations, that balances the risks and benefits of primaquine treatment.