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Cardiovascular Responses To Stress And Arousal: Hypothalamic And Brainstem Mechanisms
Funder
National Health and Medical Research Council
Funding Amount
$566,468.00
Summary
Stressful episodes in everyday life cause increases in blood pressure, mainly via activation of nerves that constrict blood vessels and increase heart rate. This in turn increases the risk of heart attacks, strokes, or other cardiovascular diseases. This project aims to identify the brain mechanisms that cause these stress-evoked effects. This knowledge may lead to much more effective ways of minimising stress-evoked responses, and thus reduce the risk of cardiovascular disorders.
CENTRAL BLOCKADE OF SYMPATHETIC RESPONSES TO EMOTIONAL STRESSORS
Funder
National Health and Medical Research Council
Funding Amount
$313,933.00
Summary
Emotional stress triggers physiological reactions that affect our heart and blood pressure. For people with a weak or failing heart, this can lead to stroke and death. This project explores the effects and the sites of action in the brain of two different types drugs that could potentially reduce or prevent such accidents. Unlike the drugs that are currently in use, these two drugs act directly in the parts of the brain that control cardiovascular responses to emotional stress.