NHMRC Centre Of Research Excellence For Better Outcomes In Coronary Artery Disease
Funder
National Health and Medical Research Council
Funding Amount
$2,500,000.00
Summary
One Australian suffers a heart attack every 10 min, many without any prior warning. What contributes to atherosclerosis beyond traditional risk factors, and how to manage patients that suffer a heart attack despite no risk factors is not well known. This CRE will establish new biomarkers and clinical pathways for detection of subclinical atherosclerosis as well as secondary prevention strategies whilst fostering the cardiovascular research leaders of the future.
PROBE-NET: The Progression Of Barrett's Esophagus To Cancer Network
Funder
National Health and Medical Research Council
Funding Amount
$2,465,844.00
Summary
This application brings together the seven major research teams in Australia with expertise in oesophageal neoplasia to form a multi-state, multi-disciplinary Centre for Research Excellence. All of the nodes have worked together collaboratively for the past 4 years, pooling their expertise in surgery, gastroenterology, endoscopy, epidemiology, biostatistics, basic science, health policy and translational research. Our vision is to develop evidence-based strategies for reducing the burden of oeso ....This application brings together the seven major research teams in Australia with expertise in oesophageal neoplasia to form a multi-state, multi-disciplinary Centre for Research Excellence. All of the nodes have worked together collaboratively for the past 4 years, pooling their expertise in surgery, gastroenterology, endoscopy, epidemiology, biostatistics, basic science, health policy and translational research. Our vision is to develop evidence-based strategies for reducing the burden of oesophageal neoplasia.Read moreRead less
Bowel cancer, the second most diagnosed and cause of cancer death is preventable. Low risk people need no screening or just inexpensive fecal occult blood tests. Increased risk people need the more expensive and invasive colonoscopies. There is overuse of colonoscopy by those at low risk and underuse by those at high risk. Our Centre brings together scientists, epidemiologists and clinicians to develop a personalised risk tool and methods to implement the tool to increase appropriate screening.
Centre For Research Excellence In Critical Infectious Diseases
Funder
National Health and Medical Research Council
Funding Amount
$2,623,406.00
Summary
Severe infection kills millions of people every year, but clinicians and policy makers rarely get the information they need in time to make potentially life-saving decisions about infection. We will apply modern genomics and information systems to better understand infection threats in critical care environments and explore the ethical and medicolegal aspects that may either facilitate or present barriers to important research and time-critical decision making.
In Australia, over 2000 families suffer the tragedy of stillbirth each year. By building on our achievements of the first Stillbirth CRE rapidly translating new research into maternity care, we will reduce stillbirth rates by 20%, and reduce inequities in stillbirth rates by Australia by 2025. We also anticipate a reduction in adverse neonatal outcomes. When stillbirth or neonatal death does occur, our research aims to ensure that all women and families receive optimal care.
PRE-EMPT: Prediction Of Early Mental Disorder And Preventive Treatment - Centre Of Research Excellence
Funder
National Health and Medical Research Council
Funding Amount
$2,500,000.00
Summary
Mental health clinicians currently do not have the means to predict which young people with emerging symptoms are most at risk of progressing to serious mental illness. This CRE will help us better understand how mental illnesses develop, identify the risk and protective factors, and introduce tools for use in clinical practice to better predict onset of serious mental illness. This will help with providing and further developing early treatments to delay or prevent the onset of mental illness.
Australian is one of a few high income countries that does not have a healthy housing policy. As a consequence we fail to leverage the enormous potential for housing and housing focussed interventions to have a positive impact on population health in Australia. Our Centre for Research Excellence will provide Australian specific evidence, work with key stakeholders to make change and build capacity in the overlapping domains of housing and health.
Centre Of Research Excellence In Melanoma: Person, Tumour And System-focussed Knowledge To Drive Better Outcomes In Melanoma
Funder
National Health and Medical Research Council
Funding Amount
$2,486,945.00
Summary
This Centre for Research Excellence in Melanoma will address three pivotal questions: how best to identify and conduct surveillance of the person with a high risk of melanoma, how best to manage the person who has developed a melanoma with high potential for relapse, and how best to improve support, survivorship and the patient experience. Economic evaluation, policy and implementation research are integral to the research plan.
On TRACK (Teaching, Research And Community Knowledges) : CRE Promoting Brain Health With Older Aboriginal And Torres Strait Islander Peoples.
Funder
National Health and Medical Research Council
Funding Amount
$3,000,000.00
Summary
Aboriginal and Torres Strait Islander peoples experience high rates of dementia at younger ages of onset, having far reaching consequences for the person, their family and their communities. The OnTRACK (Teaching, Research and Community Knowledges) Centre for Research Excellence will generate knowledge about culturally safe approaches to optimise the well being and quality of life of Aboriginal and Torres Strait Islander peoples at risk of or living with dementia.
Centre For Research Excellence In Total Joint Replacement OPtimising OUtcomes, Equity, Cost Effectiveness And Patient Selection (OPUS)
Funder
National Health and Medical Research Council
Funding Amount
$2,500,000.00
Summary
Joint replacement surgery is one of the most successful surgeries performed in Australia and globally. With an ageing population, demand for this procedure will increase dramatically, placing burden on a constrained health system. This Centre targets the journey of patients undergoing joint replacement surgery, seeking to optimise patient safety and outcomes, in addition to improving efficiencies and equitablity of this important surgical procedure.