Discovery Early Career Researcher Award - Grant ID: DE130101577
Funder
Australian Research Council
Funding Amount
$374,057.00
Summary
Retail price promotions in Australia: are consumers really better off? The number and variety of retail price promotions can confuse consumers, leading to poor purchase decisions. This project will explore how promotions affect consumer choices, with a view to improving consumers' understanding and the use of retail promotions to their advantage.
Wicked defaults: how to overcome the dark side of choice architecture. This project aims to investigate how defaults and product complexity might be used to exploit consumers in environments like private insurance where consumers are prone to making systematic errors. Defaults are used to nudge individuals into socially beneficial actions such as increasing their retirement savings and joining organ donor lists. However, in the hands of firms, defaults can also be used to exploit consumers by en ....Wicked defaults: how to overcome the dark side of choice architecture. This project aims to investigate how defaults and product complexity might be used to exploit consumers in environments like private insurance where consumers are prone to making systematic errors. Defaults are used to nudge individuals into socially beneficial actions such as increasing their retirement savings and joining organ donor lists. However, in the hands of firms, defaults can also be used to exploit consumers by encouraging choices that help the firm but disadvantage consumers. The project intends to study experimentally whether exploitation can be reduced via competition and reputation building systems based on consumer feedback.Read moreRead less
ESTIMATION OF INDIGENOUS MORTALITY WHERE DESIGNATION OF INDIGENOUS STATUS ON DEATH CERTIFICATES IS UNRELIABLE
Funder
National Health and Medical Research Council
Funding Amount
$158,840.00
Summary
Mortality of indigenous Australians is regarded as unacceptably high compared to other Australians and compared to indigenous minorities in other similar countries. Indigenous mortality is based on data from WA, SA and NT, although some of the data are unreliable. There are few reliable data available in Qld, NSW, Vic or Tas because Indigenous status is significantly under-recorded on the death certificate. The objective of the research is to devise and validate indirect methods for estimating i ....Mortality of indigenous Australians is regarded as unacceptably high compared to other Australians and compared to indigenous minorities in other similar countries. Indigenous mortality is based on data from WA, SA and NT, although some of the data are unreliable. There are few reliable data available in Qld, NSW, Vic or Tas because Indigenous status is significantly under-recorded on the death certificate. The objective of the research is to devise and validate indirect methods for estimating indigenous mortality in sub-populations where there are significant proportions of indigenous people, and where designation of indigenous status on death certificate is unreliable. This would permit assessment of mortality differentials and trends in a significant number of Aboriginal and Torres Strait Islander communities in Qld, NSW, Vic and possibly Tas and provide new perspectives in the study of determinants of mortality in indigenous populations through comparisons of communities with relatively high and relatively low mortality, and allow population-based evaluation of the effectiveness of services and programs through surveillence of mortality trends and differentials. The methods rely on the basic premise that the total mortality of a population is contributed to by the mortality of its components in relation to their proportion of the total population. The units of analyses will be mainly municipalities. Mortality and proportion indigenous will be used in the comparison of municipalities with similar socio-economic and geographic characteristics, and mortality by municipality will be statistically modelled using various characteristics of these populations, including proportion indigenous (using ABS data). Methods will be validated by employing them on selected WA, SA and NT mortality data where designation of indigenous staus is considered reliable. Mortality estimates will then be made for indigenous communities in NSW, Qld, and other states.Read moreRead less
Predicting The Individual Risk Of Prostate Cancer In Australian Men
Funder
National Health and Medical Research Council
Funding Amount
$348,656.00
Summary
Prostate cancer is a major cause of disability and death in Australian men. A number of factors, particularly age and family history, influence the risk of prostate cancer but, in contrast to breast cancer, we don't know what is the risk of developing prostate cancer over a period of time for a man with a specific set of risk factors. In fact, while a number of statistical models have been developed that use a woman's risk factor profile to estimate her risk of breast cancer, none is currently a ....Prostate cancer is a major cause of disability and death in Australian men. A number of factors, particularly age and family history, influence the risk of prostate cancer but, in contrast to breast cancer, we don't know what is the risk of developing prostate cancer over a period of time for a man with a specific set of risk factors. In fact, while a number of statistical models have been developed that use a woman's risk factor profile to estimate her risk of breast cancer, none is currently available for prostate cancer. We will apply standard statistical methods to existing data from the Australian Risk Factors for Prostate Cancer study and from the Australian Institute of Health and Welfare to develop a prostate cancer risk prediction model. We will test how factor like age, detailed family history, diet, baldness status and possibly previous PSA tests and prostate biopsies predict the risk. After developing the model, we will test the accuracy of the predictions in three ways. First, using existing data from the Australian Prostate Cancer Family Study, we will see whether the number of cases in a group of men is close to the number predicted by the model (calibration). Second, to test whether the model discriminate well men who develop prostate cancer from those who do not, we will collect family trees in a sample from the Melbourne Collaborative Cohort Study. We will use these data also to estimate the optimal cut point: men above this level of risk will be considered at high risk. Third, we will apply the model to existing data from the Dutch Prostate Cancer Family Study (DPCFS) to test whether the optimal cut point identify high-risk men and to validate the model in a non-Australian population. Finally, we will prepare a computer package that health professionals will use as decision-making tool in different scenarios including individual cancer risk assessment, design of prevention trials and targeting prevention programs to high-risk men.Read moreRead less
Genetic Epidemiology Of Endometrial Cancer: Towards Understanding Aetiology And Improving Risk Prediction.
Funder
National Health and Medical Research Council
Funding Amount
$353,573.00
Summary
Studies investigating thousands of genetic markers have revolutionised our understanding of genes involved in cancer, and shown that a single gene can be associated with multiple cancers. We will conduct the largest ever study to find new genes for endometrial cancer, the most common gynaecological cancer. Our unique approach will examine >11million markers across the genome, some specifically in regions known to be important for other cancers. Findings will be used for risk prediction models ....Studies investigating thousands of genetic markers have revolutionised our understanding of genes involved in cancer, and shown that a single gene can be associated with multiple cancers. We will conduct the largest ever study to find new genes for endometrial cancer, the most common gynaecological cancer. Our unique approach will examine >11million markers across the genome, some specifically in regions known to be important for other cancers. Findings will be used for risk prediction models.Read moreRead less
Clinical, Environmental And Genetic Factors And The Risk Of Oesophageal Cancer
Funder
National Health and Medical Research Council
Funding Amount
$145,685.00
Summary
Oesophageal cancer is a rapidly fatal disease which is becoming more common in Australia, the United States and other industrialised nations. This study will examine the mechanisms leading to the development of oesophageal cancer and aims to measure the effects of genes and environment on the burden of cancer. Ultimately, this research will help target persons at highest risk so that screening, prevention and surveillance efforts can be directed more effectively.
Modelling Of Clinic And Ambulatory Blood Pressure On Cardiovascular Risk And Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$133,957.00
Summary
Whilst ambulatory blood pressure monitoring data has been shown to be a good predictor of cardiovascular events, there remains controversy as to its utility in clinical practice. This project will use data from existing population and clinical cohort studies to examine the role of ambulatory blood pressure in risk assessment and hypertension management in Australia and around the globe. The findings are likely to have a major impact on clinical guidelines for hypertension management.
Intelligent Total Body Scanner For Early Detection Of Melanoma
Funder
National Health and Medical Research Council
Funding Amount
$499,963.00
Summary
Melanoma is the 4th most common cancer in Australia; the main screening tool is a time-consuming total body examination with a hand-held dermoscope. This project aims to develop a total body scanner using fast-refocusing lenses to take total body dermoscopy images of all skin lesions in approximately 6 minutes, integrated with a computer aided diagnostic tool providing a risk score for each lesion incorporating medical history, genotypic and phenotypic risk markers.