Self-destructing CRISPR-constructs For Targeted Genome Editing In The Retina.
Funder
National Health and Medical Research Council
Funding Amount
$679,926.00
Summary
Despite the identification of specific mutations causing many inherited retinal dystrophies, all of these conditions are currently untreatable. We have established gene-editing techniques and have developed a novel mouse model, which will serve as a robust platform for testing different techniques of gene editing in the retina. No other group in the world is known to be using this platform for gene editing and our work will expedite the clinical translation of this technology.
Using data mining methods to remove uncertainties in sensor data streams. This project will develop key techniques for removing uncertainties in sensor data streams and thus improve the monitoring quality of sensor networks. The expected outcomes will benefit Australia by enabling improved, lower-cost monitoring of natural resources and management of stock raising.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775760
Funder
Australian Research Council
Funding Amount
$101,967.00
Summary
Satellite remote sensing and GIS data processing facilities at Charles Darwin University, Darwin. Northern Australia is vast, remote and spreads across diverse and extensive landscapes. There is no centralised remote sensing and GIS facility within 2000 kilometres of the CDU, Darwin. The upgraded infrastructure at CDU will assist in strengthening the research base in this remote part of Australia. This will allow the NT researchers to focus on the environmental applications of remote sensing and ....Satellite remote sensing and GIS data processing facilities at Charles Darwin University, Darwin. Northern Australia is vast, remote and spreads across diverse and extensive landscapes. There is no centralised remote sensing and GIS facility within 2000 kilometres of the CDU, Darwin. The upgraded infrastructure at CDU will assist in strengthening the research base in this remote part of Australia. This will allow the NT researchers to focus on the environmental applications of remote sensing and GIS technologies which will have many community benefits through better management of water resources, land degradation, wetlands, cultural knowledge and sustainable use of Australian biodiversity. The infrastructure will also assist in the training of new researchers within this developing field.
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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775621
Funder
Australian Research Council
Funding Amount
$494,000.00
Summary
Mileura Widefield Array: A New Low Frequency Telescope. A new radio-quiet site for international radio astronomy is being developed at Mileura in Western Australia. We have constructed a low frequency test array on the site, and established that the site is excellent for radio astronomy. We plan to build a telescope which will observe the early universe, when stars and galaxies where first born. This will be the first telescope capable of this type of measurement of the early universe. In addi ....Mileura Widefield Array: A New Low Frequency Telescope. A new radio-quiet site for international radio astronomy is being developed at Mileura in Western Australia. We have constructed a low frequency test array on the site, and established that the site is excellent for radio astronomy. We plan to build a telescope which will observe the early universe, when stars and galaxies where first born. This will be the first telescope capable of this type of measurement of the early universe. In addition, the telescope will measure the solar wind, and its potential interactions with the earth.
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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882938
Funder
Australian Research Council
Funding Amount
$1,430,000.00
Summary
MIRA Widefield Array: a new low frequency telescope. A new radio-quiet site for international radio astronomy is being developed at Boolardy in Western Australia. We have constructed a low frequency test array on the site, and established that the site is excellent for radio astronomy. We plan to build a telescope which will observe the early universe, when stars and galaxies where first born. This will be the first telescope capable of this type of measurement of the early universe. In additi ....MIRA Widefield Array: a new low frequency telescope. A new radio-quiet site for international radio astronomy is being developed at Boolardy in Western Australia. We have constructed a low frequency test array on the site, and established that the site is excellent for radio astronomy. We plan to build a telescope which will observe the early universe, when stars and galaxies where first born. This will be the first telescope capable of this type of measurement of the early universe. In addition, the telescope will measure the solar wind, and its potential interactions with the Earth. Read moreRead less
Machine Assisted, Multi-scale Spatial and Temporal Observation and Modeling of Marine Benthic Habitats. The Integrated Marine Observing System (IMOS) science plans include sampling campaigns reliant on Autonomous Underwater Vehicle (AUV) Facility data and designed to address the issues of marine biodiversity quantification and assurance. The proposed research will directly enhance the effectiveness of these programs by speeding labour-intensive analyses, aggregating the results, and searching f ....Machine Assisted, Multi-scale Spatial and Temporal Observation and Modeling of Marine Benthic Habitats. The Integrated Marine Observing System (IMOS) science plans include sampling campaigns reliant on Autonomous Underwater Vehicle (AUV) Facility data and designed to address the issues of marine biodiversity quantification and assurance. The proposed research will directly enhance the effectiveness of these programs by speeding labour-intensive analyses, aggregating the results, and searching for ecological patterns on a national scale that would be difficult to identify using traditional approaches tuned to process-scale studies. Australian society stands to benefit by virtue of improved large-scale models of ecosystem function and reduced cost for conducting marine ecosystem investigations.Read moreRead less
Special Research Initiatives - Grant ID: SR0354575
Funder
Australian Research Council
Funding Amount
$30,000.00
Summary
Earth and Ocean Informatics and Technology Network (EON-ITnet). Sustainable resource exploration and mining onshore, as well as marine planning, exploration, and defence depend on effective cross-disciplinary investigation, sharing of expertise and technologies for integration and computational analysis of multidimensional data spaces. EON-ITNET will cross-fertilise the use of artificial intelligence, advanced computing and smart information sharing for management, analysis, visualisation and me ....Earth and Ocean Informatics and Technology Network (EON-ITnet). Sustainable resource exploration and mining onshore, as well as marine planning, exploration, and defence depend on effective cross-disciplinary investigation, sharing of expertise and technologies for integration and computational analysis of multidimensional data spaces. EON-ITNET will cross-fertilise the use of artificial intelligence, advanced computing and smart information sharing for management, analysis, visualisation and metadata modelling between these traditionally separate research groups, with the outcome of improving research efficiency and lowering costs. EON-ITNET will form an alliance with the Caltech-based GeoFramework, which is advancing a novel object-oriented data analysis environment, binding community software for Earth visualisation and simulation to 4D data bases.Read moreRead less
Supporting personalised learning in secondary schools through the use of specific mathematics assessments that reveal thinking. This project will improve numeracy standards in secondary schools, by assisting teachers to personalise the teaching of each student. Through detailed research, the project will develop sophisticated assessments that clearly reveal students' mathematical thinking. On-line diagnosis will suggest teaching activities that can bring about desired conceptual changes. The eff ....Supporting personalised learning in secondary schools through the use of specific mathematics assessments that reveal thinking. This project will improve numeracy standards in secondary schools, by assisting teachers to personalise the teaching of each student. Through detailed research, the project will develop sophisticated assessments that clearly reveal students' mathematical thinking. On-line diagnosis will suggest teaching activities that can bring about desired conceptual changes. The effectiveness of the resources will be thoroughly tested, for impact on student achievement and the mathematics teaching skills of teachers, especially those working out-of-field. Rural schools will have equal access to these resources. Good numeracy provides the foundation for life-long learning, employment satisfaction and the economic competitiveness of Australia.Read moreRead less
A more intelligent knowledge-based system apprentice. Our previous techniques already had an impact on Australian industry, with five Australian companies marketing such technology, and for three of these it is a central technology. We expect an early uptake of the enhancements we propose by these companies, greatly increasing their international competitiveness against other rule technologies. Three of these companies are very recent, so we would expect other company uptake of the new enhance ....A more intelligent knowledge-based system apprentice. Our previous techniques already had an impact on Australian industry, with five Australian companies marketing such technology, and for three of these it is a central technology. We expect an early uptake of the enhancements we propose by these companies, greatly increasing their international competitiveness against other rule technologies. Three of these companies are very recent, so we would expect other company uptake of the new enhanced technology. In turn Australian companies using the technology will improve their competitiveness in an increasingly knowledge-based economy by being able to more rapidly and easily deploy knowledge-based systems. Our previous techniques have already had a significant impact in medical practice.Read moreRead less
Special Research Initiatives - Grant ID: SR0567397
Funder
Australian Research Council
Funding Amount
$81,900.00
Summary
Earth Systems Science OPeNDAP compute server framework. This E-Research initiative will produce a compute sever to exploit data locality for access to Digital Libraries. This will allow geographically disbursed researches in all disciplines related to climate change, variability and the associated impacts, to readily analyse existing data repositories, and generate derived data products of interest, without generating a prohibitive amount of network traffic. This will facilitate collaborative ....Earth Systems Science OPeNDAP compute server framework. This E-Research initiative will produce a compute sever to exploit data locality for access to Digital Libraries. This will allow geographically disbursed researches in all disciplines related to climate change, variability and the associated impacts, to readily analyse existing data repositories, and generate derived data products of interest, without generating a prohibitive amount of network traffic. This will facilitate collaborative efforts and data sharing between Australians and international research teams.Read moreRead less