Developing Personalised Treatment For Retinal Degeneration
Funder
National Health and Medical Research Council
Funding Amount
$262,220.00
Summary
Dr Chen seeks a clinical CDF1 to support his ambition in combining his expertise in clinical management of retinal diseases with a growing track record of clinical trials and laboratory science to develop treatment for retinal degeneration. This is achieved through a patient-centred translational platform that he has established. In the next 5 years, He will identify the most suitable method for measuring progression and develop personalised therapy for a phase I clinical trial.
The Ethics And Politics Of Pharmaceutical Innovation And Translation
Funder
National Health and Medical Research Council
Funding Amount
$476,728.00
Summary
I lead a research program on the ethics and politics of pharmaceutical innovation and translation: how medicines are developed, regulated, funded and taken up into practice. I aim to help policymakers to deal with conflicts among stakeholders. Over the next 4 years I will conduct a suite of research projects on topics of immediate significance to Australian policymakers; develop a new framework for pharmaceutical ethics and create a “Pharmaceutical Ethics and Politics Network.”
The Role Of The Zinc Finger Transcriptional Repressor Znf238 During Nerve Cell Maturation
Funder
National Health and Medical Research Council
Funding Amount
$394,264.00
Summary
Proper foetal brain assembly is critical for brain function, but the underlying genetic mechanisms remain poorly defined. In this study, I will investigate a family of proteins that “turn on” neural gene expression in combination with another protein that “turns off” their expression during nerve cell development. Understanding this novel on/off mechanism for controlling gene expression in newborn nerve cells will further our understanding of how the brain is assembled.