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Breathe Well: A Centre For Research Excellence In Chronic Respiratory Diseases And Lung Ageing
Funder
National Health and Medical Research Council
Funding Amount
$2,527,082.00
Summary
Our CRE is based on common respiratory conditions covering wide spectrum of ages and severity. We will investigate how to maintain optimal respiratory health, through innovative approaches to early detection, improved therapy and adherence. We have a strong multi-disciplinary team of collaborators and we will build capacity through post-doctoral fellowships to improve our structural balance and optimise translational outputs. Tasmania is an ideal community to host a strong CCRE.
The COVID-19 pandemic has highlighted the risk of closed, indoor settings due to accumulation of aerosols generated from breathing, speaking, coughing or sneezing. Any airborne threat, whether an infectious virus or a chemical agent, will create a higher exposure in indoor settings. To mitigate this risk, using inter-disciplinary expertise, this research will improve preparedness, reduce health impacts of airborne threats, inform worker and occupant safety, building design and healthy futures.
Australian is one of a few high income countries that does not have a healthy housing policy. As a consequence we fail to leverage the enormous potential for housing and housing focussed interventions to have a positive impact on population health in Australia. Our Centre for Research Excellence will provide Australian specific evidence, work with key stakeholders to make change and build capacity in the overlapping domains of housing and health.
Asia-Pacific Pneumococcal Disease Control In The Pneumococcal Conjugate Vaccine Era
Funder
National Health and Medical Research Council
Funding Amount
$2,500,000.00
Summary
Pneumonia is one of the commonest causes of childhood death worldwide. PCV is a vaccine that prevents pneumonia but it is costly; and causes an increase in disease from strains which are not in the vaccine. Our CRE will address 2 outstanding issues: when to switch from a 3 to 2 dose PCV schedule to make it more affordable; and create new understanding of the non-vaccine strains’ impact on disease in low- and middle-income countries in the Asia-Pacific region.
Centre For Research Excellence In Advanced Cardio-respiratory Therapies Improving OrgaN Support (ACTIONS)
Funder
National Health and Medical Research Council
Funding Amount
$2,593,631.00
Summary
Artificial hearts and lungs are increasingly used to support our most critically ill patients. A greater understanding of patient-machine interaction is needed to maximise their life-preserving potential. ACTIONS CRE will research device-related complications, improve device components, develop clinical practice guidelines, train clinical and engineering researchers and explore the cost benefits of this technology ensuring all Australians can access state-of-the-art mechanical life support.
Respiratory illness in Aboriginal and Torres Strait Islander children is very common with long term consequences in Indigenous Australians. Thus prevention and/or early treatment potentially change the child’s life trajectory for lung health. Partnering key researchers in Brisbane, Sydney, New Zealand and USA, we will undertake appropriate clinical studies (treatment and preventative) that are most likely to improve lung health outcomes in young Indigenous children. We will focus on increasing p ....Respiratory illness in Aboriginal and Torres Strait Islander children is very common with long term consequences in Indigenous Australians. Thus prevention and/or early treatment potentially change the child’s life trajectory for lung health. Partnering key researchers in Brisbane, Sydney, New Zealand and USA, we will undertake appropriate clinical studies (treatment and preventative) that are most likely to improve lung health outcomes in young Indigenous children. We will focus on increasing participation of Indigenous people and end-users.Read moreRead less
Improving The Immediate And Longer-Term Health Outcomes Of Preterm Infants
Funder
National Health and Medical Research Council
Funding Amount
$2,661,088.00
Summary
Premature babies develop health problems that persist throughout life and impact on mental, physical and social well-being. As all body systems are immature at birth, premature babies can develop one or many different health problems. Many factors before, during and after birth may influence the baby’s response to different treatments. Our collaborative research program seeks to understand the big picture, to help us design better treatments that improve long term outcomes after preterm birth.
Diseases caused by the pneumococcus represent the largest cause of vaccine preventable death in the world today, mainly pneumonia and meningitis. In 2011, 16 developing countries will introduce pneumococcal conjugate vaccines, none in east Asia. Lack of research has been a major barrier to their use in the region. We have established an international centre of excellence in the field and we seek support to extend the capacity of this group and to transfer the technology to Vietnam.
The Centre For Research Excellence In Minimising Antibiotic Resistance For Acute Respiratory Infections [CREMARA]
Funder
National Health and Medical Research Council
Funding Amount
$2,455,000.00
Summary
Antibiotic resistance is threat to international health. Most antibiotics are prescribed for acute respiratory infections. The Centre for Research Excellence in Minimising Antibiotic Resistance for Acute Respiratory Infections focuses on the major contributors to resistance: antibiotic overuse and person-to-person transfer of antibiotic resistance genes. Research will inform the design, evaluation and translation of urgently needed interventions, aimed at clinicians, patients and policy-makers.