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Discovery Early Career Researcher Award - Grant ID: DE170100226
Funder
Australian Research Council
Funding Amount
$372,000.00
Summary
How innate lymphoid cells regulate mammalian lung development. This project aims to determine the ability of a subset of lung resident immune cells to promote normal lung development through the regulation of stem cells. The lung is constantly exposed to countless environmental challenges including microbes. Mammals’ local immune systems protect the lung from these challenges. This is particularly important in early-life when the lung is still developing. However, impaired lung development affec ....How innate lymphoid cells regulate mammalian lung development. This project aims to determine the ability of a subset of lung resident immune cells to promote normal lung development through the regulation of stem cells. The lung is constantly exposed to countless environmental challenges including microbes. Mammals’ local immune systems protect the lung from these challenges. This is particularly important in early-life when the lung is still developing. However, impaired lung development affects humans and livestock, costing >$3 billion p.a. The intended outcome is to identify basic biological processes involved in normal mammalian lung development, which may lead to strategies to prevent chronic lung diseases in humans and animals.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180101133
Funder
Australian Research Council
Funding Amount
$358,551.00
Summary
Linking structure and function: a new approach for understanding the lung. This project aims to develop a powerful analysis tool to measure gas transport and mixing within lungs. This project will study the mechanical workings of the lungs, using an innovative approach for analysis of lung images. The expected outcome of this project is a novel platform for investigation and understanding of lung function. It is anticipated that application of the project outcomes to medical challenges in the lo ....Linking structure and function: a new approach for understanding the lung. This project aims to develop a powerful analysis tool to measure gas transport and mixing within lungs. This project will study the mechanical workings of the lungs, using an innovative approach for analysis of lung images. The expected outcome of this project is a novel platform for investigation and understanding of lung function. It is anticipated that application of the project outcomes to medical challenges in the long-term will lead to improved diagnostics and treatments for lung diseases.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170100018
Funder
Australian Research Council
Funding Amount
$362,441.00
Summary
Engineering suspended particle sprays through controlled cavitation. This project aims to use cavitation to engineer particle size in sprays of micronised particles suspended in a propellant, and develop a physical mechanism for this process. Understanding how cavitation affects the size of agglomerates in the liquid phase and droplet size in a spray is critical to developing spray devices that require precise control over the final particle size. This will be achieved through high-resolution op ....Engineering suspended particle sprays through controlled cavitation. This project aims to use cavitation to engineer particle size in sprays of micronised particles suspended in a propellant, and develop a physical mechanism for this process. Understanding how cavitation affects the size of agglomerates in the liquid phase and droplet size in a spray is critical to developing spray devices that require precise control over the final particle size. This will be achieved through high-resolution optical imaging techniques and synchrotron X-ray diagnostics. This project is expected to provide physical insight with applications for inhaled and topical pharmaceutical sprays, and industry spray drying of food products.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE120102571
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Visualising living airways: a new x-ray technique to assess Cystic Fibrosis treatments. The ability to non-invasively observe the body's inner functions at high magnification is critical in developing new medical treatments. This project will establish an x-ray technique capable of imaging subtle biological function at high magnification and apply this technique to assessing new treatments for airways affected by Cystic Fibrosis.