The Renin Angiotensin System A Novel Target In The Treatment Of Colorectal Liver Metastases.
Funder
National Health and Medical Research Council
Funding Amount
$152,556.00
Summary
Over 4500 Australians die from colorectal cancer annually primarily from spread (metastasis) to the liver. Blockade of the renin angiotensin system (RAS) can reduce liver metastases. However, the mechanisms by which RAS blockade inhibits tumour development are poorly understood. This research will establish how RAS regulates tumour growth and how manipulation of the RAS suppresses tumours. The prospective use of RAS blockade offers an exciting opportunity in the treatment of this disease.