Towards Prevention Of Acute Kidney Injury After Cardiac Surgery
Funder
National Health and Medical Research Council
Funding Amount
$771,918.00
Summary
Open heart surgery saves thousands of lives each year in Australia, but often injures the kidney. Kidney oxygen deficiency is a major cause of kidney injury. We propose a new way to manage kidney oxygen levels during heart surgery, by measuring the level of oxygen in the urine in the bladder. We will determine whether low levels of oxygen in the urine during surgery predict later development of acute kidney injury, and whether patient management can be changed to optimize kidney oxygen levels.
Can Exercise Delay Transition To Active Therapy In Men With Low Grade Prostate Cancer? A Multi-Centre Randomized Controlled Trial.
Funder
National Health and Medical Research Council
Funding Amount
$604,429.00
Summary
Prostate cancer overdiagnosis is associated with increased rates of overtreatment and associated morbidity. Although nearly half of Australian men diagnosed with low risk prostate cancer are managed with active surveillance there are no established recommendations for slowing disease progression and delaying transition to active treatment. The proposed study would be the first to determine the efficacy of a comprehensive exercise program during active surveillance for prostate cancer.
AusDiab 3: Emerging Risk Factors For And Long-term Incidence Of Cardio-metabolic Diseases
Funder
National Health and Medical Research Council
Funding Amount
$2,616,397.00
Summary
This study will track 11,000 Australian adults over 12 years to determine how many develop diabetes, obesity, kidney and heart disease. The study will develop ways to best predict those who are going to develop these conditions before they have arisen, and will explore a range of novel risk factors to better understand these conditions.