Sustainable Farms: Tree Regeneration and the Future of Farmland Biodiversity. While many government and community initiatives aim to enhance the sustainability of Australian farming systems, none specifically target the important regional-scale threatening process of tree recruitment failure. Unless this problem is addressed urgently, many farming landscapes may be virtually treeless in the future, with severe negative ramifications for both biodiversity and agricultural productivity. 'Sustainab ....Sustainable Farms: Tree Regeneration and the Future of Farmland Biodiversity. While many government and community initiatives aim to enhance the sustainability of Australian farming systems, none specifically target the important regional-scale threatening process of tree recruitment failure. Unless this problem is addressed urgently, many farming landscapes may be virtually treeless in the future, with severe negative ramifications for both biodiversity and agricultural productivity. 'Sustainable Farms' will have major national and community benefits because it will: (1) identify more sustainable farming practices that are conducive to successful tree recruitment in the future, and (2) raise awareness about a much neglected threat to the sustainability of Australian farming landscapes.Read moreRead less
The effects of prescribed fire on biota in a diverse range of carefully managed vegetation communities. This project will be a large-scale retrospective and prospective longitudinal study of the effects of fire on the vertebrate biota (mammals, birds and reptiles) inhabiting a range of vegetation types. The key aim of this study will be to quantify changes in vertebrate biota (reptiles, birds, arboreal marsupials and terrestrial mammals) within vegetation types subject to alternate burning strat ....The effects of prescribed fire on biota in a diverse range of carefully managed vegetation communities. This project will be a large-scale retrospective and prospective longitudinal study of the effects of fire on the vertebrate biota (mammals, birds and reptiles) inhabiting a range of vegetation types. The key aim of this study will be to quantify changes in vertebrate biota (reptiles, birds, arboreal marsupials and terrestrial mammals) within vegetation types subject to alternate burning strategies. The investigation will provide critical new knowledge for use in fire management, vegetation management and biodiversity conservation within national parks, state forests and similar types of land.Read moreRead less
Building capacity for adaptive management in protected areas through improved systems for monitoring and evaluation. The project demonstrates how evaluation can lead to improved management of protected areas. Effectively managed protected areas are essential for biodiversity conservation. Improved management, and hence improved conservation outcomes will flow from enhanced use of monitoring and evaluation data in decision-making. Identifying strengths and weaknesses in management will allow mana ....Building capacity for adaptive management in protected areas through improved systems for monitoring and evaluation. The project demonstrates how evaluation can lead to improved management of protected areas. Effectively managed protected areas are essential for biodiversity conservation. Improved management, and hence improved conservation outcomes will flow from enhanced use of monitoring and evaluation data in decision-making. Identifying strengths and weaknesses in management will allow managers to better allocate resource for more effective conservation outcomes. The project establishes connections with all protected area management agencies in Australia, and will contribute to the development of national policy and practice in protected area evaluation and reporting, thus helping to meet national and international reporting obligations. Read moreRead less
Regulation Of Receptors That Control Platelet Function Under Shear Stress
Funder
National Health and Medical Research Council
Funding Amount
$507,273.00
Summary
Specialized human blood cells that control blood loss and clotting (platelets) are currently difficult to test in the clinical laboratory, meaning patients are at risk of excessive bleeding or serious clot formation during disease or treatment. The aim of this proposal is to use our new reagents and assays to develop more reliable methods for evaluating relative bleeding or clotting risk in individuals.
Autoimmune-based thrombocytopenia can be a life-threatening adverse event associated with viral load, surgery, drug therapies or the use of the anticoagulant, heparin. This grant will define mechanisms of anti-platelet antibody-dependent platelet activation and assess shedding of platelet-specific glycoprotein (GP)VI as an immediate consequence of this activation, provide a new strategy for evaluating risk of thrombosis in HIT.
An unprecedented opportunity to quantify biodiversity recovery after major wildfire. Recent fire disasters in southern Australia emphasise that wildfire is one of the major social, economic and ecological issues facing the nation. Biodiversity loss and environmental degradation are also substantial national issues. The outcomes and new understanding obtained from this project will have enormous rural, regional, national and international benefits through developing better informed, and ecologica ....An unprecedented opportunity to quantify biodiversity recovery after major wildfire. Recent fire disasters in southern Australia emphasise that wildfire is one of the major social, economic and ecological issues facing the nation. Biodiversity loss and environmental degradation are also substantial national issues. The outcomes and new understanding obtained from this project will have enormous rural, regional, national and international benefits through developing better informed, and ecologically sustainable, principles and practices for biodiversity conservation, vegetation management, and fire management. It also will guide natural resource managers such as national park staff and state forest managers in best practice methods to manage post-fire ecological recovery on land under their jurisdiction. Read moreRead less
Biodiversity conservation, vegetation restoration and landscape design. There has been considerable recent activity through major Government-funded programs to restore native vegetation. Despite extensive expenditure, the biodiversity conservation values of restoration remain very poorly known. This innovative project will address this major knowledge gap. It will generate quality data and new principles to guide restoration that maximizes biodiversity conservation. The principal aim is to estim ....Biodiversity conservation, vegetation restoration and landscape design. There has been considerable recent activity through major Government-funded programs to restore native vegetation. Despite extensive expenditure, the biodiversity conservation values of restoration remain very poorly known. This innovative project will address this major knowledge gap. It will generate quality data and new principles to guide restoration that maximizes biodiversity conservation. The principal aim is to estimate tree planting effects on vertebrates and assess whether the effects are consistent across different landscapes, farm units and regions. New insights from the project will aid the design of cost-effective and ecologically-effective restoration programs for future landscapes in rural Australian production environments.Read moreRead less
Towards sustainable floodplain communities: Assessing River Red Gum health. Floodplain vegetation in Australia has suffered severe degradation from river regulation but there is limited understanding of the functioning, responses and requirements of the ecosystem's most critical species, the River Red Gum. We will address three knowledge gaps needed for effective management of floodplain river red gums by assessing current and past health, determining stressors affecting health and by building ....Towards sustainable floodplain communities: Assessing River Red Gum health. Floodplain vegetation in Australia has suffered severe degradation from river regulation but there is limited understanding of the functioning, responses and requirements of the ecosystem's most critical species, the River Red Gum. We will address three knowledge gaps needed for effective management of floodplain river red gums by assessing current and past health, determining stressors affecting health and by building a model for predicting future health based on projected trends. Outcomes from this study will help land managers to prioritise environmental flow allocations based on the requirements for sustaining future river red gum populations.Read moreRead less
Enhancing biodiversity conservation in Australia: new insights and general principles from powerful new ecological syntheses. The innovative ecological syntheses in the exciting project aim to build Australia's national research capacity to greatly increase the effectiveness of biodiversity conservation strategies. The new insights, knowledge and practical solutions gained from this important research initiative will be critical for future visions and management of Australian landscapes. Without ....Enhancing biodiversity conservation in Australia: new insights and general principles from powerful new ecological syntheses. The innovative ecological syntheses in the exciting project aim to build Australia's national research capacity to greatly increase the effectiveness of biodiversity conservation strategies. The new insights, knowledge and practical solutions gained from this important research initiative will be critical for future visions and management of Australian landscapes. Without them we risk depleting the nation's biodiversity - which is a key issue given Australia's megadiversity status. Hence, this project addresses National Research Priority #1 - An Ecologically Sustainable Australia given its fundamental importance for key goals such as managing the nation's biodiversity and understanding natural systems. Read moreRead less
Innovative enhancement and management of threatened temperate woodlands for improved biodiversity conservation. We will test the broad question: Does woodland management affect woodland biota, and if so, which groups and in what ways? To answer this, we will quantify the effects of major woodland treatments (prescribed fire, timber addition, grazing control) on animals. We will implement a long-term, large-scale 'natural experiment' to provide critical data & analyses on the simultaneous effects ....Innovative enhancement and management of threatened temperate woodlands for improved biodiversity conservation. We will test the broad question: Does woodland management affect woodland biota, and if so, which groups and in what ways? To answer this, we will quantify the effects of major woodland treatments (prescribed fire, timber addition, grazing control) on animals. We will implement a long-term, large-scale 'natural experiment' to provide critical data & analyses on the simultaneous effects of management regimes on woodland biota. A key outcome will be an improved understanding of woodland biota response to management critical for use on grazing properties, reserves, travelling stock routes in rural south-eastern Australia. This will be a major step forward given that temperate woodlands are among Australia's most threatened vegetation types.Read moreRead less