Learning from errors: examining the neural mechanisms underlying performance monitoring and adaptive behaviour. This project aims to contribute to current scientific thinking on how the brain mechanisms underlying error processing influence adaptive behaviour. Self-recognition of errors deteriorates in many clinical conditions and is a predictor of poor prognostic outcome. However, it remains unclear how such dysfunction leads to the failure to adapt behaviour.
Examining the relationship between error processing, cognitive control and emotion: a cognitive neuroscience approach. The proposed research aims to contribute to current scientific thinking on how the processing of errors influences self-monitoring and cognitive performance. The ability to monitor one's cognitive performance deteriorates with normal ageing, and is particularly affected in a range of clinical conditions, where it is a reliable predictor of a poor prognostic outcome. This project ....Examining the relationship between error processing, cognitive control and emotion: a cognitive neuroscience approach. The proposed research aims to contribute to current scientific thinking on how the processing of errors influences self-monitoring and cognitive performance. The ability to monitor one's cognitive performance deteriorates with normal ageing, and is particularly affected in a range of clinical conditions, where it is a reliable predictor of a poor prognostic outcome. This project aims to clarify understanding of the cognitive and neural processes underlying self-monitoring, as an important first step to improving rehabilitation and management methods for age-related impairments such as Alzheimer's disease, and prominent mental health conditions such as schizophrenia.Read moreRead less
Boosting brain plasticity and motor function in older adults. Ageing is associated with a pronounced decline in many motor, cognitive, and other brain functions, but the cause remains elusive. This project will examine the mechanisms that contribute to a decline in brain plasticity and motor function in the elderly. Using novel brain stimulation techniques, the project aims to develop an optimal approach to boost plasticity in the ageing brain and improve motor function. A better understanding o ....Boosting brain plasticity and motor function in older adults. Ageing is associated with a pronounced decline in many motor, cognitive, and other brain functions, but the cause remains elusive. This project will examine the mechanisms that contribute to a decline in brain plasticity and motor function in the elderly. Using novel brain stimulation techniques, the project aims to develop an optimal approach to boost plasticity in the ageing brain and improve motor function. A better understanding of changes in brain function and plasticity with advancing age is expected to help to optimise the design of preventative programs aimed at rejuvenating motor and cognitive function in the elderly.Read moreRead less
The efficacy of a physical activity intervention in the management of psychological and physical symptoms among breast and prostate cancer patients. The vastly improved survival rates for breast and prostate cancer in recent years has resulted in an ever-increasing number of people living with a history of cancer. Treatment for cancer is often associated with negative side effects like fatigue, depression and sleep disturbance, and an overall impaired quality of life.
This project will assess ....The efficacy of a physical activity intervention in the management of psychological and physical symptoms among breast and prostate cancer patients. The vastly improved survival rates for breast and prostate cancer in recent years has resulted in an ever-increasing number of people living with a history of cancer. Treatment for cancer is often associated with negative side effects like fatigue, depression and sleep disturbance, and an overall impaired quality of life.
This project will assess the effectiveness of a physical activity program in alleviating these symptoms of treatment. The program will include regular walking and gentle resistance strength training.
The outcomes from the project will advance research by shedding light on which symptoms are most helped by physical activity, and how much activity is needed to gain these benefits.
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The neurocognitive basis of dual-task co-ordination impairment in Alzheimer’s: defective coordination mechanism or differences in speed of processing? This project explores the effects of age, depression and Alzheimer’s disease on the ability to carry out two tasks at once, to determine whether difficulty doing so is due to slowed mental processing, or to a deficit in a mechanism responsible for task coordination. The project will advance cognitive theory and may help with diagnosis of dementia.
Glucose facilitation of cognitive function: Effects of effort, age and glucose control. Age-related decline in mental capacity contributes to the economic (estimated at over 2 trillion AUD by 2050), social and human costs of an increasingly older Australian population. The studies in this program aim to understand the role of poor control of blood glucose in age-related cognitive deficits. The role of individual differences in biological (hormonal responses) and psychological (stress and appetit ....Glucose facilitation of cognitive function: Effects of effort, age and glucose control. Age-related decline in mental capacity contributes to the economic (estimated at over 2 trillion AUD by 2050), social and human costs of an increasingly older Australian population. The studies in this program aim to understand the role of poor control of blood glucose in age-related cognitive deficits. The role of individual differences in biological (hormonal responses) and psychological (stress and appetite) factors will also be assessed. A better understanding of the nature of age-related cognitive decline as it relates to biological processes such as blood glucose control will help to develop tangible strategies to combat age-related cognitive decline and dementia (which has been described as Type 3 diabetes).Read moreRead less
Make up your mind! - Dissociating the roles of orbitofrontal cortex and striatum in human decision making. How we make everyday decisions is a crucial behaviour of humans but the underlying processes in the brain are still poorly understood. This project will investigate what the roles of specific brain regions are in human decision making, which enable us to gain a better understanding of how these brain structures contribute to our decisions.
Testing theoretical models of age and disease related changes to inform prevention. Pathological brain changes associated with future cognitive decline become detectable in the 40s or earlier. Yet little is known about what constitutes normal brain ageing in mid-life. Using a number of neuroimaging and epidemiological techniques this project will scrutinise brain and cognitive ageing in middle-age and their significance.
Resolving multi-sensory conflict as we age: audio-visual integration and the role of normal and abnormal sensory decline. Australia has an ageing population. Even the healthiest older individuals undergo some deterioration of vision and hearing, however, these senses are almost invariably studied in isolation. The real world is multisensory. This project will enhance our knowledge of how ageing impacts on the interpretation of visual and auditory information regarding the timing and location of ....Resolving multi-sensory conflict as we age: audio-visual integration and the role of normal and abnormal sensory decline. Australia has an ageing population. Even the healthiest older individuals undergo some deterioration of vision and hearing, however, these senses are almost invariably studied in isolation. The real world is multisensory. This project will enhance our knowledge of how ageing impacts on the interpretation of visual and auditory information regarding the timing and location of objects; essential precursors to many real world tasks, for example: driving, interpreting speech, and hazard avoidance. This knowledge is essential for the optimisation of audio-visual environments for the elderly, and for the development of tools to improve performance in the presence of sensory decline due to age-related eye disease.Read moreRead less
Understanding the consequences of normal ageing on visual form perception. Australia has an ageing population. Within the elderly, vision is a key sense that contributes significantly to the maintenance of independence, mobility and participation in society. This project will enhance our knowledge of the impact of ageing on vision. The research findings are important to a variety of disciplines involved in planning for our ageing population; for example: the design of living/working spaces for t ....Understanding the consequences of normal ageing on visual form perception. Australia has an ageing population. Within the elderly, vision is a key sense that contributes significantly to the maintenance of independence, mobility and participation in society. This project will enhance our knowledge of the impact of ageing on vision. The research findings are important to a variety of disciplines involved in planning for our ageing population; for example: the design of living/working spaces for the elderly, information technology, and the design of technology to assist with independent living. This project will train students in visual psychophysics, continuing the strong international reputation and output of Australian scientists in this discipline.Read moreRead less